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Membrane potential operated channels are
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Striated muscle are structure bases of
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Muscle extraction is possible when
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Action potential is shape depends on
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Action potential is
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Elevation of calcium concentration is for
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Average power of contraction of smooth muscle per unit cross section
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Actin and myosin are in [blank_start]cellular fiber network[blank_end]
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Smooth muscle cells are organised in [blank_start]bundles[blank_end] in strong parallel layers or spherical structures
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Antworten
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tubular links between cells
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ionized groove upon the membrane
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protein structures in membranes through which ions pass
Frage 12
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Ion channels conductivity during the action potential
Frage 13
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On the border water-air (the free surface of the water) lipids from
Frage 14
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In stationary state the membrane potential
Frage 15
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Both smooth muscle contractions and skeletal muscle contractions involve thin (actin) filament over the thick (myosin) filaments
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In smooth muscle contraction, the majority of calcium (Ca2+) needed for contraction enters from extracellular fluid.
Frage 17
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Troponin and tropomyosin are attached to thick filaments of smooth muscle cells
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Myosin of the thick filaments of smooth muscle cells must be phosphorylated in order to bind of the thin filaments
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Nor-epinephrine released from sympathetic nerve terminals in the heart cause a decrease in the pacemaker activity.
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The rapid upstoke (phase 0) of actin potentials in ventricular and atrial myocytes results from opening of Ca2+ channels.
Frage 21
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Thick filaments are composed of myosin and thin filaments are primarily composed of actin.
Frage 22
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Tropomyosin binds Ca2+ causing a conformational change that causes troponin to uncover binding sites on actin for crossbridge attachment.
Frage 23
Antworten
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Calcium (Ca2+) channel blocker
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Sodium (Na+) channel blocker
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Potassium (K+) channel blocker
Frage 24
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Tetraethylammonium is a blocker for which channel?
Antworten
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Calcium (Ca2+) channel
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Sodium (Na+) channel
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Potassium (K+) channel
Frage 25
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Calcium (Ca2+) channel blocker
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Sodium (Na+) channel blocker
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Potassium (K+) channel blocker
Frage 26
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Which is not a type/class of carrier protein?
Antworten
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Uniport
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Symport
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Antiport
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Microport
Frage 27
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Ionophores have following action except
Frage 28
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Diffusion through a semi-permeable membrane with different permeabilities for different substance is called:
Antworten
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Tran-Diffusion
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Filtration
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Osmosis
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Diffusion
Frage 29
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The pressure that would have to be applied to a pure solvent to prevent it from passing into a given solution by osmosis
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Osmotic Pressure
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Filtration Pressure
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Osmotic Stability
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Movement of liquid across a semipermeable membrane under hydrostatic pressure is called
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Filtration
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Hydrostatic Diffusion
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Osmosis
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None of these
Frage 31
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GLUT1 and Ionophores valiomycin are examples of
Frage 32
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Antiport is best described by
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Carrier protein binds one solutes and transports it across the membrane
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Carrier protein binds two different solutes and transport them together across the membrane
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A substrate binds and is transported across the membrane then another substrate binds and is transported in the other direction
Frage 33
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A factors that does NOT affect rate of facilitated diffusion:
Antworten
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Concentration gradient across the membrane
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Amount of carrier proteins available
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Speed of carrier and substrate attachment
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How fast the protein changes shape after attachment
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Mean Molecular Velocity
Frage 34
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Which of these is not a type of ion channel?
Frage 35
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Which of this is not a class of ATPase
Antworten
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P-Type
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F-Type
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V-Type
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L-Type
Frage 36
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Which statement is incorrect?
Antworten
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P-type- transport Na+, K+, Ca2+ through plasma membrane and in doing so they are phosphorylated
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F-type- found in mitochondria where they are the prime producers of ATP by using the proton gradient generated by oxidative phosphorylation
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V-type- only found in plant cells, catalysing ATP hydrolysis to transport solutes
Frage 37
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The downhill (along concentration Gradient) movement of one species driving the uphill (against concentration Gradient) movement of another where metabolic energy is not utilised directly is called
Frage 38
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Which part of the sodium-potassium pump (Na=/K+ ATPase) has an ATP binding site and 3 other sites which have a high affinity for Na+ ion
Frage 39
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Resting Potential
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Depolarization
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Repolarization
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Hyperpolarization
Frage 40
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The resting potential can be changed by chemical, mechanical or electrical stimulus
Frage 41
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No refractory period is associated with graded potentials.
