Enterobacteria

Description

Mind Map on Enterobacteria, created by sam.hilton on 06/05/2013.
sam.hilton
Mind Map by sam.hilton, updated more than 1 year ago
sam.hilton
Created by sam.hilton about 11 years ago
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Resource summary

Enterobacteria
  1. Salmonella
    1. Cycle of transmission
      1. Salmonellosis
        1. Secretion system
          1. Type 1 & 2
          2. Effector proteins
            1. SopE
              1. Membrane ruffling
              2. SipA
                1. Aids process
                2. SipB
                  1. Induce inflammation
                  2. SopA
                    1. Neutrophils-inflammation
                    2. Sif
                      1. Forms filaments
                      2. Ssef
                        1. Redirests golgi traffic
                  3. Shigella
                    1. Shigellosis
                      1. Virulance factors
                        1. IpaC
                          1. Cdc42 & Rac1
                            1. Actin polymerisation
                          2. IpaD
                            1. lossens focal adhesions
                            2. VirA
                              1. Rho GTPases
                                1. Destabilises microtubules
                              2. VirF
                                1. Induces gene expression at 37
                                2. Shigella protrusions
                                  1. IcsA
                                    1. Binds N-WASP
                                3. Secretion system
                                  1. Type 3
                                    1. LPS glucosylation
                                4. Helicobacter Pylori
                                  1. Symptoms
                                    1. Gastic ulcers
                                      1. Duodenal ulcers
                                        1. Inflammation
                                          1. MALT lymphoma
                                            1. gastric carcinoma
                                          2. Virulence factors
                                            1. Flagella
                                              1. Urease
                                                1. Diagnosis
                                                  1. 13C urea test
                                                    1. pH sensitive biopsy
                                                  2. Adhesins
                                                    1. Secretion systems
                                                      1. Type 4
                                                      2. CagA toxins
                                                        1. SHP2 activated
                                                          1. Erk Map Kinase
                                                            1. Hummingbird phenotype
                                                              1. Increased motility
                                                          2. Vacuolating toxins
                                                            1. Hexameric pore
                                                              1. Apoptosis
                                                              2. P37
                                                                1. P58
                                                                2. LPS immune mimcry
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