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309797
Competitive and Noncompetitive Inhibitors
Description
Topic 3 - Metabolism Mind Map on Competitive and Noncompetitive Inhibitors, created by kathrynmoar on 28/10/2013.
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topic 3 - metabolism
topic 3 - metabolism
Mind Map by
kathrynmoar
, updated more than 1 year ago
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Created by
kathrynmoar
almost 11 years ago
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Resource summary
Competitive and Noncompetitive Inhibitors
Competitive Inhibitors
mimic the substrate and compete for the binding to the active site
effectiveness = depends on affinities for that site.
Km is increased in a double reciprocal plot
Noncompetitive Inhibitors
bind at a site other than the active one which means no competition with the substrate
Example: covalent modififcation - the action of aspirin in acylating cyclooxygenase at a serine at the active site
Uncompetitive inhibition
inhibitor binds to the ES complex only
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