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Cell cycle | The life cycle of the cell, includes interphase, the four phases of mitosis, and cytokinesis. |
Interphase | The period of the cell cycle between cell division. Organelles replicate and DNA synthesis happens. |
Prophase | The first phase of mitosis. Chromosomes become visible (DNA coils up) and the centrioles separate to opposite sides of the cell (in animals). |
Metaphase | The second phase of mitosis, the chromosomes line up on the spindle, across the center of the cell. |
Anaphase | The third phase of mitosis, centromeres split, the spindle fibres shorten and chromosomes separate. |
Telophase | The the final stage of mitosis, a nuclear membrane forms around each set of new chromosomes. |
Cytokinesis | The final stage of the mitosis, in which the cell's cytoplasm divides into two new cells. |
Mitosis | Cell division in which the nucleus divides into two nuclei containing the same number of chromosomes. |
Mitotic index | The number of cells within a microscopic field that are undergoing mitosis; a high mitotic index is usually a more virulent malignancy. |
Mutagens | A chemical or physical agent that interacts with DNA and causes a mutation. |
Oncogenes | A gene whose activity is associated with the conversion of normal cells to cancer cells. |
Metastasis | The spread of cancer from its primary site to other places in the body. |
Prognostic tool | A method of predicting a future event, e.g. response of cancer cells to treatment. |
Primary tumor | The original site of a tumor, where the tumor originated. |
Cyclins | A group of proteins whose function is to regulate the progression of a cell through the cell cycle. |
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