Zusammenfassung der Ressource
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Which blood components make up haemostatic mechanisms?
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Platelets
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Vascular epithelium
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Fibrinolysis
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RBC's
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WBC's
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Platelets contain granules
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Name two traits of platelets
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What cells produce platelets (4000 from each cell)?
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Megakaryocytes
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Myeloblasts
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Lymphoblasts
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The normal platelet range is 150-400 x10^9/l
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Once collagen is exposed, what binds to it?
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Van Willibrown Factor
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Factor V
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Factor III
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De Montfort Factor
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Platelets bind to _ Factor and release
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ADP
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Thromborin A2
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Thrombulin
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ATP
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A FBC and film exclude drugs/diseases that cause platelet disorders
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What symptoms suggest platelet failure?
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A child with a platelet disorder is most likely to have aquired it
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How does the Platelet Function Analyser work?
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Forces blood through a membrane with a high shear rate and tests clotting time
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Forces blood into a medium high in collage and tests clotting time
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Forces blood through damaged tubes lined with fibrinogen and tests clotting time
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What causes petechiae?
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Bleeding time is rarely done, as it involves damaging the patient further
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In an aggregation panel, exposed, concentrated platelets are exposed compared to what?
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Which of the following hereditary platelet disorders don't have reduced aggregation with Ristocetin?
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Only Van Willebrowns disorder doesn't involve missing glycoproteins
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Which of the following foods don't effect clotting?
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Bananas
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Peppers
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Onions
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Garlic
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Name a drug that can reduce blood clotting
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Aspirin
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Calnexin
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Ibruprofen
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Myeloproliferative- where excess cells are poduced by the bone marrow