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If the membrane potential is changed slowly, the electrical current can pass without action potential needing to be initiated.
This phenomena is known as
Antworten
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Accommodation
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Action Potential
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Electronic Potential
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None of these
Frage 44
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Fill in the gaps: (symbols like K+ /Na+/Ca2+ are used instead of word)
Phase 0: Rapid depolarization: [blank_start]increased[blank_end] Na+ and [blank_start]decreased[blank_end] K+ conductances
Phase 1: Initial re polarization: decreased [blank_start]Na+[blank_end] and increased [blank_start]K+[blank_end] conductances
Phase 2: [blank_start]Plateau phase[blank_end]: increased [blank_start]Ca2+[blank_end] conductance
Phase 3: Re-polarization: increased [blank_start]K+[blank_end] and decreased [blank_start]Ca2+[blank_end] conductances
Phase 4:[blank_start]Resting potential[blank_end]: [blank_start]increased[blank_end] [blank_start]K+[blank_end] and [blank_start]decreased[blank_end] Na+ and [blank_start]decreased[blank_end] Ca2+ conductance
Antworten
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increased
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decreased
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Plateau phase
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Na+
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K+
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Ca2+
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K+
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decreased
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Resting potential
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increased
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decreased
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K+
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Ca2+
Frage 45
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What results in a decrease of AP amplitude and depolarization block therefore the heart stops in diastole?
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Increased sodium (Na+) extracellularly
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Increased Potassium (K+) extracellularly
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Decreased Potassium (K+) extracellularly
Frage 46
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What results in shortening of the refractory period therefore a defibrilation risk?
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Increased extracellular potassium (K+)
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Decreased extracellular potassium (K+)
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Increased extracellular calcium (Ca+)
Frage 47
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What would cause a sudden decrease of AP depolarization phase and its duration resulting in cells becoming unexcitable?
Antworten
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Increased extracellular potassium (K+)
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Increased extracellular sodium (Na+)
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Decreased extracellular sodium (Na+)
Frage 48
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Which of these statements are true
More than one correct ans.
Antworten
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Z line – Where the myosin filaments are anchored
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M line – Where the myosin filaments are anchored
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A band – The length of a myosin filament, may contain overlapping actin filaments
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I band – Contains only actin filaments
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H Zone- Contains only myosin filaments
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All are true
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None are true
Frage 49
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Which is true for Troponin T
Antworten
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Connect troponin to Tropomyosin
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Suppress interaction between actin and myosin in absence of Ca2+
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Reversible connection with Ca2+ when concentration of Ca2+ is high enough
Frage 50
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Which best describes Isometric muscle contraction?
Antworten
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Muscles shortens in length in relationship to the production of movement (i.e. push ups)
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Muscle length remains the same, no movement occurs but the force (muscle tension) is increased above tonic levels to resist gravity or other forces i.e. holding a shopping bag
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Contraction against increasing force
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[blank_start]Isotonic[blank_end]: Muscles shortens in length in relationship to the production of movement (i.e. push ups)
[blank_start]Isometric[blank_end]: Muscle length remains the same, no movement occurs but the force (muscle tension) is increased above tonic levels to resist gravity or other forces i.e. holding a shopping bag
[blank_start]Auxotonic[blank_end]: Contraction against increasing force
Antworten
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Isotonic
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Isometric
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Auxotonic
Frage 52
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Force<load therefore axotonic/eccentric contraction speed of contraction (V) is
Frage 53
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Electromechanical connection is the dependence between membrane potential and
Frage 54
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How long is the latent period between stimuli and muscle contraction
Antworten
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2-3 ms
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2-3 sec
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No latent period
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12-13 ms