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Streptococcus Pyogenes

Characteristic
1. most serious
2. inhibits throat, nasopharynx, occasionally skin
3. catalase -
Virulence fc
1. Produce surface antigens
  1. C-carbohydrate
  2. fimbriae
  3. M-protein
  4. hyaluronic acid capsule
  5. C5a protease hinders com.
  6. neutrophile response
2. Extracellular toxins
  1. streptolysin
  2. pyrogenic
  3. superantigen
3. Extracellular enzymes
  1. streptokinase
  2. hyaluronidase
  3. DNase
Epidemiology & Pathogenesis
1. human reservior
2. children predominant-cutaneous & throat infec.
3. trans-ctc, droplets, fd, fomites
4. entry-skin / pharynx
Diseases
1. skin infec.
  1. impetigo
  2. erysipelas
2. throat infec.
  1. S. pharyngitis
3. systemic infec.
  1. scarlet fever
  2. septicemia
  3. pneumonia
  4. S. TSS
4. long term effect
  1. rheumatic fever
  2. acute glomerulonephritis

Streptococcus Pyogenes

	Created by adam94 almost 11 years ago