Frage 1
Frage
1-the following may be used to assess drug efficacy in the graded dose – response curve :
Antworten
-
A- slope of the curve
-
B- ED50
-
c- Emax
-
D- A&C
Frage 2
Frage
2-atropine is used as pre-anesthetic medication due to all the following except :
Antworten
-
it decreases blood pressure
-
it induces bronchodilatation & stimulates respiration
-
it decreases vomiting
-
it blocks the cardiac muscarinic receptors
Frage 3
Frage
3- the following is NOT an adverse effect of cholinomimetics :
Antworten
-
Bronchospasm
-
Diarrhea
-
Tachycardia
-
aggravate peptic ulcer
Frage 4
Frage
4-treatment of atropine poisoning does not include:
Antworten
-
A- gastric lavage
-
B- neostigmine
-
C- diazepam
-
D- cooling blankets
Frage 5
Frage
5-Important factor\s which may govern diffusion of drugs across cell membranes :
Frage 6
Frage
6- at the end of operation , the action of neuromuscular blocker is reversed by :
Antworten
-
a- atropine preceded by neostigmine
-
b- neostigmine preceded by atropine
-
c- atropine preceded by physostigmine
-
d- physostigmine preceded by atropine
Frage 7
Frage
7-clearance is useful in calculation of :
Antworten
-
a-maintenance doce
-
b-loading dose
-
c- t 1\2
-
d -a&c
Frage 8
Frage
8-Propranolol is contraindicated in all of the following cases except:
Antworten
-
A) Open angle glucoma
-
B) Diabetes Mellitus
-
C) Thyrotoxicosis
-
D) Bronchial asthma
Frage 9
Frage
9-which of the following beta blockers is suitable in patient with open angle glaucoma ?
Antworten
-
a- betoxolol
-
b- bisorolol
-
c- pindolol
-
propranolol
Frage 10
Frage
10- Which of the following drugs inhibit the release of NE :
Antworten
-
A) Guanethedine
-
B) Reserpine
-
C) Metyrosine
-
D) Non of the above
Frage 11
Frage
11- patient with history of sulfonamide hypersesitivity , suffered head injury with brain edema , which of the following combinations is best for him ?
Antworten
-
a- acetazolamide & mannitol
-
b- metolazone & mannitol
-
c- dexamethazone & frusemide
-
d- dexamethazone & mannitol
Frage 12
Frage
12- furosemide is useful for treatment of the following conditions except :
Frage 13
Frage
13-antihypertensive effect of frusemide is decreased by :
Antworten
-
a- NSAIDs
-
b- spironolactone
-
c- corticosteroids
-
d- a& c
Frage 14
Frage
14-The following diuretics are secreted through the renal tubules except:
Antworten
-
a- Triamterene
-
b- Spironolactone
-
c-Hydrochlorothiazide
-
d- Frusemide
Frage 15
Frage
15- uses of acetazolamide include all the following except :
Antworten
-
a- urinary calcium phosphate stones
-
b- emphysema & high altitude sickness
-
c- to alkalinize urine for excretion of salicylates
-
d- to alkalinize urine for excretion of barbiturates
Frage 16
Frage
16- ACEIs have the following advantages except :
Antworten
-
a- they induce no change in heart rate
-
b- they preserve renal function
-
c- they induce no change in k level
-
d- they reduce cardiovascular mortality
Frage 17
Frage
17- A nitric oxide donor that may induce cyanide toxicity :
Antworten
-
a- nitrates
-
b- nitroprusside
-
c- nicardipine
-
d- A&B
Frage 18
Frage
18- A hypertensive patient with angina should not be given :
Antworten
-
a-pindolol
-
b- bisoprolol
-
c- amlodipine
-
d- metoprolol
Frage 19
Frage
19- used with vasodilators to counteract the reflex tachycardia :
Antworten
-
a- captopril
-
b- methyldopa
-
c- bisoprolol
-
d- pindolol
Frage 20
Frage
20- in congestive heart failure , the following drugs act directly on the myocardium increasing the cardic output except :
Antworten
-
a- captopril
-
b- digoxin
-
c- dopamine
-
d- dobutamine
Frage 21
Frage
21-A drug used to terminate an attack of paroxysmal supraventricular tachycardia but may induce bronchospasm :
Antworten
-
a- lidocaine
-
b-adenosine
-
c- verapamil
-
d- diltiazem
Frage 22
Frage
22- all the following decrease mortality in HF except :
Antworten
-
a- metoprolol
-
b-bisoprolol
-
c- carvedilol
-
d- pindolol
Frage 23
Frage
23-A pregnant asthmatic hypertensive patient should NOT receive :
Antworten
-
a- candesartan
-
b- labetalol
-
c- thiazides
-
d- all the above
Frage 24
Frage
24- In management of digitalis induced bradyarrhythmia the following is (are) true :
Antworten
-
a- KCL should not be administered
-
b- atropine should be administered
-
c- lidocaine should be administered
-
d- A&B
Frage 25
Frage
25- candesartan has the following advantages over lisinopril EXCEPT :
Antworten
-
a- no bradykinin production thus no risk of cough
-
b- antagonizes AG II formed by ACE & non- ACE pathways
-
c- no hormonal "escape " seen with prolonged ACEIs therapy
-
d- less teratogenic
Frage 26
Frage
26- which one of the following is adirect inhibitor of factor Xa ?
Antworten
-
a- dalteparin
-
b- heparin
-
c- rivaroxaban
-
d- fondaparinux
Frage 27
Frage
27- all the following decrease the action of warfarin except :
Antworten
-
a- erythromycin
-
b- vit K
-
c- oral contraceptives
-
d- rifampicin
Frage 28
Frage
28- which of the following is long acting & can be given by single I.V bolus :
Antworten
-
a- streptokinase
-
b- tenecteplase
-
c- urokinase
-
d- all of the above
Frage 29
Frage
29- folic acid deficiency is associated with the use of :
Antworten
-
a- methotrexate
-
b- trimethoprim
-
c- metronidazole
-
d- A&B
Frage 30
Frage
30- given that normal Hb=14gm/ dl , which of the following the following is the parentral iron dose required to correct anemia & replenish stores for a female with Hb=4 gm / dl :
Antworten
-
a- 100 gm
-
b- 10 gm
-
c- 5 gm
-
d- 2.5 gm