6684987
Description
Flashcards by Austin Thomas, updated more than 1 year ago
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Created by Austin Thomas
about 8 years ago
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| Question | Answer |
| What is pharmaceutics? | Science of dosage form design |
| Drug? | Active chemical of drugs |
| Dosage form? | Formulation Drug with inert ingredients |
| Examples of Liquids? | Solutions, emulsions, suspensions |
| Examples of Solids? | Ointments, creams, pastes, gels |
| Examples of Semi-Solids? | Powders, granules, capsules, tablets |
| Drug Delivery System? | Drug in dosage form intended for a particular purpose or Route of Administration |
| What are the different Routes of Administration? | |
| What is bioavailability? | Unit-less value, often in percent "Fraction of admin dose that reaches physiological activity usually determines onset and extent, AUC determines duration of Action |
| What are colligative properties? | Dependent on total number of species in solution, (solute + solvent) Examples; Boil Point, Freezing Point, Water Vapor, etc.. |
| What happens to blood cells when exposed to the following; hypotonic, isotonic, hypertonic solutions? | Hypotonic? solute concentration lowers outside, cells will swell and burst Isotonic? solute concentration is equal Hypertonic? solute concentration is higher inside, cells shrink and shrivel |
| Determine the number of species a drug molecule will dissociate into; "glucose" | Non-Electrolyte **There is only one species here due to only being a solute present in product, also there is not another component to the chemical** |
| Determine the number of species a drug molecule will dissociate into; "Dextrose" | Non-Electrolyte **There is only one species here due to only being a solute present in product, also there is not another component to the chemical** |
| Determine the number of species a drug molecule will dissociate into; "Urea" | Non-Electrolyte **There is only one species here due to only being a solute present in product, also there is not another component to the chemical** |
| Determine the number of species a drug molecule will dissociate into; "Ranitidine HCl" | Weak-Base **There are 3 species here, one is the entire chemical, and then one from the Active Drug itself and then one from the salt** |
| Determine the number of species a drug molecule will dissociate into; "Homatropine HBr" | Weak-Base **There are 3 species here, one is the entire chemical, and then one from the Active Drug itself and then one from the salt** |
| What is the relationship between MW and molecular size? | MW = Total weight of molecule when you add up each component Molecular Size = Size of the molecules Direct Relationship between 2 values |
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