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22273965
CLOSTRIDIUM DIFFICILE
Description
Mind Map on CLOSTRIDIUM DIFFICILE, created by Sandra Jiménez on 24/04/2020.
Mind Map by
Sandra Jiménez
, updated more than 1 year ago
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Created by
Sandra Jiménez
over 4 years ago
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Resource summary
CLOSTRIDIUM DIFFICILE
Bacilo Gram-positivo anaerobio esporulado
Mircroflora natural del intestino
Sintetiza 2 tóxinas
Enterotoxina (toxina A)
Quimiotáctica para neutrófilos
liberación de citocinas
Efecto citopático
Incremento permeabilidad pared intestinal
DIARREA
Citotoxina (toxina B)
Provoca despolimerización actina
Destrucción del citoesqueleto celular
EXPOSICIÓN PROLONGADA A ANTIBIOTICOS
Crecimiento excesivo C.Difficile
PX inmunocomprometido
CLINICA
Diarrea acuosa leve-moderada
Colitis sin formación de pseudomembranas
Fiebre, diarrea acuosa con o sin sangre, nauseas, dolor abdominal,leucocitosis,
Colitis pseudomembranosa
Dolor abdominal, diarrea con sangre, fiebre, hipoalbuminemia
+ GRAVE
DIAGNOSTICO
Cliníca
Cultivo
Endoscopia
TAC
TRATAMIENTO
Suspender Antibioticos implicados
Metronidazol o Vancomicina
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