Which one of the following is NOT true about Kell system antibodies
Usually clinically significant IgG antibodies
Best detected in indirect antiglobulin tests
Fail to react in enzyme tests
Do not activate complement
Antibodies to the Kell, Kidd and Duffy systems all share the following traits except
Can cause haemolytic disease of the newborn and foetus
Enhanced with enzyme treatment
Can cause haemolytic transfusion reactions
usually detected only by indirect antiglobulin test
Which of the following phenotypes is heterozygous
Fy(a-b+)
Jk(a+b+)
Lu(a-b-)HIV
Jk(a-b+)
Which of the antibodies from the following blood group systems shows a dosage effect?
Lutheran
Kell
Duffy
P
Lewis
Antibodies to k antigen are not commonly detected in transfusion screening because
k antigen is of high incidence
the antibodies do not cause transfusion reactions
antibodies best react at 4 degree (C)
The antigen is of low incidence
k antigen is not present on screening cells
Lewis system antibodies have not been implicated in haemolytic disease of the new born and foetus because
the antigens are not fully developed at birth
Lewis system antibodies do not cross the placenta
the antibodies are not clinically significant
the antigens are primarily plasma based
All of the above
The Donath-Landsteiner antibody is
an IgG auto anti-P
an IgM auto anti-P
an IgM auto anti-I
anti-IH that reacts at cold temperatures
Which of the following cells has the highest concentration of M antigens
MNSs
MNs
NSs
MSs
NS
Which of the following does not result in an Lu(a-b-) phenotype
Deletion of the genes on the Lu locus
Amorphic genes of the Lu locus
Delayed anamestic heamolytic transfusion reaction
A suppressor gene on the X-chromosome
An inhibitor gene on another locus
The top and bottom pack comprises of
Single packs joined together
Triple pack
Double pack
Quadruple pack
