Frage 1
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Mortality rates in the first 3 months following a PE dx are:
Frage 2
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Emboli begin as thrombi which may consist of:
Antworten
-
fat
-
air
-
tumor
-
Only A & B
-
All of the above
Frage 3
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Venous thromboembolism may originate from:
Antworten
-
DVTs
-
catheters
-
infections
-
A & C only
-
All of the above
Frage 4
Frage
Which of the following are physiologic anticoagulants that oppose thrombosis?
Antworten
-
AT-III
-
Fibrin
-
Protein C
-
A & C only
-
All of the above
Frage 5
Frage
Which of the following are the most common sources for clinically important pulmonary emboli? (select all that apply)
Antworten
-
Subclavian veins
-
Right Atrium/Ventricle
-
Femoral vein
-
Iliac vein
-
Pelvic vein
Frage 6
Frage
Which of the following compose Virchow's Triad:
Antworten
-
Factors in the vessel wall (e.g. tissue damage)
-
Abnormal blood flow (e.g. venous stasis)
-
Abnormal/Hypercoagulable states
-
Abnormal/Hypocoagulable states
-
Abnormal branching of vessels
Frage 7
Frage
Which of the following may cause venous stasis?
Antworten
-
Surgery
-
Congestive Heart Failure
-
Pregnancy
-
Only A & B
-
All of the above
Frage 8
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Which of the following may cause hypercoagubility? (select all that apply)
Frage 9
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Over 95% of pulmonary emboli are thromboemboli.
Frage 10
Frage
Which of the following are NOT true regarding the natural history of a venous thomboembolism?
Antworten
-
Non-extended distal DVTs rarely cause PE
-
80% of symptomatic DVTs have extended into the distal veins
-
60% of pts w/ symptomatic DVTs w/ will have a PE
-
70% of pts with symptomatic PE will have asymptomatic DVTs
-
DVTs most often start in the calf (distal) veins
Frage 11
Frage
Of the following sxs, which are all associated w/ PE, which is the least common?
(choose one)
Antworten
-
Dyspnea
-
Cough
-
Leg Pain/Swelling
-
Pleuritic chest pain
-
Hemoptysis
-
Wheezing
-
Orthopnea
Frage 12
Frage
Which of the following is the most common sign associated with PE?
(found in approximately 54% of PE presentations)
Antworten
-
Tachypnea
-
Calf swelling/tenderness
-
Tachycardia
-
Decreased breath sounds
-
Crackles
Frage 13
Frage
Which of the following is NOT part of the PERC clinical decision tool (i.e. HADCLOTS) used for diagnosing PE?
Antworten
-
Surgery/trauma w/in past 28 days
-
Coughing blood
-
Lower extremity swelling unilaterally
-
O2 Saturation <95%
-
All of the above are associated with PERC
Frage 14
Frage
Which of the following pairs would have the HIGHEST Wells score?
Antworten
-
1) PE most likely dx (on ddx), 2) Hemoptysis
-
1) Clinical signs and sxs of DVT, 2) Immobilization for > 3 consecutive days or surgery in previous 4 weeks
-
1) Previous Dx of PE or DVT, 2) Cancer (tx w/in past 6 mo)
-
1) Tachycardia (>100bpm), 2) Immobilization for > 3 consecutive days or surgery in previous 4 weeks
-
1) PE most likely dx (on ddx), 2) Cancer (tx w/in past 6 mo)
Frage 15
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An EKG & Chest X-ray can be helpful tools in diagnosing a PE.
Frage 16
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Which of the following may be found on a chest x-ray of a pt w/ PE?
(note: these are neither sensitive nor specific findings)
Antworten
-
Decreased vascular markings in an area of lung (i.e. Westermark’s sign)
-
Wedge-shaped infiltrate extending to the pleural surface (i.e. Hampton’s hump)
-
Normal (no abnormal findings)
-
Only A & B
-
All of the above
Frage 17
Frage
Which of the following may be found on an EKG of a pt w/ PE?
(note: these are neither sensitive nor specific findings)
Antworten
-
Ventricular arrhythmias
-
Left bundle branch block
-
S1 Q3 T3 pattern
-
Only A & C
-
All of the above
Frage 18
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Which of the following clinical signs of PE is shown on this x-ray?
Antworten
-
Westermark's sign
-
Hampton's hump
Frage 19
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Which of the following clinical signs of PE is shown on this x-ray?
Antworten
-
Westermark's sign
-
Hampton's hump
Frage 20
Frage
Which of the following is NOT true regarding use of CT angiography in dx of PE?
(select any that apply)
Antworten
-
Bolus radiocontrast injection given intravenously.
-
High speed, multi-slice CT scanner takes thin section images.
-
Excellent definition of main and lobar.
