Lymphatic System and Immunity

1. Lymphatic Capillaries
2. Lymphatic Vessels
3. Lymph Nodes
4. Lymphatic Trunks
5. Lymphatic Ducts
6. Primary Lymph Organs
   1. Thymus - T-Cells are formed

      Annotations:

      • what is inveloom?
      • The thymus is where t and b cells mature
      1. Hangs over heart, largest at puberty, shrinks as we age, makes t-cells, immunocompitent
   2. Red Bone Marrow - B- cells
7. Secondary Lymph Organs and Tissues
   1. Spleen

      Annotations:

      • holds platelets- w/o spleen clotting can become problematic
      1. White and red pulp; platelets are stored here; white-lymphatic tissue; old rbc's are destroyed here
   2. Lymph Nodes
      1. Scattered along lymphatic vessels; superficial and deep; serve as filters

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• lymph fluid moves by respitory pump

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• There are more Afferent vessels then efferent, this is to give the B and T cells a chance to attack.

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• Less of these, and they leave the lymph node through the hilum (indentation)

1. Innate

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   • We are born with this type of immunity, we get this from Mom
   • At birth we have non-specific and non adaptive immunity (immune response), this includes 1st and 2nd line of defense pgs 886-888 in text
2. Adaptive (aquired)

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   • two types, cell mediated or antibody mediated, both are gained through vaccines
   • Describes the ability of the body to adapt defenses against antigens of specific bacteria, viruses, foreign tissue.....even toxins
   1. Cell mediated
   2. Antibody Mediated

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• the sides of the lymphatic system

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• Specialized lymphatic capillaries

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• wandering macrophages

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• "Terminator" cells - goes after cancer cells without hesitation - the theory is that we are born with only so many

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• The beta ones are used to treat and to slow the progress of MS

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• There are 5 steps: Chemotaxis, Adherence, Ingestion, Digestion, Killing