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Erstellt von Amelia Claire
vor mehr als 7 Jahre
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Frage | Antworten |
Unique characteristic of sympathetic nervous system is that: | It uses both noradrenaline and acetylcholine as neurotransmitters |
Acetylcholine is synthesised from: | Acetyl-CoA and choline |
Which cholinergic neurone will have voltage-gated calcium channels at the synapse? | Pre-synaptic neuron |
What is the main function of Acetylcholine esterase? | To degrade acetylcholine – end product is acetic acid and choline |
Why is atropine an antidote for nerve | It has anticholinergic effects |
What is the function of calcium in presynaptic nerve at the synapse? | To participate in neurotransmitter release from presynaptic nerves (acetylcholine) |
What happens in stage 3 at a cholinergic synapse? | Acetylcholine diffuses across the synaptic cleft and binds to receptors at the post synaptic nerve |
Which neurotransmitter is used at the neuromuscular junction? | Acetylcholine |
Indirect-acting cholinergic drugs are: | cholinergic drugs: Agonists of acetylcholine receptors (to PNS) |
Neostigmine is: | Reversible acetylcholine esterase inhibitor |
Which of these is NOT a cholinergic drug effect? 1. Sweating inhibition – drying effect 2. Lacrimation 3. Urinary incontinence 4. Diarrhoea | 1 - sweating. cholinergic drugs have a 'wetting' effect |
Pancuronium is: | Non-depolarizing neuromuscular blocker [competitive blocker] |
Parasympathomimetics are drugs that: | acts like acetylcholine; activates parasympathetic nervous transmission |
Opening of the eye pupil could be achieved by: | Parasympatholytics and Sympathomimetics |
Organophosphates are potent: | indirect acting parasympathomimetics |
Myasthenia gravis is caused by | Inactivation of nicotinic receptors |
Hyoscine is most similar to: Neostigmine Atropine Pancuronium (muscle relaxant -> anti cholinergic -> targets neuromuscular junction) | anticholinergic Atropine – targets muscularanic targets |
Overdose of neostigmine could be treated with: 1. Pilocarpine 2. Neostigmine 3. Atropine 4. Pancuronium | Atropine |
Major suxamethonium effect is: | Muscle relaxation |
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