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103147
Renal Regulation of ECF Volume
Description
The Kidneys Mind Map on Renal Regulation of ECF Volume, created by jessica.neilan on 22/05/2013.
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the kidneys
the kidneys
Mind Map by
jessica.neilan
, updated more than 1 year ago
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jessica.neilan
over 11 years ago
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Resource summary
Renal Regulation of ECF Volume
Natriuresius: with positive Na balance there is an increase in ECF volume which causes an increase in Na excretion
Effective Circulating Volume: the portion of the ECF that is contained within the vascular system and is effectively perfusing tissue
Varies directly with ECF volume, blood pressure and cardiac output
Volume Sensing Systems
CARDIOVASCULAR
Baroreceptors
Stretch receptors
Pressure receptors
5% change in pressure is required to evoke a response
Alters (decreases) sympthetic activity and ADH secretion
afferent arteriole constricted by alpha adrenergic receptor
Decreases hydrostatic pressure within glomerular capillary lumen
Decrease in GFR
Filtered Na is reduced
Renin secreted
increased SNS activity drceases excretion of Na to restore ECF
JUXTAGLOMERULAR APPARATUS: decrease in pressure causes secretion of renin
Atrial myocytes release peptide hormone ATRIAL NATRIURETIC PEPTIDE ANP during volume expansion
Antagonises renin-AII-aldosterone system
Afferent dilation to increase GFR so more Na is filtered
Inhibits renin secretion to reduce aldosterone release
reduces ADH release
Inhibits Na reabsorbtion in collecting duct
Raises cGMP levels
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