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Pesticide Poisoning Caused Toddler’s
Death
- the Nervous System
- CNS
- PNS
- Somatic nervous
system (skeletal
muscle)
- Autonomic nervous
system (cardiac and
smooth muscle
- Sympathetic
(fight or flight)
- parasympathetic
(resting)
- Sympathetic
(fight or flight)
- Somatic nervous
system (skeletal
muscle)
- requires neurons synapse
- forming synaptic cleft
- works by neurotransmitters
- both
- Acetylcholine
- Nor epinephrine
- Small-molecule, rapid acting
transmitter. Synthesized in
pre-synaptic terminal. Mostly
excitatory except in heart.
- Nor epinephrine
- Acetylcholine
- inhibitory
- Glycine
- GABA
- Serotonin
- Dopamine
- Dopamine
- Serotonin
- GABA
- Glycine
- excitatory
- Glutamate
- Aspartate
- Nitric oxide
- Nitric oxide
- Aspartate
- Glutamate
- both
- works by neurotransmitters
- forming synaptic cleft
- CNS
- Food poisoning
- Symptoms
- Nausea
- Vomiting
- Watery
diarrhea
- Abdominal
pain and
cramps
- Fever
(rare)
- Nausea
- Common Causers
- Clostridium botulinum
- Clostridium perfringens
- E. Coli
- Noroviruses
- Salmonella & Shigella
- Staph aureus
- Bacillus cereus
- Bacillus cereus
- Staph aureus
- Salmonella & Shigella
- Noroviruses
- E. Coli
- Clostridium perfringens
- Clostridium botulinum
- Risk Factor
- Pregnant women
- Elderly weaker immune system
- Infants and young
children immune
systems not fully
developed
- People with weakened immune
system e.g AIDS & chemotherapy
and radiotherapy & NSAIDS and
SAIDS
- People with weakened immune
system e.g AIDS & chemotherapy
and radiotherapy & NSAIDS and
SAIDS
- Infants and young
children immune
systems not fully
developed
- Elderly weaker immune system
- Pregnant women
- Complications
- Severe dehydration
can be fatal
- Severe dehydration
can be fatal
- Symptoms
- The most
common
household
poisons
- Medicines - Carbon monoxide -
Button batteries - Iron pills -
Cleaning products - Nail glue
remover and nail primer -
Hydrocarbons- Pesticides -
Windshield washer solution and
antifreeze - Wild mushrooms -
Alcohol - Drain cleaners and
toilet bowl cleaners - Topical
anesthetics
- Medicines - Carbon monoxide -
Button batteries - Iron pills -
Cleaning products - Nail glue
remover and nail primer -
Hydrocarbons- Pesticides -
Windshield washer solution and
antifreeze - Wild mushrooms -
Alcohol - Drain cleaners and
toilet bowl cleaners - Topical
anesthetics
- Organophosphate Poisoning
- Organophosphate uses
- Insecticides - Herbicides
Nerve gas -
Anthelmintic drugs -
Ophthalmic agents
- Insecticides - Herbicides
Nerve gas -
Anthelmintic drugs -
Ophthalmic agents
- Pathophysiology
- Effects
- Organophosphate uses
- Emergency management
- History taken
- Clinical evaluation
- Toxicology
laboratory
- ABC approach
- general care
- Resuscitiation
- History taken
- Lab investigations
- Cholinesterase Tests
- RFT
- LFT
- Cholinesterase Tests
- Autopsy
- Types
- forensic
- Clinical autopsy
- Academic autopsy
- virtual autopsy
- forensic
- postmortum examination
performed to confirm the
cause of death
- Types
- Long-Term Health Effects of Chemical Poisoning
- Damage to the lungs - Cancer -
Damage to the liver- Toxic hepatitis -
Damage to the nervous system-
Damage to the immune system -
Sterility - Birth defects - Damage to
hormone-producing glands
- Damage to the lungs - Cancer -
Damage to the liver- Toxic hepatitis -
Damage to the nervous system-
Damage to the immune system -
Sterility - Birth defects - Damage to
hormone-producing glands
- Hemodynamic Monitoring
- The assessment of the
Cardiovascular System - Arterial
Blood Pressure - Central Venous
Pressure - Pulmonary Artery
Catheter - Cardiac Output
Measurement - Tissue Oxygenation
- The assessment of the
Cardiovascular System - Arterial
Blood Pressure - Central Venous
Pressure - Pulmonary Artery
Catheter - Cardiac Output
Measurement - Tissue Oxygenation
- Hemodialysis
- Treatment done when the kidney
failure- artificial cleaning of the blood
- done to prevent acidosis
- Treatment done when the kidney
failure- artificial cleaning of the blood
- Critical Care
- Admission
- Method of
handling (Quality
of Care)
- Equipment
- Specialties
- Discharge
- Discharge
- Specialties
- Equipment
- Method of
handling (Quality
of Care)
- Admission
- Medically induced coma
- deep state of
unconsciousness, the
brain is able to rest and
swelling is more likely to
decrease. When swelling is
relieved, pressure on the
brain also reduces,
hopefully preventing some
or all brain damage from
occurring.
- deep state of
unconsciousness, the
brain is able to rest and
swelling is more likely to
decrease. When swelling is
relieved, pressure on the
brain also reduces,
hopefully preventing some
or all brain damage from
occurring.
- psychological effects
- PTSD
- marked by
increased stress
and anxiety
following
exposure to a
traumatic or
stressful event
- marked by
increased stress
and anxiety
following
exposure to a
traumatic or
stressful event
- Grief
- PTSD
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