6812977
Frage 1
Frage
Which options are primary lymphoid organs?
Antworten
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Thymus
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Bone marrow
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Spleen
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Peyer's patches
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MALT
Frage 2
Frage
Which options are secondary lymphoid organs?
Antworten
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MALT
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Spleen
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Lymph nodes
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Thymus
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Bone marrow
Frage 3
Frage
Dendritic cells are derived from lymphoid and myeloid precursors.
Antworten
- True
- False
Frage 4
Frage
Platelets are derived directly from pluripotent stem cells.
Antworten
- True
- False
Frage 5
Frage
Which options do not express MHC Class 1?
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Red blood cells
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Platelets
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Neutrophils
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B cells
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T cells
Frage 6
Frage
Naive B cells are derived from the
Antworten
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Bone marrow
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Thymus
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Spleen
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MALT
Frage 7
Frage
CD4+ T cells recognise
Antworten
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MHC Class 1
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MHC Class 2
Frage 8
Frage
CD8+ T cells recognise
Antworten
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MHC Class 1
-
MHC Class 2
Frage 9
Frage
CD16 and CD56 are both found on
Antworten
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NK cells
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Macrophages
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B cells
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T cells
Frage 10
Frage
All leukocytes express
Antworten
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CD45
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CD19
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CD68
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CD59
Frage 11
Frage
The most abundant leukocyte in circulation are...
Antworten
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Neutrophils
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Macrophages
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B cells
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CD8+ T cells
Frage 12
Frage
Monocytes and Macrophages help to produce components involved in the complement system
Antworten
- True
- False
Frage 13
Frage
Macrophages are able to present antigens on their surface
Antworten
- True
- False
Frage 14
Frage
Monocytes have CD.....
Antworten
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14
-
56
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16
-
15
Frage 15
Frage
During phagocytosis, fusion of the lysosome and phagosome leads to production of...
Antworten
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Phagolysosome
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Early endosome
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Endophagosome
Frage 16
Frage
Which granulocytes have major basic protein in their granules?
Antworten
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Eosinophils
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Basophils
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Neutrophils
Frage 17
Frage
Which granulocytes have lactoferrin in their granules?
Antworten
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Neutrophils
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Eosinophils
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Basophils
Frage 18
Frage
Which granulocytes do not have histamine in their granules?
Antworten
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Eosinophils
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Neutrophils
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Basophils
Frage 19
Frage
Which granulocytes have chondroitin sulphate in their granules?
Antworten
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Neutrophils
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Eosinophils
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Basophils
Frage 20
Frage
Which of these are reactive oxygen species?
Antworten
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Hypochlorous acid
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Hydrogen peroxide
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Superoxide
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Water
Frage 21
Frage
The only antimicrobial peptides that macrophages use are...
Antworten
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Cathelicidins
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Azurocidin
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Defensins
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Histatins
Frage 22
Frage
Acidification by neutrophils or macrophages is...
Antworten
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Bacteriocidal
-
Bacteriostatic
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Can be both
Frage 23
Frage
Both macrophages and neutrophils produce ROS's.
Antworten
- True
- False
Frage 24
Frage
Both macrophages and neutrophils produce NETs.
Antworten
- True
- False
Frage 25
Frage
The most potent antigen present cell is...
Antworten
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Dendritic cells
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Macrophages
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Monocytes
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B cells
Frage 26
Antworten
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platelet
-
ctivating
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fibrinogen
-
ytokines
-
C3b
Frage 27
Frage
Most T cells are...
Antworten
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CD4 positive but CD8 negative
-
CD4 positive and CD8 positive
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CD8 positive but CD4 negative
Frage 28
Frage
Which cytokine results in a T cell receptor being produced on an immature T cell?
Antworten
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IL-7
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IL-10
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GM-CSF
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TNF-a
Frage 29
Frage
Self molecules are said to induce...
Antworten
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Tolerance
-
Multi-specificity
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Immunogenicity
Frage 30
Frage
What is negative selection?
Antworten
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T cells with a high affinity for self antigens are killed by apoptosis
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T cells with a high avidity for self antigens are killed by apoptosis
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T cells with a low affinity for self antigens are killed by apoptosis
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T cells with a low affinity for self antigens are allowed to mature
Frage 31
Frage
What is positive selection?
Antworten
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T cells with a low affinity for self antigens are allowed to mature
-
T cells with a high affinity for self antigens are allowed to mature
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T cells with a high affinity for self antigens are killed off by apoptosis
-
T cells with a low affinity for self antigens are killed off by apoptosis
Frage 32
Frage
The majority of T cells do not make it through negative selection.
Antworten
- True
- False
Frage 33
Frage
T cells without any stimulation also die off.
Antworten
- True
- False
Frage 34
Frage
What CD do T regulatory cells have?
Antworten
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4
-
19
-
8
Frage 35
Frage
Which cells do TH1 helper cells activate?
Antworten
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Macrophages
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B cells
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Any nucleated cell
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Stromal cells
Frage 36
Frage
Which cells do TH2 helper cells activate?
Antworten
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B cells
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Macrophages
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T cells
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Stromal cells
Frage 37
Frage
Which cells do TH17 helper cells activate?
Antworten
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Stromal cells
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B cells
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Macrophages
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T cells
Frage 38
Frage
What is the main effect of T reg cells?
Antworten
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Recruiting neutrophils
-
Activating macrophages
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Triggering B cell proliferation and antibody secretion
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Inhibition of immune response
Frage 39
Frage
What is the main effect of TH2 cells?
Antworten
-
Recruiting neutrophils
-
Activating macrophages
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Triggering B cell proliferation and antibody secretion
-
Inhibition of immune response
Frage 40
Frage
What is the main effect of TH1 cells?
Antworten
-
Recruiting neutrophils
-
Activating macrophages
-
Triggering B cell proliferation and antibody secretion
-
Inhibition of immune response
Frage 41
Frage
What is the main effect of TH17 cells?
Antworten
-
Recruiting neutrophils
-
Activating macrophages
-
Triggering B cell proliferation and antibody secretion
-
Inhibition of immune response
Frage 42
Frage
Which cytokine(s) tend to be released by TH17 cells?
Antworten
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IL-7
-
IL-17
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TGF-beta
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IL-10
Frage 43
Frage
Which cytokine(s) tend to be released by TH1 cells?
Antworten
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IL-7
-
IL-10
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IFN-gamma
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TGF-beta
Frage 44
Frage
Which cytokine(s) tend to be released by TH2 cells?
Antworten
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IL-4
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TNF-a
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TNF-b
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PGD2
Frage 45
Frage
Which cytokine(s) tend to be released by CD8+ cells?
Antworten
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IFN-gamma
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TNF-a
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TGF-b
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IL-4
Frage 46
Frage
What feature on T cells helps to induce proliferation B cells?
Antworten
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CD40
-
CD40 Ligand
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mIgM
-
CD45
Frage 47
Frage
B cells have complement receptors.
Antworten
- True
- False
Frage 48
Frage
As well as perforin and granzyme to kill target cells, NK cells have...
Antworten
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NK Cytotoxic factor
-
CD40 Ligand
-
Major basic protein
-
Lyophosphatase
Frage 49
Frage
Interferon gamma is produced by NK cells - what is its function?
Antworten
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Activate phagocytes
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Activates B cells
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Induces proliferation of T cells
Frage 50
Frage
NK cells have a T cell receptor.
Antworten
- True
- False
Frage 51
Frage
T cells are the most abundant lymphocytes.
Antworten
- True
- False
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