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Quiz on Antimicrobials, created by michalinawil on 15/09/2014.

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Antimicrobials

Question 1 of 8

1

What are four characteristics of penicillins?

Select one of the following:

  • - strong gram negative coverage
    - strengthens D-ala/D-ala of the bacterial cell wall
    - decreased hypersensitivity reactions
    - binds to transpeptidases

  • - sensitive to beta lactamases
    - poor gram negative coverage
    - decreased risk of hypersensitivity reactions
    - detaches from transpeptidases

  • - sensitive to beta lactamases
    - poor gram negative coverage
    - binds to transpeptidases
    - increased risk of hypersensitivity reactions

Explanation

Question 2 of 8

1

Which of the following drugs from the penicillin class is vulnerable to beta lactamases?

Select one of the following:

  • Penicillin G

  • Nafcillin

  • Zosyn

Explanation

Question 3 of 8

1

Which antibiotic is specifically indicated in treating Treponema pallidum (syphilis) and injected as a depot?

Select one of the following:

  • Mupirocin

  • Benzathine Penicillin G

  • Colisitin

  • Macrolides

Explanation

Question 4 of 8

1

The addition of amine groups to a drug will cause:

Select one of the following:

  • A decrease in affinity for gram negative cell membranes porins.

  • A decrease in affinity for gram positive cell membranes porins.

  • An increase in affinity for gram negative cell membrane porins.

  • An increase in affinity for gram negative cell membrane porins.

Explanation

Question 5 of 8

1

Ticaricillin is useful in treating gram negative bacteria in particular:

Select one of the following:

  • Pseudomonas

  • Anthrax

  • MRSA

  • Meningitis

Explanation

Question 6 of 8

1

Which of the cephalosporins are useful for treating meningitis?

Select one of the following:

  • 1st Generation (Cephazolin/Cephalexin)

  • 2nd Generation (Cefuroxime)

  • 3rd Generation (Ceftriaxone)

  • 4th Generation (Cefepime)

  • 5th Generation (Ceftaroline)

Explanation

Question 7 of 8

1

Which of the cephalosporins is useful in empiric coverage of nosocomial infections?

Select one of the following:

  • 1st Generation (Cephazolin/Cephalexin)

  • 2nd Generation (Cefuroxime)

  • 3rd Generation (Ceftriaxone)

  • 4th Generation (Cefepime)

  • 5th Generation (Ceftaroline)

Explanation

Question 8 of 8

1

Which correct group of drugs may be particularly useful in treating MRSA?

Select one of the following:

  • -Rifampin
    -Clindamycin
    -Metronidazole
    -Penicillin G
    -Vancomycin

  • -5th Generation Cephalosporin (Ceftaroline)
    -Vancomycin
    -Daptomycin
    -Linezolid
    -Mupirocin (Bactroban)

  • -Amoxicillin
    -Ciprofloxacin
    -Clindamycin
    -Gentamicin
    -Azithromycin

Explanation

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