Molecules

Beschreibung

Pharmacy Karteikarten am Molecules, erstellt von Cyrielle Saba am 17/11/2020.
Cyrielle Saba
Karteikarten von Cyrielle Saba, aktualisiert more than 1 year ago
Cyrielle Saba
Erstellt von Cyrielle Saba vor etwa 4 Jahre
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Zusammenfassung der Ressource

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Nalbuphine K agonist mu antagonist
Naloxone antagonist orally inactive
naltrexone antagonist orally active
Dextromethorphan Mixed agonist/antagonist Lacks analgesia Antitussive activity
Meperidine Demerol 25% analgesic activity of morphine
Methadone RP=1 Orally active Longer DOA (19 hours) Maintenance therapy + pain suppression of terminally ill patients (cross tolerance)
Propoxyphene 10 times less potent than morphine Dextro-->analgesic Levo (-)-->antitussive
Loperamide Methadone and Meperidine hybrid Minimal analgesic activity Anti-diarrheal Orally active Very lipophilic but doesn’t enter CNS No central agonist action: Efflux protein P-gp actively Extensive first pass metabolism Low dissolution
Propantheline Amino alcohol ester
Trihexyphenidyl
Phenylephrine a1 agonist
Ephedrine a1, a2, b2 agonist
Name all mixed opioids Nalbuphine Pentazocine Cyclazocine Butorphanol Dezocine Dextromethorphan
Metaraminol a1 agonist
Tolazoline a blocker Pheochromocytoma
Practolol b1 blocker: effect on isoproterenol tachycardia but not hypotension visual loss
Propranolol b blocker 10x more potent than pronethalol
Demecarium AChEI
Ambenonium AChEI
Name all selective B1 blockers Acebutolol Atenolol Betaxolol Esmolol Metoprolol Bisoprolol NOT METIPRANOLOL
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