514671
Frage 1
Frage
Which of the following is NOT a major mast cell mediator?
Antworten
-
Heparin
-
Arachadonic acid
-
Platelet activating factor
-
Neutrophilic chemotactic factor
-
Lymphocytic chemotactic factor
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Serine proteases
Frage 2
Frage
Which of the following are effects of histamine? Check all that apply.
Antworten
-
Stimulates nitric oxide production (potent vasodilator)
-
Enhances leukocyte chemotaxis
-
Produces arachadonic acid metabolites
-
Stimulates smooth muscle contraction (bronchi, small intestines, pulmonary vasoconstriction)
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Causes decreased vascular permeability
Frage 3
Frage
Leukotrienes are metabolites of arachadonic acid that are potent bronchoconstrictors.
Antworten
- True
- False
Frage 4
Frage
Which of the following pairings is INCORRECT?
Antworten
-
Serine proteases- destroy nearby cells and activate complement
-
Kinins- stimulate pain receptors
-
Cytokines- regulate storage and release of vasoactive mediators
-
Heparin- acts as anticoagulant
Frage 5
Frage
Generally, the onset of anaphylaxis is not related to severity of signs.
Antworten
- True
- False
Frage 6
Frage
Localized anaphylaxis has evidence of generalized mediator release restricted to cutaneous findings alone. Which of the following is NOT one of these findings?
Antworten
-
Erythema
-
Pruritis
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Urticaria
-
Angioedema
-
These are all appropriate cutaneous findings, Karah. Get it together!
Frage 7
Frage
Which of the following are true regarding epinephrine for systemic anaphylaxis? Check all that apply.
Antworten
-
Blocks effects of mediators
-
Reduces further mast cell degranulation
-
Increases cardiac output
-
Promotes bronhoconstriction
-
Peripheral vasodilation
-
IV dose of 1 mg/ml concentration is 0.05-0.1 ml/10 lbs
Frage 8
Frage
When treating anaphylaxis with crystalloid IV fluids it is important that systolic blood pressure is maintained at >80 mmHg.
Antworten
- True
- False
Frage 9
Frage
Which of the following is the anti-inflammatory dose of dexamethasone SP for treatment of anaphylaxis?
Antworten
-
0.1-0.2 mg/kg IV
-
0.5-1 mg/kg IV
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0.1-0.2 mg/kg IM
-
0.5-1 mg/kg IM
Frage 10
Frage
The IM dose of diphenhydramine for systemic anaphylaxis is 1-2 mg/kg.
Antworten
- True
- False
Frage 11
Frage
What drug can we use to manage persistent bradycardia with systemic anaphylaxis?
Antworten
-
Atropine, 0.02-0.04 mg/kg IV, IM
-
Atropine, 0.2-0.4 mg/kg IV, IM
-
Dobutamine, 5-10 mcg/kg/min IV (constant rate infusion)
-
Dobutamine, 0.5-1 mcg/kg/min IV (constant rate infusion)
Frage 12
Frage
Aminophylline/theophyylline is a bronchodilator given IM or IV (slowly) at 4-8 mg/kg.
Antworten
- True
- False
Frage 13
Frage
What is the dose for oral diphenhydramine for treatment of localized anaphylaxis?
Antworten
-
1 mg/lb q 8 hrs until all signs are clear
-
1 mg/kg q 8 hrs until all signs are clear
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