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Frage | Antworten |
Name of cell-cycle specific drugs and their effect? | Antimetabolites Effective for high-growth-fraction malignancies |
Name of cell-cycle non-specific drugs and their effects? | Alkylating agents Effective for both low-growth-fraction malginancies (such as tumours) and high-growth-fraction malignancies |
What type of enzyme is telomerase? | A reverse transcriptase bound to RNA |
Whah function does RNA have for telomerase to work? | Acts as a template for extension of the 3' end of the parental strand |
What is myelosuppression? | Suppression of the bone marrow, resulting in decrease in white/red blood cells and platelet count |
What three -cytes are reduced as a result of myelosuppression? | Leukocytes (white) Erythrocytes (red) Thrombocytes (platelets) |
What is neutropenia? | A granulocyte disorder where there is an abnormally low number of neutrophils |
what is ALL? | Acute Lymphoblastic Leukaemia |
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