CVS Physiology L3+4

Question 1 of 28

1

Fill the blank spaces to complete the text.

Shortening of the muscle occurs by the mechanism
- filaments slide along adjacent filaments by cycling of cross-bridges with myosin
• The lines come closer together and the muscle cell shortens
• The cardiac muscle thus produces or tension

Explanation

Question 2 of 28

1

Click on each orange point and write the correct answer.

Fill in the blanks

Explanation

Question 3 of 28

1

Fill the blank spaces to complete the text.

This ability of cardiac muscle to increase its force with a slight increase in its underlies its ability to control (the volume of blood ejected from the heart during a single beat)

Explanation

Question 4 of 28

1

If the muscle is overstretched (ie, during dilation of the heart), its ability to produce an active tension is reduced

Select one of the following:

True
False

Explanation

Question 5 of 28

1

Click on each orange point and write the correct answer.

Fill in the blanks

Explanation

Question 6 of 28

1

Click on the orange point and write the correct answer.

What is this curve an example of?

Explanation

Question 7 of 28

1

Click on each orange point and write the correct answer.

Label the graph with the following; increased, normal, decreased

Explanation

Question 8 of 28

1

Increased contractility means

Select one of the following:

higher stroke volume for the same end diastolic volume
lower stroke volume for the same end diastolic volume
higher stroke volume for the higer end diastolic volume
higher stroke volume for the lower end diastolic volume

Explanation

Question 9 of 28

1

A rise to a higher starling curve means decreased contractility

Select one of the following:

True
False

Explanation

Question 10 of 28

1

dP/dtmax is a good measure of

Select one of the following:

myocardial contractility
myocardial reponse
myocardial dilation
myocardial pressure

Explanation

Question 11 of 28

1

Click on each orange point and write the correct answer.

Label the following curves A, B and C

Explanation

Question 12 of 28

1

Fill the blank space to complete the text.

Agents that cause an increase in contractility are said to have a positive effect

Explanation

Question 13 of 28

1

Which of the following are examples of positive inotropic agents?

Select one or more of the following:

noradrenaline
adrenaline
digoxin
verapamil

Explanation

Question 14 of 28

1

Positive inotropic agents have the general effect of increasing

Select one of the following:

Ca^2+
K^+
Cl^-
Na^+

Explanation

Question 15 of 28

1

Which of the following are negative inotropic agents?

Select one or more of the following:

calcium channel blockers
beta adrenergic blockers
hypoxia
epinephrine

Explanation

Question 16 of 28

1

Click on each orange point and write the correct answer.

Fill in the blanks

Explanation

Question 17 of 28

1

Fill the blank space to complete the text.

CICR stands for

Explanation

Question 18 of 28

1

Fill the blank space to complete the text.

SERCA stands for calcium ATPase

Explanation

Question 19 of 28

1

Which of the following statements are true?

Select one or more of the following:

Junctional SR is studded with Ca2+ release channels
RYR is a giant protein with a terminal foot with a T-shaped tube in its centre through which Ca2+ ions are releases
The density of RYR is low near L-type Ca channels
The distance between the Ca channels and the RYR is very short (nm)

Explanation

Question 20 of 28

1

Click on each orange point and write the correct answer.

Fill in the blanks

Explanation

Question 21 of 28

1

What is SERCA regulated by?

Select one of the following:

phospholamban
ryanodine
CICR
noradrenaline

Explanation

Question 22 of 28

1

What happens at the end of contraction?

Select one or more of the following:

Ca2+ influx ceases and the SR is no longer stimulated to release Ca2+
the intracellular concentration of Ca2+ must be rapidly reduced
most of the cytoplasmic Ca2+ is pumped back into the SR by SERCA
a small amount of calcium is pumped out of the cell by the cell membrane Ca pump

Explanation

Question 23 of 28

1

What does sympathetic stimulation of the cardiac muscle produce?

