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468699
Malabsorption
Description
Paediatrics (Gastroenterology & nutrition) Mind Map on Malabsorption, created by v.djabatey on 07/01/2014.
No tags specified
gastroenterology & nutrition
paediatrics
paediatrics
gastroenterology & nutrition
Mind Map by
v.djabatey
, updated more than 1 year ago
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Created by
v.djabatey
over 10 years ago
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Resource summary
Malabsorption
manifestations of disorders affecting digestion or absorption of nutrients
abnormal stools
true malabsorption stool
hard to flush down the toilet
odour pervades whole house
colour is poor guide to abnormality
failure to thrive or poor growth
seen in most but not all cases
inapprop to ix kids for malabsorption as a cause of failure to thrive when dietary intake is low & other sx absent
specific nutrient deficiencies
reliable dietary assessment is important
can be pan-malabsorption
poor absorption of many nutrients
can be highly specific
e.g. Zn malabsorption
acrodermatitis enteropathica
causes of nutrient malabsorption
cholestatic liver disease or biliary atresia
bile salts no longer enter duodenum in bile
-> defective solubilisation of products of triglyceride hydrolysis
-> fat and fat-soluble malabsorption
exocrine pancreatic dysfunction
e.g cystic fibrosis
absent lipase, proteases & amylase
-> defective triglyceride, protein and starch digestion (pan-malabsorption)
small intestinal mucosal disease
loss of absorptive surface area
e.g. coeliac disease
specific enzyme defects
e.g. lactase deficiency ff gastroenteritis
common in Black & Oriental races
specific transport defects
e.g. glucose-galactose malabsorption
severe life-threatening diarrhoea with 1st milk feed
acrodermatitis enteropathica
zinc malabsorption
erythematous rash of mouth & anus
lymphatic leakage or obstruction
chylomicrons (containing absorbed lipid) unable to reach thoracic duct & sys circulation
e.g. intestinal lymphangiectasia (abnormal lymphatics)
short bowel syndrome
small intestinal resection
due to congenital abnormalities or necrotising enterocolitis
-> nutrient, water & electrolyte malabsorption
loss of terminal ileal function
e.g. resection or Crohn disease
absent bile acid and absent B12 absorption
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