The Cytoskeleton

Description

Degree Pharmacy (PH1402 - Cell and Molecular Biology) Mind Map on The Cytoskeleton, created by Has Maj on 02/12/2015.
Has Maj
Mind Map by Has Maj, updated more than 1 year ago
Has Maj
Created by Has Maj almost 9 years ago
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Resource summary

The Cytoskeleton
  1. PROTEIN FIBRES
    1. Micro/Actin filaments
      1. Made of F and G actin subunits
        1. Smallest of the protein fibres
          1. Involved in cell movement
            1. Each actin molecule has a Mg ion binding site
              1. Requires lots of ATP to make ADP +Pi formed
              2. Micotubules
                1. Made from Alpha and Beta Tubulin fibres
                  1. Largest of the protein fibres
                    1. They involved in intracellular transport, cell division
                      1. Motorway system to all areas of the cell
                      2. Intermediate Filament
                        1. Middle Size
                          1. Made of tetramers formed of proteins
                            1. Mechanical strength and structural support
                              1. Rope like, across the whole cell
                                1. Involved in cell-cell interaction
                                2. WHAT IS IT MADE OUT OF?
                                3. WHAT ROLE DOES IT HAVE?
                                  1. Gives the cell a mobile shape
                                    1. Allows the cell to move
                                      1. Intercellular transport
                                        1. Responsive to inter and extra celluar signals
                                        2. WHAT IS IT?
                                          1. A framework of proteins made up of three subunits
                                            1. Made from subunit proteins which form polymers
                                            2. POLYMERISATION
                                              1. Nucleation (lag phase)
                                                1. Small sunits may form together to form oligomer
                                                2. Elongation (growth phase)
                                                  1. Subunits only add on one side of the molecule (+) end
                                                  2. Steady State (equilibrium phase)
                                                    1. Where the rate of subunit addition and loss are equal
                                                      1. Called the critical condition =Cc
                                                      2. Accessory proteins increases the speed of the process
                                                      3. Requires lots of ATP
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