Select one or more of the following:

Increase in active tension
Increase in the rate of active tension development
Increase in the rate of tension relaxation
Increase in passive tension
Increase in the rate of passive relaxation
decrease in active tension
decrease in passive tension

Explanation

Question 24 of 28

1

Click on each orange point and write the correct answer.

Fill in the blanks

Explanation

Question 25 of 28

1

Click on each orange point and write the correct answer.

Label the pink rectangles 1-12( step 2 is there twice). Label the blue ovals cardiac glycosides, catecholamine, troponin I, troponin C and phospolamban

Explanation

Question 26 of 28

1

Fill the blank space to complete the text.

cAMP activates

Explanation

Question 27 of 28

1

Fill the blank space to complete the text.

Protein Kinase A the L-type calcium channel

Explanation

Question 28 of 28

1

Which of the following are true?

Select one or more of the following:

Increased intracellular Ca2+ concentration increases the force of contraction (positive inotropic effect)
Protein kinase A phosphorylates Phospholamban and Troponin I
phosphorylation of troponin I leads to inhibition of binding of
calcium to troponin C and relaxation occurs
phosphorylation of phospholamban leads to reduced inhibition of SERCA which leads to increased uptake of calcium into the SR and relaxation occurs
Phospholamban phosphorylation promotes the rate of contraction

	Created by Rachel O' Flynn over 6 years ago

1st year college CVS Physiology Quiz on CVS Physiology L3+4, created by Rachel O' Flynn on 24/02/2018.

CVS Physiology L3+4

CVS Physiology L3+4

Question 1 of 28

Fill the blank spaces to complete the text.

Shortening of the muscle occurs by the mechanism - filaments slide along adjacent filaments by cycling of cross-bridges with myosin • The lines come closer together and the muscle cell shortens • The cardiac muscle thus produces or tension

Explanation

Question 2 of 28

Click on each orange point and write the correct answer.

Fill in the blanks

Explanation

Question 3 of 28

Fill the blank spaces to complete the text.

This ability of cardiac muscle to increase its force with a slight increase in its underlies its ability to control (the volume of blood ejected from the heart during a single beat)

Explanation

Question 4 of 28

If the muscle is overstretched (ie, during dilation of the heart), its ability to produce an active tension is reduced

Select one of the following:

Explanation

Question 5 of 28

Click on each orange point and write the correct answer.

Fill in the blanks

Explanation

Question 6 of 28

Click on the orange point and write the correct answer.

What is this curve an example of?

Explanation

Question 7 of 28

Click on each orange point and write the correct answer.

Label the graph with the following; increased, normal, decreased

Explanation

Question 8 of 28

Increased contractility means

Select one of the following:

Explanation

Question 9 of 28

A rise to a higher starling curve means decreased contractility

Select one of the following:

Explanation

Question 10 of 28

dP/dtmax is a good measure of

Select one of the following:

Explanation

Question 11 of 28

Click on each orange point and write the correct answer.

Label the following curves A, B and C

Explanation

Question 12 of 28

Fill the blank space to complete the text.

Agents that cause an increase in contractility are said to have a positive effect

Explanation

Question 13 of 28

Which of the following are examples of positive inotropic agents?

Select one or more of the following:

Explanation

Question 14 of 28

Positive inotropic agents have the general effect of increasing

Select one of the following:

Explanation

Question 15 of 28

Which of the following are negative inotropic agents?

Select one or more of the following:

Explanation

Question 16 of 28

Click on each orange point and write the correct answer.

Fill in the blanks

Explanation

Question 17 of 28

Fill the blank space to complete the text.

CICR stands for

Explanation

Question 18 of 28

Fill the blank space to complete the text.

SERCA stands for calcium ATPase

Explanation

Question 19 of 28

Which of the following statements are true?

Select one or more of the following:

Explanation

Question 20 of 28

Shortening of the muscle occurs by the mechanism
- filaments slide along adjacent filaments by cycling of cross-bridges with myosin
• The lines come closer together and the muscle cell shortens
• The cardiac muscle thus produces or tension