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Th2L02 DNA replication
Description
Medicine Y1 (Theme 2 | Genetics) Mind Map on Th2L02 DNA replication, created by Emma Allde on 20/08/2016.
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medicine y1
theme 2 | genetics
Mind Map by
Emma Allde
, updated more than 1 year ago
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Created by
Emma Allde
about 8 years ago
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Resource summary
Th2L02 DNA replication
Part of the cell cycle
G1 phase
Synthesis of protein components necessary to complete the cell cycle including histones, enzymes for replication, etc.
Takes 6-9 hours
S phase:
DNA synthesis commences
Overview
(1) DNA unwinds
(2) Daughter strands of DNA produced from parent strand at replication for
Semi conservation replication (each new DNA molecule contains one parent and one daughter strand)
Overall structure of the replication fork
Replication occurs 3' to 5' along parent strand
Leading strand
The new continuous complementary DNA strand synthesised along the template strand in the mandatory 5' to 3' direction.
Lagging strand
A discontinuously synthesised DNA strand that elongates by means of Okazaki fragment
Okazaki fragments
Small fragments of DNA produced on the lagging strand during DNA replication
Joined later by DNA ligase to form a complete strand
Each synthesised in a 5' to 3' direction away from the replication fork.
New daughter strand is formed 5' to 3'
One leading strand and one lagging strand
Several enzymes are involved including helicase, DNA polymerase, primase, DNA ligase, etc.
Takes 8-9 hours
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