Biology 4.1.1 Antigen presentation

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A level Biology (4.1.1 Diseases) Flashcards on Biology 4.1.1 Antigen presentation, created by Sam Gunnell on 05/06/2019.
Sam Gunnell
Flashcards by Sam Gunnell, updated more than 1 year ago
Sam Gunnell
Created by Sam Gunnell over 5 years ago
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Resource summary

Question Answer
What type of phagocyte turn into antigen presenting cells? Macrophages
What is the name of the process in which a macrophage engulfs a microbe? Phagocytosis
What happens before the pathogen is engulfed? The antigen on the pathogen attaches to receptors on the macrophage
What happens when a macrophage engulfs a pathogen? 1) It is enclosed in a vesicle (phagosome) 2) The lysosomes fuse with the phagosome forming a phagolysome 3) The pathogen is digested by hydrolytic enzymes within the lysosome 4) Fragments of the antigen is presented on the surface of the macrophage and waste products are removed
By what procewss does waste products leave the macrophage? Exocytosis
What key word is used to describe an enzyme breaking down a pathogen? Digests
How do neutrophils deal with pathogens? Similarly to macrophages, the antigens of the pathogen bind to receptors and is englufed by endocytosis forming a phagosome. Lysosomes fuse with the phagosome and release lytic enzymes into it. The pathogen is completly destroyed and the neutrophil dies
Give a difference between how macrophages and neutrophils deal with pathogens ~Macrophages don't fully destroy the pathogen so it can be presented and the macrophage stays alive after ~Neutrophils fully destroy the pathogen and die after
What are the two things that happen once a pathogen is found? ~It is englufed by macrophages, releases cytokines to activate T lymphocytes, producing T killer and T helper cells (the T helper cells can turn into memory (T cells) ~Complimentary B lymphocytes engluf patjhogen and divide to form many memory B cells and plasma cells that produce antibodies
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