Lect 4 -Concepts and terminology

Question 1 of 38

1

Flow rate is how much ❌ you are ❌ per unit of ❌

Drag and drop to complete the text.

urine

urea

time

distance

producing

consuming

voiding

Explanation

Question 2 of 38

1

GFR is the amount of ❌ going into ❌ per unit of ❌

Drag and drop to complete the text.

fluid

blood

bowmans capsule

the nephron

time

flow

Explanation

Question 3 of 38

1

what is normal glomerular flow rate?

Select one of the following:

100-130ml/min
500-600ml/min
200-300ml/min

Explanation

Question 4 of 38

1

Filtered load is the same as

Select one of the following:

tubular load
GFR
Plasma concentration of a solute
electrolytes

Explanation

Question 5 of 38

1

❌ / tubular load is the ❌ (❌) entering ❌.

Drag and drop to complete the text.

Filtered load

amount of a specific solute

electrolyte, glucose or amino acid

electrolyte, carbohydrate or protein

salt

bowman's capsule

the kidney

the nephron

Explanation

Question 6 of 38

1

Filtered Load can be calculated from ❌ and ❌

Drag and drop to complete the text.

GFR

blood flow

Plasma concentration of solute

blood concentration of solute

amount of urine produced

Explanation

Question 7 of 38

1

Inulin is....

Select one or more of the following:

freely filtered
not metabolised
not reabsorbed
not secreted

Explanation

Question 8 of 38

1

Inulin
The excretion rate = ...

Select one of the following:

excretion rate
filtration rate
absorption rate
consumption rate

Explanation

Question 9 of 38

1

PAH is ...

Select one or more of the following:

freely filtered
not metabolised
not reabsorbed
freely secreted

Explanation

Question 10 of 38

1

What does clearance less than 125ml/min indicate?

Select one of the following:

reabsorption
secretion

Explanation

Question 11 of 38

1

What does clearance more than 125ml/min indicate?

Select one of the following:

secretion
absorption

Explanation

Question 12 of 38

1

What can be used to experimentally measure GFR?

Select one of the following:

Inulin
glucose
PAH
calcium

Explanation

Question 13 of 38

1

What is elevated Pcr an indicator of?

Select one of the following:

reduced GFR
increased GFR
non changing GFR

Explanation

Question 14 of 38

1

Threshold is....

Select one or more of the following:

appearance of solute in urine before you reach the overall Transport maximum of the kidney
the plasma concentration at which a substance begins to appear in the urine
the tiny amount of solute appearing in urine when a single nephron reaches its maximum
the total transport maximum through out all of the nephrons in the kidney

Explanation

Question 15 of 38

1

what is transport maximum?

Select one or more of the following:

the total transport maximum through out all of the nephrons in the kidney
The point at which an amount of solute appears in urine when nephrons reaches its maximum
the plasma concentration at which a substance begins to appear in the urine
appearance of solute in urine before you reach the overall threshold of the kidney
The maximum rate of the solute shuttling done by transporters

Explanation

Question 16 of 38

1

How can renal function be measured?

Select one or more of the following:

imaging techniques
renal clearance

Explanation

Question 17 of 38

1

The ❌ clearance value of a certain substance is the ❌ which is ❌ by the kidney into urine ❌.

Drag and drop to complete the text.

renal

volume of plasma

volume of urine

cleared of this substance

/ min

Explanation

Question 18 of 38

1

What do we need to know to measure renal clearance?

Select one or more of the following:

volume of urine / min
concentration of the substance mg/ml urine
concentration of the substance mg/ml plasma
concentration of the substance mg/ml blood
volume of substrate / min

Explanation

Question 19 of 38

1

What properties does a substance used in a plasma clearance test have?

Select one or more of the following:

does not enter RBCs
does not affect normal renal function
should not be metabolized by the kidney
should be easily measured in plasma & urine
should be non toxic
should be easy to consume

Explanation

Question 20 of 38

1

What do we use renal clearance for?

Select one or more of the following:

measurement of GFR
measurement of the renal plasma flow rate
determining the renal handling of the different substances; whether or not the substance is reabsorbed or secreted by the renal tubules

Explanation

Question 21 of 38

1

What is the rate-limiting step in the tubular transport of glucose?

Select one of the following:

Na-glucose symport
glucose uniporter
glucose reabsorption
ca- glucose symport

Explanation

Question 22 of 38

1

The plasma leaving the kidney through the renal veins lacks .....

Select one of the following:

the substances that are eliminated in the urine
proteins
plasma
the substances that are not eliminated in the urine

Explanation

Question 23 of 38

1

What is creatinine?

Select one of the following:

the end product of creatine metabolism
the end product of creatinine metabolism
a phospholipid
dumped into the blood by smooth muscle

Explanation

Question 24 of 38

1

Creatinine is continuously dumped into the blood by....

Select one of the following:

smooth muscle
skeletal muscle
cardiac muscle

Explanation

Question 25 of 38

1

the rate of creatinine appearance in blood is proportional to a person's ....

Select one of the following:

muscle mass
fat mass
urine excretion
blood

Explanation

Question 26 of 38

1

Creatinine is....

