Past Papers

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Past Papers Flashcards on Past Papers, created by laura.marsland on 15/05/2013.
laura.marsland
Flashcards by laura.marsland, updated more than 1 year ago
laura.marsland
Created by laura.marsland over 11 years ago
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List 3 reasons why blood is considered a connective tissue 1. It is mesoderm-derived 2. It contains fibres (which are soluble in clotted blood) 3. It has a fluid/semi-fluid matrix
Give three possible molecular explanations for the presence of abnormal haemoglobins in a patient’s blood 1. Production of structurally abnormal haemoglobin molecules due to mutation in globin structural gene 2. Presence of abnormal ratio of subunits due to over or under production of globin subunits 3. Change in post-translational modification of globin sub-units
Explain why a patient with anaemia is likely to feel tired Low haemoglobin is associated with a reduced ability to carry oxygen tissues. Lack of oxygen in tissues reduces aerobic metabolism. Reduced aerobic metabolism means inadequate ATP level to maintain cell function.
What happens to carbohydrate eaten in excess of the body's requirement? Stored as glycogen in the liver and skeletal muscle Converted to fatty acids and stored as triacylglycerols in adipose tissue
Give 4 histological features of adipocytes in white adipose tissue Large lipid droplet (triacylglycerols) filling cell Nucleus pushed to one side Small amount of cytoplasm pushed to one side Small number of mitochondria
How are fatty acids transported in the blood? They are hydrophobic and can only be transported bound to albumin
Why does the concentration of fatty acids never exceed 3mM? Saturation of binding sites on albumin
Define axonotmesis Axon is ruptured but myelin sheath remains in tact
Define neurotmesis Complete severance of axon & myelin sheath of peripheral nerve
Define neuropraxia 'Nerve shock'. Axon & myelin remain in tact but conduction temporarily disrupted
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