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101552
Blood Physiology
Description
bacalaureat Physiology Mind Map on Blood Physiology, created by Caroline Oxford on 21/05/2013.
No tags specified
physiology
physiology
bacalaureat
Mind Map by
Caroline Oxford
, updated more than 1 year ago
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Created by
Caroline Oxford
over 11 years ago
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Resource summary
Blood Physiology
Blood Values
Haematocrit (packed RBC)= 45%
Volume About 5l
Plasma K+ 4.5 mmol/l-1
Plasma Na+ 140 mmol/l-1
Random Glucose 5 mmol/l-1 Fasting 4.4-6.1
Platelet count 300,000/mm3
pH 7.35-7-45
Plasma volume 40ml kg-1 body weight
Haemoglobin count 12-14 W, 14-16g/dl-1 in men
RBC count 4-6x10 to the 12L-1
Plasma 55%
Albumin
A protein made in liver
highest concentration, contributes to colloid osmotic pressure
Globulins
specific transport proteins
eg. Transferrin for iron
Clotting factors
Inactive precursors of certain hormones
eg. Angiotensinogen
Immunoglobulins, act as circulating antibodies
Fibrinogen
converted to Fibrin during clotting
Serum=Plasma without Fibrinogen (Platelets)
Erythrocytes
Develop in liver, spleen + lymph nodes before birth
Develop in the marrow of long bones, then ribs, pelvis etc as we get older
formed from Erythroid cell (committed stem cell)
120 day life span
Erythropoiesis
controled by Kidneys- Produces Erythroprotein
Reads O2 levels, not haemoglobin level
High altitudes increases Erythropoiesis
Needs VitB12 & Folic acid
From Diet
Parietal cells in stomach, secrete intrinsic factor which binds to B12
Lack of Intrinsic factor, results in less VitB12. Pt often jaundice from Bilirubin (from breakdown of RBC)
Needs Iron for Haemoglobin
Blood Groups
0 Group
No Antigens on cell
Anti-A & Anti-B in plasma
Universal Donor
Must receive O
A Group
A Antigens
Anti-B
Must recieve A
All 3 can recieve O
B Group
B Antigens
Anti-A
Must recieve B
AB Group
A&B Antigens
No Antibodies
Universal recipient
All IgM antibodies
WBC + Platelets
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