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Impaired Production of water fluid from the airway epithelium is known as [blank_start]cystic fibrosis[blank_end].
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The thorax is a closed compartment bounded at the neck by muscles and connective tissue and completely separated from the abdomen by a large, dome shaped sheet of skeletal muscle called the [blank_start]diaphragm[blank_end].
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Type II alveolar cells secrete a detergent like substance known as [blank_start]surfactant[blank_end] that is important for preventing the collapse of the alveoli.
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Dalton’s Law of Partial Pressures states that the partial pressure of each gas is directly proportional to its percentage in the mixture. Nitrogen is commonly represented at [blank_start]78.8[blank_end] % of the total mixture.
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In a normal situation the alveoli contain a higher concentration of [blank_start]carbon dioxide[blank_end] and water vapor in comparison to the atmosphere.
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Alveoli enable extreme increase in [blank_start]surface area[blank_end] and a [blank_start]short[blank_end] diffusion path to [blank_start]enhance[blank_end] diffusive gas exchange.
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surface area
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short
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enhance
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Respiratory pressure is always described relative to [blank_start]atmospheric pressure[blank_end].
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Pneumothorax is caused by the equalization of [blank_start]intrapleural[blank_end] pressure with intrapulmonary pressure.
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[blank_start]Intrapleural pressure[blank_end] is what keeps the lungs open and not flattened.
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Boyles Law is the relationship between the [blank_start]pressure[blank_end] and volume of gases at a constant temperature.
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In a healthy individual, energy is only required for expiration while [blank_start]exercising[blank_end].
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The [blank_start]phrenic nerve[blank_end] is responsible for stimulating the diaphragm, which causes it to move inferiorly as it contracts during [blank_start]inspiration[blank_end].
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phrenic nerve
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inspiration
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Pulmonary Fibrosis (pictured) is a disease where the normal tissues in the lungs are replaced with [blank_start]scar tissue[blank_end], which is less [blank_start]elastic[blank_end]; it also increases the [blank_start]thickness[blank_end] of the alveoli.
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scar tissue
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elastic
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thickness
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Lung compliance (shown in the graph) is determined by lung volume and [blank_start]transpulmonary pressure[blank_end].
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Two ways to treat infant respiratory distress syndrome is with [blank_start]synthetic surfactant[blank_end] and putting the infant on a [blank_start]ventilator[blank_end]. Without these, the infant’s lungs will [blank_start]collapse[blank_end] at every breath.
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synthetic surfactant
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ventilator
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collapse
Frage 16
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Flow, [blank_start]pressure[blank_end] and resistance are all physical factors that influence lung ventilation.
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The amount of gas flowing into and out of the [blank_start]alveoli[blank_end] is directly proportional to change in [blank_start]pressure[blank_end].
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Because of the bronchoconstriction in asthmatic individuals, there is a [blank_start]2[blank_end] times reduction in radius, resulting in a [blank_start]16[blank_end] times reduction in flow.
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Carbon dioxide can be transported in the blood by dissolving in plasma, chemically bound to [blank_start]hemoglobin[blank_end] and as a bicarbonate ion in plasma.
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The respiratory system is one of [blank_start]2[blank_end] major buffering systems in the body, by regulating [blank_start]carbon dioxide[blank_end].
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[blank_start]Dyspnea[blank_end], difficult or labored breathing. is a symptom experienced by both those who have asthma and chronic obstructive pulmonary disease.
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High fever, night sweats, and weight loss are all symptoms of [blank_start]tuberculosis[blank_end].
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The [blank_start]concentration difference[blank_end] and [blank_start]barrier thickness[blank_end] or diffusion path are both needed to calculate the diffusion rate using Fick’s Diffusion Equation.
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concentration difference
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barrier thickness
Frage 24
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[blank_start]Hypoxemia[blank_end] is a type of hypoxia caused by a reduced level of oxygen in the blood.
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CO2 is [blank_start]more[blank_end] soluble than H2O
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The partial pressure of CO2 in tissue is [blank_start]higher[blank_end] than the partial pressure of CO2 in the bloodstream
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A reduced alveolar ventilation causes the partial pressure of carbon dioxide to [blank_start]increase[blank_end] and the partial pressure of oxygen to [blank_start]decrease[blank_end], which prompt pulmonary arterioles to [blank_start]constrict[blank_end].
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increase
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decrease
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constrict
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[blank_start]Ischemic[blank_end] hypoxia occurs when blood flow is blocked.
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The most common way that carbon dioxide is carried in the blood is via the [blank_start]bicarbonate buffer system[blank_end].
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In the bicarbonate buffer system, when a bicarbonate ion moves out a red blood cell, [blank_start]a chloride ion[blank_end] moves into the red blood cell.
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Slow, shallow breathing [blank_start]increases[blank_end] the concentration of CO2 in the blood.
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The ventral respiratory group of the medulla has [blank_start]rhythm generating neurons[blank_end].
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[blank_start]Ischemic[blank_end] hypoxia occurs when blood flow is blocked.