Select one or more of the following:

freely filtered
not reabsorbed
reabsorbed
not freely filtered

Explanation

Question 27 of 38

1

how much creatinine is secreted by the proximal tubule?

Select one of the following:

10-20%
40-50%
70-80%
85-100%

Explanation

Question 28 of 38

1

There is a ______________ between plasma creatinine concentration and GFR.

Select one of the following:

inverse correlation
indirect correlation
direct relationship
direct correlation

Explanation

Question 29 of 38

1

What is the most common method used for routine GFR assessments?

Select one of the following:

creatinine clearance
inulin clearance
PAH clearance
Plasma clearance

Explanation

Question 30 of 38

1

If there are more solutes present than can be transported, the solutes will end up...

Select one of the following:

In urine
Reabsorbed
In the blood stream
Excreted in faeces

Explanation

Question 31 of 38

1

Renal clearance is comparison of ❌ rate of a substance to the rate of it's appearance in the ❌ i.e. Amount ❌ vs amount ❌. It gives info on ❌ and ❌

Drag and drop to complete the text.

filtration

urine

urea

blood

filtered

excreted

re-absorption

secretion

Explanation

Question 32 of 38

1

What percentage of clearance?

Drag the answer into the correct orange point.

A= ?% B=?% C=0% D=100%

A= 0% B=50% C=0% D=100%

A= 100% B=0% C=?% D=?%

A= 25% B=25% C=25% D=25%

Explanation

Question 33 of 38

1

Renal clearance principle is based on the principle of ❌ ❌. Input of X is ❌ output of X

Drag and drop to complete the text.

mass

balance

equal to

more than

less than

pressure

Explanation

Question 34 of 38

1

fill in the formula

Drag an answer into the correct orange point.

C

U

V

P

Explanation

Question 35 of 38

1

Tm for PAH secretory mechanism ~80mg/ml.
PPAH ❌ 80mg/ml = good estimation of RPF
PPAH ❌ 80mg/ml = poor estimation of RPF
At ❌ ❌: ❌ clearance ❌ RPF

Drag and drop to complete the text.

<

>

=

low

high

PPAH

PAH

Explanation

Question 36 of 38

1

Clearance units are ❌ per ❌

Drag and drop to complete the text.

volume

time

distance

meter

second

pressure

flow

Explanation

Question 37 of 38

1

Clearance is not the amount of the ❌ but instead the volume of ❌.

Drag and drop to complete the text.

substance removed

plasma from which it was removed

Explanation

Question 38 of 38

1

PAH is an abbreviation of ...

Select one of the following:

para-aminohippurate
pilo-acidic-hormone
pregacilohinutrate
primary acid hilute

	Created by Alannah McDonnell over 6 years ago

Quiz on Concepts and terminology, created by Alannah McDonnell on 22/03/2018.

Lect 4 -Concepts and terminology

Question 1 of 38

Flow rate is how much ❌ you are ❌ per unit of ❌

Drag and drop to complete the text.

Explanation

Question 2 of 38

GFR is the amount of ❌ going into ❌ per unit of ❌

Drag and drop to complete the text.

Explanation

Question 3 of 38

what is normal glomerular flow rate?

Select one of the following:

Explanation

Question 4 of 38

Filtered load is the same as

Select one of the following:

Explanation

Question 5 of 38

❌ / tubular load is the ❌ (❌) entering ❌.

Drag and drop to complete the text.

Explanation

Question 6 of 38

Filtered Load can be calculated from ❌ and ❌

Drag and drop to complete the text.

Explanation

Question 7 of 38

Inulin is....

Select one or more of the following:

Explanation

Question 8 of 38

Inulin The excretion rate = ...

Select one of the following:

Explanation

Question 9 of 38

PAH is ...

Select one or more of the following:

Explanation

Question 10 of 38

What does clearance less than 125ml/min indicate?

Select one of the following:

Explanation

Question 11 of 38

What does clearance more than 125ml/min indicate?

Select one of the following:

Explanation

Question 12 of 38

What can be used to experimentally measure GFR?

Select one of the following:

Explanation

Question 13 of 38

What is elevated Pcr an indicator of?

Select one of the following:

Explanation

Question 14 of 38

Threshold is....

Select one or more of the following:

Explanation

Question 15 of 38

what is transport maximum?

Select one or more of the following:

Explanation

Question 16 of 38

How can renal function be measured?

Select one or more of the following:

Explanation

Question 17 of 38

The ❌ clearance value of a certain substance is the ❌ which is ❌ by the kidney into urine ❌.

Drag and drop to complete the text.

Explanation

Question 18 of 38

What do we need to know to measure renal clearance?

Select one or more of the following:

Explanation

Question 19 of 38

What properties does a substance used in a plasma clearance test have?

Select one or more of the following:

Explanation

Question 20 of 38

What do we use renal clearance for?

Inulin
The excretion rate = ...

Tm for PAH secretory mechanism ~80mg/ml.
PPAH ❌ 80mg/ml = good estimation of RPF
PPAH ❌ 80mg/ml = poor estimation of RPF
At ❌ ❌: ❌ clearance ❌ RPF