Cell Division and Basic Genetics

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Made for Rockhurst University course, General Biology I.
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cell division process by which cells make more cells; includes binary fission and the cell cycle (meiosis and mitosis)
binary fission cell division in bacteria and archaeons
gametes egg and sperm
prokaryotic cells a unicellular organism without a nucleus
eukaryotic cells a cell with a true nucleus
cell cycle describes the life of a eukaryotic cell; phases include: G1, S, G2, and M
M phase the parent cell divides; meiosis or mitosis
G1 phase "gap" phase; regulatory proteins are made and activated
S phase "synthesis" phase; DNA is replicated
G2 phase "gap" phase; cell makes lipids and enzymes
karyotype the organized portrait by number and shape of chromosomes representative of a species
haploid a cell with 1 set of chromosomes; n
diploid cells with 2 sets of chromosomes; 2n
sister chromatids two identical DNA copies attached at a centromere
mitosis autosomal cell division; "nuclear division"; starts with a diploid cell and ends with two diploid cells
cytokinesis cytoplasmic division
non-sister chromatids chromatids attached to different centromeres
crossover the physical breakage and reunion between nonsister chromatids; occurs in prophase I
meiosis division of sex cells into gametes; consists of two parts
allele different form of a gene
homologous chromosomes pair of duplicated chromosomes
Gregor Mendel father of genetics; discovered genes, not traits, are inherited
trait a characteristic
dominant the trait that always appears in the F1 generation if present A
recessive the contrasting trait from a dominant trait that only appears in the F1 generation if the dominant trait is not present a
genotype a combination of alleles
phenotype the physical expression of a genotype
principle of segregation (Mendel's Law of Segregation) the separation of alleles into different gametes
principle of independent assortment (Mendel's Law of Independent Assortment) the segregation of one set of alleles of a gene pair is independent of the segregation of another set of alleles of a different gene pair
pedigree diagram of ancestral relationships among individuals
autosomes chromosomes that are not sex chromosomes; 23 pairs of autosomes in humans
sex chromosomes X and Y chromosomes; the 24th pair of chromosomes in humans
nondisjunction chromosomes that fail to separate normally in meiosis
linked different alleles on the same chromosome
recombinants an offspring with a different combination of alleles from that of either parent resulting from one or more crossovers in prophase I
formula for total possible number of unique gametes 2^n where n = haploid number
Dominant Disease a disease that shows up in all generations and affects males and females equally; Huntington's; Aa or AA
Recessive Disease a disease that usually shows up in every other generation and affects males and females equally; cystic fibrosis, tay-sachs, sickle cell anemia; aa
Sex-Linked Recessive Disease (X-Linked Recessive Disease) diseases that affect each generation equally and predominates in males; color blindness, hemophilia; (X^n)(X^n), (X^n)(Y)
homozygous (pure-breed) AA or aa
heterozygous Aa
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