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The most common way that carbon dioxide is carried in the blood is via the [blank_start]bicarbonate buffer system[blank_end].
Frage 35
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In the bicarbonate buffer system, when a bicarbonate ion moves out a red blood cell, [blank_start]a chloride ion[blank_end] moves into the red blood cell.
Frage 36
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Slow, shallow breathing [blank_start]increases[blank_end] the concentration of CO2 in the blood.
Frage 37
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The ventral respiratory group of the medulla has [blank_start]rhythm generating neurons[blank_end].
Frage 38
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Muscle glycogen depletion, known colloquially as [blank_start]hitting the wall[blank_end] occurs when the shift to lipid oxidation fails to meet ATP demand, despite adequate O2 supply to the mitochondria. (Lecture 4)
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[blank_start]Diastolic blood pressure[blank_end] remains the same during exercise.
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Cardiac output in a trained individual is [blank_start]the same as[blank_end] cardiac output in an untrained individual.
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The scalenes, sternocleidomastoid, and erector spinae muscles are examples of [blank_start]inspiratory muscles[blank_end].
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[blank_start]Aerobic scope[blank_end] is VO2max / resting metabolic rate.
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Cost of transport [blank_start]does not change[blank_end] with training.
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Cost of transport [blank_start]decreases[blank_end] with % body fat and [blank_start]decreases[blank_end] with size.
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If you exercise above your VO2 max, you create a larger [blank_start]oxygen deficit[blank_end].
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When [blank_start]lipids[blank_end] and carbohydrates are depleted, protein is used as fuel.
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In a non-starving individual exercising at a respiratory quotient (RQ) of 85, [blank_start]1/2[blank_end] of their energy is coming from lipids.
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Walking is [blank_start]more[blank_end] energy efficient than running.
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Aerobic scope is [blank_start]higher[blank_end] for animals who are better runners.
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Once your rate of energy usage exceeds VO2max, you switch to [blank_start]anaerobic respiration[blank_end] and start accumulating [blank_start]lactic acid[blank_end].
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anaerobic respiration
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lactic acid
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In the figure above, graph A represents [blank_start]cardiac output[blank_end], which is the same regardless of training; graph B represents [blank_start]heart rate[blank_end], which is lower in trained individuals; and graph C represents [blank_start]stroke volume[blank_end], which is lower in untrained individuals.
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cardiac output
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heart rate
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stroke volume
Frage 52
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The muscle labeled 'A' is the the [blank_start]external oblique[blank_end] muscle, which is an [blank_start]expiratory[blank_end] muscle.
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external oblique
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expiratory
Frage 53
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The black line, representing [blank_start]available ATP[blank_end] is the first fuel source used; the blue line, representing [blank_start]PCr (phosphocreatine)[blank_end] is the secondary fuel source; the purple line [blank_start]glycolysis[blank_end] is the tertiary fuel source. [blank_start]Oxydative phosphorylation[blank_end], represented by the red line, takes a time to start producing energy, but is more sustainable.
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The slope of this line is [blank_start]net cost of transport[blank_end].
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Graph [blank_start]B[blank_end] is likely to be more accurate because it controlled for more variables than did graph [blank_start]A[blank_end].
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[blank_start]Diffusion rate[blank_end], represented by the red line on the graph, doesn’t change as body mass changes.
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This graph is known as a [blank_start]Kleiber curve[blank_end].
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Hemoglobin oxygen affinity goes [blank_start]down[blank_end] when temperature is increased.
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In individuals who exercise regularly, total peripheral resistance [blank_start]decreases[blank_end] and the number of capillary beds around the lungs [blank_start]increases[blank_end].
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The unlabeled structures in the image to the left are [blank_start]Alveoli[blank_end].
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If you exercise close to your VO2 max, you’re burning primarily [blank_start]glycogen[blank_end].
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In a condition known as [blank_start]Pulmonary Edema[blank_end] diffusion of gases between alveoli and capillaries is impaired by some of the alveoli filling with fluid.
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[blank_start]Asthma[blank_end] is a disease treated with leukotriene inhibitors, inhaled glucocorticoids and bronchodilator drugs.
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In the image to the left: The blank is pointing to a collection of [blank_start]aortic bodies[blank_end]
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[blank_start]Anemic hypoxia[blank_end] occurs when arterial PO2 is normal but the total oxygen content of the blood is decreased because of inadequate numbers of erythrocytes, deficient or abnormal hemoglobin or competition for the hemoglobin molecule by carbon monoxide.
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A group of sensory receptors that are stimulated by strenuous exercise, pulmonary embolism or left ventricular heart failure are known as [blank_start]J receptors[blank_end].
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[blank_start]Squamous cell carcinoma[blank_end] makes up 20% to 40% of all lung cancer cases and arises in the bronchial epithelium.
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[blank_start]Obstructive Emphysema[blank_end] is distinguished by permanent enlargement of the alveoli and deterioration of the alveolar walls. This inflammation leads to damage of the pulmonary capillaries.
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The unlabeled structure in the image to the left is [blank_start]ventral respiratory group[blank_end].