Developmental Lecture 8 onwards

Beschreibung

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Zusammenfassung der Ressource

Frage 1

Frage
A morphogen:
Antworten
  • Is not expressed from a localised source in the embryo
  • Does not form a concentration gradient
  • Is not a signalling molecule
  • Specifies cell fates according to its concentration

Frage 2

Frage
Bicoid mRNA is tightly localised to the posterior end of the egg.
Antworten
  • True
  • False

Frage 3

Frage
Which of the following is not an example of induction?
Antworten
  • Xenopus animal cap assay
  • Homologous recombination
  • Anchor cell signalling to vulval precursors in the C.elegans embryo

Frage 4

Frage
In mosaic development, isolated cells are able to develop without external signalling.
Antworten
  • True
  • False

Frage 5

Frage
Somites give rise to which of the following...? (Multiple answers)
Antworten
  • Neural tube
  • Skeletal muscle
  • Notocord
  • Dermis
  • Glia

Frage 6

Frage
MyoD is sufficient to direct muscle development when transfected into non-muscle cells
Antworten
  • True
  • False

Frage 7

Frage
Reverse genetics uses the mutant phenotype as a starting point
Antworten
  • True
  • False

Frage 8

Frage
Which of the following are gain of function mutations...?
Antworten
  • Amorph
  • Antimorph
  • Neomorph
  • Hypomorph
  • Hypermorph

Frage 9

Frage
Kit and Steel are in the same gene
Antworten
  • True
  • False

Frage 10

Frage
Which of the following is the ligand-receptor pair Kit and Steel responsible for the normal development of...? (Multiple answers)
Antworten
  • Melanoblasts
  • Keratinocytes
  • Germ cells
  • Fibrocytes
  • Megakaryocytes
  • Haematopoietic stem cells

Frage 11

Frage
Which one of the following is the correct Hh pathway sequence?
Antworten
  • Hh ---| Ptc ---| Smo --> Ci ---> wg
  • Hh ---| Smo --> Ptc --> Ci ---| wg
  • wg ---> Ci ---> Ptc ---| Smo ---| Hh
  • wg ---| Smo ---| Ptc ---> Ci ---> Hh

Frage 12

Frage
Barchyury codes for a transcription factor responsible for the development of which germ layer?
Antworten
  • Mesoderm
  • Ectoderm
  • Endoderm
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