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HIV and AIDS has a natural reservoir in monkeys. This virus most likely made the jump from monkeys to humans when:
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Humans engaged in sexual behaviour with monkeys.
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Humans started hunting monkeys.
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Scientists started on careless research with monkeys.
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Zoos were created, increasing monkey-human contact.
Frage 2
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A doctor who noticed HIV starting to emerge.
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The doctor responsible for the outbreak of HIV.
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The first HIV patient in the US.
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A field doctor in Congo.
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In 1981, with the emergence of HIV and AIDS, many young, homosexual males started coming down with Kaposi's sarcoma. Kaposi's sarcoma is:
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An extremely lethal brain cancer.
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A potentially lethal cancer of blood vessels.
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A completely benign skin cancer.
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A benign cancer in the lungs and throat.
Frage 4
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In 1981, these two diseases were the most common indicators of people who had come down with HIV.
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Kaposi's sarcoma and PCP.
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PCP and pneumonia.
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Kaposi's sarcoma and small pox.
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Kaposi's sarcoma and measles.
Frage 5
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Which of the following are ways HIV and AIDS can be transferred? Check ALL that apply.
Frage 6
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Gaëtan Dugas was written about in the book 'And The Band Played On: Politics, People and the AIDS Epidemic'. He was an important figure in AIDS research because:
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For a long time he was mistakenly considered to be the index patient for AIDS.
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He was a prominent author who wrote about AIDS.
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He created to the first name of HIV, 'GRIDS'.
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He was a primary cause in the intravenous drug use transmission of HIV.
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In response to HIV, the immune system is attacked, and antibodies cannot be generated quickly. This is why from 3 weeks to 6 months an antibody test on an infected person might mistakenly turn up a:
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false positive.
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false negative.
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true positive.
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true negative.
Frage 8
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The first symptoms of HIV within the first two weeks commonly appears to be:
Frage 9
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If you want the most accurate results for if you have HIV, you should get an antibody test.
Frage 10
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The most common way for HIV to be transferred between mother and child is:
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Transplacentally in the womb.
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During the birth process.
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Postnatal breast feeding.
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Upon conception.
Frage 11
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Giving an HIV-positive mother a dose of HIV drugs before birth and a dose to the child up to 72 hours after birth can greatly reduce likelihood of permanent HIV infection in the child.
Frage 12
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Approximately what percent of all people living with AIDS live in Sub-Saharan Africa?
Frage 13
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In HIV, the genome is contained in:
Frage 14
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In order to make DNA out of their RNA, retroviruses like HIV use an enzyme called:
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Reverse transcriptase.
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RNAstase.
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Genome Inverstil.
Frage 15
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In viral cell attachment, there are multiple steps. First, [blank_start]GP120[blank_end] must bind to two receptors to get into the host cell. Once in the cell, the virus' [blank_start]reverse transcriptase[blank_end] turns RNA into DNA. The enzyme [blank_start]integrase[blank_end] enables integration of viral DNA into cellular DNA. After this, the enzyme [blank_start]protease[blank_end] cleaves polypeptides into functional [blank_start]HIV-1 proteins[blank_end]. Lastly, the virus [blank_start]buds[blank_end] from the cell wall and leaves to infect other cells.
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GP120
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reverse transcriptase
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integrase
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protease
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buds
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HIV-1 proteins
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mRNA
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immune system
Frage 16
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For HIV Chemotherapy, one of the treatments is HAART. HAART stands for:
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Highly Active Anti Retroviral Therapy.
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HIV Analysis And Removal Therapy.
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Heavily Aggressive Antigen Resource Treatment.
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Heat Activated Aorta Resonance Treatment.
Frage 17
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Inhibitors of viral enzymes can be competitive or non-competitive. With competitive inhibitors, the inhibitor:
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Leaves substrate in the enzyme, preventing other substrate (the virus) from binding.
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Prevent integrase from inserting viral DNA into cellular DNA.
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Coats the outside of the cell, preventing the virus from budding out of the cell.
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Fights the viral enzymes directly.
Frage 18
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The HAART treatment commonly helps patients survive:
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To their mid 30s.
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To the life expectancy they would have without HIV.
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10 years longer than they would have without HAART.
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Forever. HAART patients commonly become immortal.
Frage 19
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All cells will make viruses once they are infected with HIV.
Frage 20
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AZT is a competitive inhibitor for HIV. It stops reverse transcriptase from making viral DNA by:
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Integrating into the chain without a hydroxyl group, terminating the chain.
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Taking apart the reverse transcriptase.
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Preventing it from getting the necessary materials to make the DNA.
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Cutting the RNA into segments.
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A similar competitive inhibitor to AZT, Lamivudine was initially used for HIV patients, but found to be more effective combating:
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Pertussis.
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Hepatitis B.
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Polio.
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AIDS.
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This drug is used for best prevention of mother to child HIV transmission, as it is very safe:
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Nevirapine.
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Lamivudine.
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AZT.
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Integrase.
Frage 23
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In America, these are the proportion of HIV infected individuals at each stage of care.
Of all patients with HIV,
80% - [blank_start]Are diagnosed.[blank_end]
62% - [blank_start]Are linked to HIV care.[blank_end]
41% - [blank_start]Are retained in HIV care.[blank_end]
36% - [blank_start]Are on antiretroviral therapy.[blank_end]
28% - [blank_start]Have a suppressed viral load.[blank_end]
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Are diagnosed.
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Are linked to HIV care.
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Are retained in HIV care.
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Are on antiretroviral therapy.
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Have a suppressed viral load.
Frage 24
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HAART requires 5 years of continuous viral treatment with full adherence to eliminate HIV in the body.
Frage 25
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During HAART treatment, it's possible for patients to experience ARV (anti-retroviral) failure. This is most commonly caused by:
Frage 26
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To enter the Helper T cell, the HIV receptor must bind to two receptors:
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First, CD4, then CCR5.
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First, CCR5, then CD4.
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First, to the nucleus, then to the plasma membrane.
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First to the CD4, then to the genome.
Frage 27
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Timmothy Brown is a famous patient in HIV treatment because:
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After a bone marrow transplant, he became HIV negative.
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He was the index case for HIV.
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His tears could heal other HIV patients.
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He survived to over 100 without any treatment whatsoever.
Frage 28
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HIV most commonly attacks Helper T cells. This is is a problem because:
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Helper T cells are high on the immune system hierarchy, and T and B cells depend on them.
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Helper T cells are very low on the immune system hierarchy, so it's not that much of a problem.
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Helper T cells are at the top of the immune system hierarchy, and everything depends on them.
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Helper T cells are coated with CCR5, an important receptor that will lead to death if suppressed.
Frage 29
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HIV can infect the brain if it's transported into it by this cell, which has clearance into the brain:
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Helper T Cells.
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Macrophages.
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Memory B Cells.
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Plasma Cells.
Frage 30
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In HIV patients, the relationship between helper T cells and antibodies is commonly as follows:
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Antibody levels rise, and helper T cell levels rise.
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Antibody levels rise, and helper T cell levels lower.
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Antibody levels lower, and helper T cell levels lower.
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Antibody levels lower, and helper T cell levels rise.