-
May detect central and peripheral emboli.
-
May provide bonus information about the lungs and mediastinal structures.
Frage 21
Frage
CT scanning has excellent (~90%) positive predictive values.
Frage 22
Frage
Pulmonary angiography is considered the "gold standard" for dx of PE.
Frage 23
Frage
Which of the following statements is/are NOT accurate regarding pulmonary angiography.
Antworten
-
Considered the "gold standard" in dx PE
-
Allows measurement of pulmonary artery pressures
-
It is both invasive and expensive
-
Frequently used to confirm dx of PE
-
Requires administration of intravenous radiocontrast
Frage 24
Frage
Which of the following is/are NOT true in regards to V/Q scanning in dx of PE:
(select any that apply)
Antworten
-
perfusion scanning uses venous injection with radiolabeled- macroaggregated albumin (technetium 99)
-
ventilation scanning requires Iinhalation of a gas mixture containing a radiotracer (xenon 133)
-
it is sensitive for decreased flow to areas of the pulmonary vascular bed, but not specific
-
a normal perfusion scan excludes the diagnosis of PE.
-
in PE cases, areas of vascular obstruction should show decreased ventilation but preserved perfusion
Frage 25
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A "high probability" V/Q scan result, coupled with high clinical suspicion, gives a > 95% likelihood of PE.
Frage 26
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A negative (i.e. normal) D-Dimer result may be used to rule-out DVT and PE, regardless of clinical presentation and probability scores.
Frage 27
Frage
Which of the following labs is LEAST helpful in the dx of PE?
Antworten
-
CBC
-
ABG
-
BNP
-
Troponin
-
INR, PTT
Frage 28
Frage
Which of the following labs/results are NOT properly matched, in regards to dx PE.
Antworten
-
ABG: hypoxemia, widened alveolar-arterial gradient, and respiratory alkalosis
-
BNP: may be elevated due to right heart strain
-
Troponin: may be decreased in 30-50% of cases
-
PTT: needed for baseline when considering tx options
Frage 29
Frage
A D-Dimer test could be positive in which of the following cases?
Antworten
-
Pregnancy
-
Infection
-
Post-Op
-
Trauma
-
All of the above
Frage 30
Frage
According to the diagnostic algorithm for pulmonary embolism, if the pt's Wells score exceeds 4, what is the next step?
Frage 31
Frage
According to the diagnostic algorithm for pulmonary embolism, if the pt's Wells score is below 4, what is the next step?
Antworten
-
No treatment (PE dx excluded)
-
D-Dimer to confirm
-
Chest X-ray to confirm
-
Serial Venous Doppler (US) to rule-out DVT
-
Labs to confirm (BNP, LFT, CBC, etc.)
Frage 32
Frage
Small emboli discovered in the course of dx are relatively benign and do not require tx.
Frage 33
Frage
Which three signs/sxs are most indicative of an acute PE?
Frage 34
Frage
Prompt use of heparin in pt's w/ a DVT helps to lyse the clot and reduce mortality.
Frage 35
Frage
Mortality of PE after the initiation of heparin decreases to <5%
Frage 36
Frage
Which of the following anticoagulants is the treatment of choice in pt's w/ a bleeding risk?
Antworten
-
Low molecular weight heparin
-
Unfractionated heparin
-
High molecular weight heparin
-
Fractionated heparin
-
None of the above (Anticoagulants are contraindicated in pt's w/ bleeding risk)
Frage 37
Frage
Which of the following statement is NOT accurate?
Antworten
-
Unfractionated Heparin requires frequent lab monitoring
-
Unfractioned Heparin requires continuous infusion due to a short half-life
-
Unfractionated Heparin is reversible
-
LMW Heparin is administered via intramuscular injections
-
LMW Heparin does not require frequent monitoring and may be managed at home
Frage 38
Frage
Which of the following is NOT true regarding Rivaroxaban & Dabigatran?
Antworten
-
they are oral medications approved by the FDA for the tx of PE
-
their risk of causing bleeding events is comparable or less than that of coumadin
-
they are both reversible
-
neither require close monitoring
-
they are both thrombin inhibitors
Frage 39
Frage
Thrombolytics are only indicated in hemodynamically stable patients.
Frage 40
Frage
Thromolytic tx may cause an intracranial hemorrhage.
Frage 41
Frage
Thrombolyics are typically administered by a vascular surgeon and/or radiologist.
Frage 42
Frage
Which of the following might necessitate the use of an IVC ?
Frage 43
Frage
Which of the following are predictors of poor outcomes for pt's w/ hx of PE? (choose all that apply)
Antworten
-
Hypotension
-
Hypoxemia
-
Coexisting DVT
-
Decreased lactate
-
Decreased WBC
Frage 44
Frage
A resting pulmonary artery pressure of ________ is considered pulmonary hypertension.
