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Karteikarten von Adriana Vincelli-Joma, aktualisiert more than 1 year ago
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| Johann Gregor Mendel (1822 - 1884) | - Augustinian monk - 1856: studied plant heredity using pea plants - identified seven characteristics that bred true from generation to generation - demonstrated algebra of inheritance to explain transferral characteristics - law or segregation and law of independent assortment - disproved idea of blended inheritance - offered method for predicting how characteristics were distributed in populations over generations |
| New Synthesis | - combined Darwinism, Mendelism, and statistics of biometry to redefine continuous and discontinuous variation calculus-like terms - integration of geographical and species concerns with abstract mathematical population genetics |
| Friedrich Miescher (1844 - 1895) | - 1865: analyzed pus from discard hospital bandages to find cure for infections - discovered nuclein - nuclein was part of nucleus of cell and storage for phosphorous |
| Oswald T. Avery (1877 - 1955) | - worked with Colin Macleod and Maclyn McCarty - 1944, Rockefeller Institute in New York: demonstrated that genes and chromosomes were made of DNA |
| Colin MacLeod (1909 - 1972) | - worked with Oswald T. Avery and Maclyn McCarty - 1944, Rockefeller Institute in New York: demonstrated that genes and chromosomes were made of DNA |
| Alfred D. Hershey (1908 - 1997) | - worked with Martha Chase - 1952: discovered that phage viruses leave protein coasts behind and infect bacterial cells with DNA - showed DNA was genetic material - determined chemical composition of DNA |
| Martha Chase (1927 - 2003) | - worked with Alfred D. Hershey - 1952: discovered that phage viruses leave protein coasts behind and infect bacterial cells with DNA - showed DNA was genetic material - determined chemical composition of DNA |
| Maurice Wilkins (1916 - 2004) | - worked with Rosalind Franklin - used X-ray crystallography to analyze DNA - without Rosalind Franklin's permission, showed her photographs of DNA to Francis Crick and James Watson - 1962: Nobel Prize for Physiology or Medicine |
| Rosalind Franklin (1920 - 1958) | - worked with Maurice Wilkins - used X-ray crystallography to analyze DNA - 1951: produced X-ray diffraction photos of B form of DNA - photographs revealed double helix structure |
| Francis Crick (1916 - 2004) | - worked with James Watson to find structure of DNA - set out to build model that would agree with X-ray diffraction data, autocatalysis, and heterocatalysis - model was twisted ladder with two spines and base pairs arranged as rungs - April 2, 1953: published model in Nature - 1962: won Nobel Prize for Physiology or Medicine |
| James Watson (1928 - present) | - worked with Francis Crick to find structure of DNA - set out to build model that would agree with X-ray diffraction data, autocatalysis, and heterocatalysis - model was twisted ladder with two spines and base pairs arranged as rungs - April 2, 1953: published model in Nature - 1962: won Nobel Prize for Physiology or Medicine - 1968: wrote The Double Helix |
| The Double Helix (1968) | James Watson's controversial autobiographical account of the discovery of the double helix structure of DNA |
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