Fundamentals Tutorial Week 5

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pharmacology (Tutorial Questions) Karteikarten am Fundamentals Tutorial Week 5, erstellt von Amelia Claire am 27/03/2017.
Amelia Claire
Karteikarten von Amelia Claire, aktualisiert more than 1 year ago
Amelia Claire
Erstellt von Amelia Claire vor mehr als 7 Jahre
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Zusammenfassung der Ressource

Frage Antworten
Unique characteristic of sympathetic nervous system is that: It uses both noradrenaline and acetylcholine as neurotransmitters
Acetylcholine is synthesised from: Acetyl-CoA and choline
Which cholinergic neurone will have voltage-gated calcium channels at the synapse? Pre-synaptic neuron
What is the main function of Acetylcholine esterase? To degrade acetylcholine – end product is acetic acid and choline
Why is atropine an antidote for nerve It has anticholinergic effects
What is the function of calcium in presynaptic nerve at the synapse? To participate in neurotransmitter release from presynaptic nerves (acetylcholine)
What happens in stage 3 at a cholinergic synapse? Acetylcholine diffuses across the synaptic cleft and binds to receptors at the post synaptic nerve
Which neurotransmitter is used at the neuromuscular junction? Acetylcholine
Indirect-acting cholinergic drugs are: cholinergic drugs: Agonists of acetylcholine receptors (to PNS)
Neostigmine is: Reversible acetylcholine esterase inhibitor
Which of these is NOT a cholinergic drug effect? 1. Sweating inhibition – drying effect 2. Lacrimation 3. Urinary incontinence 4. Diarrhoea 1 - sweating. cholinergic drugs have a 'wetting' effect
Pancuronium is: Non-depolarizing neuromuscular blocker [competitive blocker]
Parasympathomimetics are drugs that: acts like acetylcholine; activates parasympathetic nervous transmission
Opening of the eye pupil could be achieved by: Parasympatholytics and Sympathomimetics
Organophosphates are potent: indirect acting parasympathomimetics
Myasthenia gravis is caused by Inactivation of nicotinic receptors
Hyoscine is most similar to: Neostigmine Atropine Pancuronium (muscle relaxant -> anti cholinergic -> targets neuromuscular junction) anticholinergic Atropine – targets muscularanic targets
Overdose of neostigmine could be treated with: 1. Pilocarpine 2. Neostigmine 3. Atropine 4. Pancuronium Atropine
Major suxamethonium effect is: Muscle relaxation
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