BMS03-1023 Pharmacology of Cholinergic Transmissions

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BMS03 - Nerve Signalling Karteikarten am BMS03-1023 Pharmacology of Cholinergic Transmissions, erstellt von Evian Chai am 22/04/2020.
Evian Chai
Karteikarten von Evian Chai, aktualisiert more than 1 year ago
Evian Chai
Erstellt von Evian Chai vor mehr als 4 Jahre
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Zusammenfassung der Ressource

Frage Antworten
How does Hemicholiniums block cholinergic transmission? Blocks the synthesis of ACh
How does AH5283 block cholinergic transmission? Prevents storage of ACh
Cholinergic neurotransmission uses what neurotransmitter? Acetylcholine
How does botox block cholinergic neurotransmission? Blocks exocytosis of ACh
What type of receptors are nicotinic receptors? Non selective cation channels
What are the two types of nicotinic drugs? 1. Skeletal muscle relaxants (antagonist) 2. Ganglion blockers (antagonist, lower BP)
Are skeletal muscle relaxants agonists or antagonists? Reversible or Irreversible? Competitive or Non-competitive? They are reversible competitive antagonists
What do muscarinic agonists do? Mimic the PNS
Which drug treats glaucoma by increasing aqueous humour flow? What kind of drug is this? Pilocarpine Muscarinic agonist
What drug is a stimulant laxative? What kind of drug is this? Bethanacol Muscarinic agonist
What do muscarinic antagonists do? What are their effects on the pupils? Inhibit the PNS Pupil dilation
What drug is used to treat sinus bradycardia? What type of drug is this? Atropine Muscarinic antagonist
Both muscarinic antagonists and B2 agonists can treat what? Asthma, as they block PNS/increase SNS effects eg. bronchodilation
What do Inhibitors of Acetylcholinesterase do? What does it do for the PNS? Prevent the breakdown of acetylcholine to increase neurotransmission Increases PNS activity eg. secretions, SM tone, hypotension, bradycardia
Which drug reverses skeletal muscle relaxants? What type of drug is this? Neostigmine AChE inhibitor
What inhibitor of AchE aids Alzheimers? Donepezil
What are the 5 main types of drugs impacting cholinergic transmission? 1. Skeletal muscle relaxants (cholinergic) 2. Ganglion blockers (cholinergic) 3. Muscarinic agonists 4. Muscarinic antagonists 5. Inhibitors of AchE
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