Antworten
-
more than 25mmHg
-
more than 35mmHg
-
more than 45mmHg
-
more than 55mmHg
Frage 45
Frage
Pulmonary hypertension may be:
Frage 46
Frage
Pulm. HTN is due to hypoxia and hypoxemia and may be seen in diseases such as COPD.
Frage 47
Frage
An increase in blood flow, such as one experiences while exercising, will cause a proportional increase across the pulmonary vascular bed.
Frage 48
Frage
Which of the following may cause pulm HTN (via chronic hypoxemia): (select all that apply)
Antworten
-
Chronic high altitude
-
COPD
-
Pulmonary fibrosis
-
Obstructive sleep apnea
-
Chronic Asthma
Frage 49
Frage
Which of the following may also cause pulm HTN:
(select all that apply)
Antworten
-
Parasitic infections
-
Recurrent/unresolved PE
-
Cocaine use
-
HIV
-
Syphilis
-
Liver disease
-
Allergies
Frage 50
Frage
Idiopathic pulm HTN is most common in women, ages 20-45 years old, and is due to medial hypertrophy and intimal proliferation and fibrosis.
Frage 51
Frage
Common symptoms of Pulm HTN may include:
(choose all that apply)
Antworten
-
Dyspnea
-
Dysphagia
-
Peripheral edema
-
Syncope
-
Chest pain
Frage 52
Frage
Possible signs of pulm HTN may include:
Antworten
-
Carvahlo's sign
(tricuspid murmur, regurg. w/ inspir.)
-
Prominent pulmonic component of second heart sound
-
Right ventricular (S3) gallop
-
JVD
-
Transient periods of tachycardia
-
Distended spleen
-
Left ventricular hypertrophy
-
Corrigan's pulse
(alternates weak and bounding)
Frage 53
Frage
All of the following are possible lab/diagnostic findings in Pulm HTN, EXCEPT:
Frage 54
Frage
Which of the following are potential treatments for Pulm HTN: (select all that apply)
Frage 55
Frage
Of the vasodilators used to tx pulm HTN, which is the most controversial?
Frage 56
Frage
Which of the following statements is NOT accurate regarding Cor Pulmonale?
Antworten
-
Right ventricular failure due to pulmonary disease
-
Usually accompanied by hypercapnia
-
Most commonly caused by pulm HTN, COPD, or pulm fibrosis
-
Chronic and progressive
Frage 57
Frage
Which are NOT common sxs associated with Cor Pulmonale:
Antworten
-
Cough
-
Swelling of face/neck
-
Cyanosis
-
JVD
-
Dysphagia
-
Gallop S3 heart rhythm
Frage 58
Frage
Common lab findings in Cor Pulmonale include:
Antworten
-
Westermark sign on CXR
-
RAD, RVH on EKG
-
Polycythemia on CBC
-
B & C only
-
All of the above
Frage 59
Frage
All of the following are used to tx Cor Pulmonale EXCEPT:
Frage 60
Frage
This is a rare autoimmune disease that affects the kidneys and lungs, causing necrosis of alveoli and loss of gas exchange.
Antworten
-
Goodpasture's Syndrome
-
Wegener's Granulomatosis
Frage 61
Frage
While Goodpasture's may affect persons of all ages, it is found to be more common in younger males and older females.
Frage 62
Frage
Signs/Sxs that might differentiate Goodpasture's from diseases such as PE and Pulmonary HTN, include:
(select all that apply)
Antworten
-
Hematuria
-
Pallor
-
Weight Loss
-
Myalgia
-
Proteinuria
Frage 63
Frage
Which of the following diagnostics are indicated in a work-up for Goodpasture's syndrome?
(Select all that apply)
Frage 64
Frage
Goodpasture's Syndrome is treated with:
Frage 65
Frage
This rare disease causes "geograpahic" necrosis and granulomatous inflammation of the airways.
Frage 66
Frage
Wegener's granulomatous is believed to be caused by cellular immune processes and may present w/ respiratory and renal involvement.
Frage 67
Frage
Which of the following statements concerning Wegener's granulomatous is FALSE ?
Antworten
-
It is a rare disease
-
Equally prevalent in men and women
-
Typically occurs in the 4th-5th decade of life
-
Is fatal within one year if not treated
-
All of the above statements are TRUE
Frage 68
Frage
This rare disease can cause recurrent sinusitis, chronic ear infections, and a variety of flu-like sxs.
Frage 69
Frage
The work-up for this disease includes a blood test for anti-neutrophil cytoplasmic antibodies.
Frage 70
Frage
While many survivors may be dependent on dialysis, the 5-year survival rate for Wegener's granulomatous is about 70%