nur nabila hanapi
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alexandria university year 2 2017

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nur nabila hanapi
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antibacterial chemotherapy

antibacterial chemotherapy

Question 1 of 41

1

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prepared synthetically in the lab

Explanation

Question 2 of 41

1

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Antibiotics are of of bacteria and fungi

Explanation

Question 3 of 41

1

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Classification of antibacterial agents

A- According to spectrum:
1- spectrum
2- spectrum

Explanation

Question 4 of 41

1

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Classification of antibacterial agents

B- According to the antibacterial effect
1-
2-

Explanation

Question 5 of 41

1

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Classification of antibacterial agents

C- According to mechanism of action:
1- Inhibition of
2- Inhibition of
3- Inhibition of
4- Inhibition of
5- Inhibition of

Explanation

Question 6 of 41

1

Target receptor for Inhibition of cell wall synthesis

Select one of the following:

  • Penicillin binding proteins

  • cytoplasmic membrane

  • Mycoplasma

  • Pseudomonas

Explanation

Question 7 of 41

1

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2 groups for Inhibition of cell wall synthesis

1. drugs
2. &

Explanation

Question 8 of 41

1

β Lactam drugs

Select one or more of the following:

  • Penicillin

  • cephalosporin

  • polymyxin

  • polyene

Explanation

Question 9 of 41

1

Penicillins & cephalosporins inhibit early precursors in transpeptidation

Select one of the following:

  • True
  • False

Explanation

Question 10 of 41

1

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& inhibit early precursors in transpeptidation

Explanation

Question 11 of 41

1

advantage of β Lactam drugs

Select one or more of the following:

  • Bactericidal

  • Selective toxicity

  • can act on non growing cells

Explanation

Question 12 of 41

1

bacitracin act only on growing cells

Select one of the following:

  • True
  • False

Explanation

Question 13 of 41

1

Inhibition of cell membrane function drugs

Select one or more of the following:

  • polymyxins

  • polyenes

  • Amikacin

  • Tetracyclines

Explanation

Question 14 of 41

1

Advantages of polymyxins & polyenes

1.
2.

Disadvantage of polymyxins & polyenes

1.

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    Bactericidal
    Selective toxicity
    can act on non growing cells
    bacteriostatic
    Toxic effects on kidney & CNS
    Act only on growing cells

Explanation

Question 15 of 41

1

Drugs acting on the 30S ribosomal subunit

Select one or more of the following:

  • Amikacin

  • Gentamicin

  • Tetracyclines

  • Lincomycin

  • Erythromycin

  • oleandomycin

Explanation

Question 16 of 41

1

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Aminoglycosides

1.
2.

Explanation

Question 17 of 41

1

Tetracyclines effective in treatment of Chlamydophila

Select one of the following:

  • True
  • False

Explanation

Question 18 of 41

1

oleandomycin is effective in treatment of intracellular bacteria

Select one of the following:

  • True
  • False

Explanation

Question 19 of 41

1

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Tetracyclines: Effective in treatment of intracellular bacteria e.g. &

Explanation

Question 20 of 41

1

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Aminoglycosides are ( Bactericidal, Bacteriostatic )

Explanation

Question 21 of 41

1

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Tetracyclines are ( Bacteriostatic, Bactericidal )

Explanation

Question 22 of 41

1

Drugs acting on the 50S ribosomal subunit except

Select one of the following:

  • Chloramphenicol

  • Lincomycin

  • Macrolides

  • polymyxins

Explanation

Question 23 of 41

1

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Drugs acting on the 50S ribosomal subunit are ( Bacteriostatic, Bactericidal )

Explanation

Question 24 of 41

1

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Macrolides

1.
2.

Explanation

Question 25 of 41

1

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Inhibition of nucleic acid synthesis

1.
2.

Explanation

Question 26 of 41

1

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Rifampin: inhibit

Explanation

Question 27 of 41

1

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Quinolones: inhibit

Explanation

Question 28 of 41

1

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( Rifampin, Quinolones, oleandomycin ): inhibit DNA dependent RNA polymerase

Explanation

Question 29 of 41

1

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Inhibition of bacterial metabolism

1.
2.

Explanation

Question 30 of 41

1

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Sulphonamides: inhibit

Explanation

Question 31 of 41

1

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Trimethoprim: inhibits

Explanation

Question 32 of 41

1

Trimethoprim: inhibits DHFA synthetase

Select one of the following:

  • True
  • False

Explanation

Question 33 of 41

1

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Bacterial Resistance to chemotherapeutic agents

1.
(natural/inherent)
2.
(acquired)

Explanation

Question 34 of 41

1

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Genetic origin (( acquired, inherent )) is ( Unpredictable, predictable )

Explanation

Question 35 of 41

1

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Genetic origin
()

1-
(=change in )
2-
( carrying destroying enzymes

Explanation

Question 36 of 41

1

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Non genetic origin
(/inherent)
,
1- Absence of cell wall ()
2- Permeability barrier in cell envelope ()
3- Non multiplying ()

Explanation

Question 37 of 41

1

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Mechanisms of Resistance

1.
2.
3. e.g.s, ,
4. ()

Explanation

Question 38 of 41

1

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Bacteria resistant to a drug may be resistant to a one.

Explanation

Question 39 of 41

1

Antibacterial Drug Combinations

1- ( 1 + 1= 1 )
2- (1 + 1 = 2 )
3- ( 1 + 1= 3 )
4- ( 1 + 1= 0 )

Drag and drop to complete the text.

    Indifference
    Addition
    Synergism
    Antagonism
    reciprocal
    commensal

Explanation

Question 40 of 41

1

Synergism

+
+ aminoglycoside
+

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    Penicillin
    Erythromycin
    aminoglycoside
    Rifampin
    Carbenicillin
    Chloramphenicol
    Ampicillin
    Tetracycline
    Metronidazole
    Macrolides

Explanation

Question 41 of 41

1

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Control of Drug Resistance

1- Give only when
2- Proper choice (according to )
3- Give in the proper for proper
(To prevent )
4- Use drug
(simultaneous use of 2 drugs)
5- Avoid of drugs

Explanation

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