Topic 1: Scientific Inquiry, Cells and Exchange of Materials

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Scientific Inquiry, Cells and Exchange of materials
Kaysey Johnstone
Mind Map by Kaysey Johnstone, updated more than 1 year ago
Kaysey Johnstone
Created by Kaysey Johnstone about 8 years ago
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Topic 1: Scientific Inquiry, Cells and Exchange of Materials
  1. Human Cells
    1. cells are the basic structural and functional units of living organisms.
      1. Cell Structure
        1. Cell/plasma membrane - outer cell boundary.
          1. Cytoplasm
            1. Cytosol - liquid part of the cytoplasm
              1. Cytoskeleton - fibrous protein scaffolding in the cytoplasm.
                1. Inclusions - granules or drops of liquid chemicals found in the cytoplasm.
                  1. Organelles - structures with different functions suspended in the cytoplasm.
                    1. Centrioles
                      1. a pair of cylindrical structures located near the nucleus. They are involved in the reproduction of the cell.
                      2. Nucleolus
                        1. it is composed of mainly RNA. It is inside the nucleus.
                        2. Endoplasmic Reticulum
                          1. parallel membranes provide a surface for chemical reactions to happen while the channels are for storing or transporting molecules.
                          2. Nucleus
                            1. spherical shape that contains the genetic material (DNA). It is the largest organelle in the cell. A nuclear membrane separates the nucleus from the cytoplasm. The membrane has nuclear pores that allow for larger molecules to pass through.
                            2. Golgi Apparatus
                              1. it is a series of flattened membranes stacked near the nucleus. It modifies proteins and packages them for secretion from the cell. Vesicles form on the edges and package the proteins that are produced at the ribosomes and passed through the ER.
                              2. Lysosomes
                                1. small spheres that contain enzymes able to break down proteins, lipids, nucleic acids and some carbohydrates. They break down materials brought into the cell or worn out organelles.
                                2. Cell membrane
                                  1. the outer boundary that separates the cell contents from neighbouring cells and from the external environment. Made up of a double layer of lipid molecules and associated proteins.
                                  2. Nuclear pores
                                    1. allow for larger molecule to pass through into the nucleus.
                                    2. Mitochondria
                                      1. each has a double membrane. Smooth outer layer surrounds the mitochondria and the inner layer forms a series of folds. The folds create a larger surface area where chemical reactions can happen, like cellular respiration.
                                      2. Ribosomes
                                        1. here amino acids are joined together to make proteins. They can be free in the cytoplasm or attached to membranes within the cell.
                                        2. Nuclear membrane
                                          1. separates the nucleus from the cytoplasm. It acts as a double membrane, two membranes separated by space.
                                    3. Surface Area to Volume Ratio
                                      1. = Surface Area / Volume
                                        1. As length of the sides increase, the SA/V ratio decreases.
                                          1. It means cells become less efficient in exchanging nutrients and wastes within its environment.
                                      2. Cells Exchange Materials
                                        1. Homeostasis - the working together of body systems to keep the cell environment constant.
                                          1. All cells need oxygen and glucose for cell respiration.
                                            1. respiration produces carbon dioxide and water as wastes.
                                            2. Cell membrane functions:
                                              1. physical barrier - cytoplasm and tissue fluids have different compositions.
                                                1. it regulates passage of materials between cells and surrounding tissue fluid.
                                                2. Support - internal parts of the membrane are attached to cytoskeleton for support. Connections between neighbouring cells support the whole tissue.
                                                  1. Sensitivity - receptors are sensitive to particular molecules.
                                                  2. Cell membrane structure:
                                                    1. Bilayer - single membrane made of 2 layers
                                                      1. Made mostly of phospholipids and proteins scattered through.
                                                      2. Differentially permeable membrane allows certain ions & molecules to pass through but restrict others.
                                                        1. Fluid mosaic model, phospholipid bilayer
                                                          1. Hydrophilic - water loving - outside
                                                            1. Hydrophobic - water hating - inside
                                                              1. Cholesterol and Proteins
                                                                1. they are embedded in the bilayer.
                                                                  1. cholesterol is found between the phospholipids.
                                                                    1. maintains the integrity of the membrane and helps communication with other cells.
                                                                    2. Proteins - channel, receptor, carrier and cell-indentity markers.
                                                                      1. some proteins are found on the surface while others go right through.
                                                                2. Experimentation
                                                                  1. Independent variable - the one we change
                                                                    1. Dependent variable - the one measured
                                                                      1. validity - should control all variables so that all factors known to affect the results are kept the same for experimental purposes.
                                                                        1. Accuracy - it is how close the measured results are to the actual results.
                                                                          1. Reliability - it is the extent to which an experiment gives us the same results each time is performed.
                                                                          2. Transport across the cell membrane
                                                                            1. Diffusion - passive process from the random movement of ions and molecules.
                                                                              1. Osmosis - water diffusion across the membrane.
                                                                                1. The concentration of water decreases as amount of dissolved solute increases.
                                                                                  1. Water moves across the membrane from high water concentration to low water concentration until its concentration is equal on both sides.
                                                                                    1. Osmosis causes swelling and increase of mass in direction of water movement; reverse in opposite direction.
                                                                                    2. The molecules move from high concentration to low concentration until concentration is equal.
                                                                                      1. Net diffusion is the overall direction the molecules move.
                                                                                        1. Fat-soluble substances, alcohol, oxygen and carbon dioxide diffuse through the phospholipid bilayer.
                                                                                          1. Water soluble substances diffuse through protein channels in the membrane. The channels have a small diameter so that small molecules pass through but larger molecules are restricted.
                                                                                            1. The concentration gradient (diffusion gradient) is the difference in concentration between the 2 sides of the membrane that causes diffusion.
                                                                                              1. The greater the difference in concentration, the steeper the diffusion gradient and the faster diffusion occurs.
                                                                                            2. Carrier-mediated transport - can be passive or active process, it requires special proteins.
                                                                                              1. Facilitated diffusion
                                                                                                1. the molecules are too big to fit through the pores so they are moved through by carrier proteins.
                                                                                                  1. Transported molecules bind to a carrier protein. The carrier protein changes shape, moving transported molecule to other side of membrane.
                                                                                                    1. Passive process - do not require energy
                                                                                                    2. Active transport (ATP is cell energy)
                                                                                                      1. Active process - require metabolic energy (cellular energy required ATP)
                                                                                                        1. the molecules are pumped across the membrane against the concentration gradient - from low to high.
                                                                                                      2. Vesicular transport - an active process where materials are moved in membrane-bound sacs.
                                                                                                        1. molecules move in and out of the cell in vesicles.
                                                                                                          1. vesicles are bubble-like structure surrounded by a membrane.
                                                                                                            1. the membrane of the vesicle can form at the cell membrane - endocytosis (importation)
                                                                                                              1. the cell membrane surrounds the fluid/molecules and results in the material enclosed inside the membrane.
                                                                                                                1. Phagocytosis - endocytosis of solid particles - specialised cells engulf and break down solid molecules.
                                                                                                                  1. Pinocytosis - endocytosis of liquid particles which is a function of all cells.
                                                                                                                  2. the membrane can fuse with the cell membrane - exocytosis (exportation)
                                                                                                                    1. the contents of a vesicle are pushed through the cell membrane.
                                                                                                                      1. it can be waste or excretion - saliva
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