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Created by J yadonknow
over 6 years ago
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Intercellular communcation
Paracrine
Autocrine
Endocrine
Juxtacrine
Cell influence response
Cell signalling for cell surface R's (9)
Modification of proteins for signal transduction
How is this tightly regulated?
Termination of Signal (3)
Eliminate EC ligand
Deactivate signal transduction proteins
Remove +R from PCM via Endocytosis
Natural endogenous kinases (3)
Epinephrine/histamine are
Prostaglandins are
Glucagon and insulin are
Hormones detected by IC R
Cytokines are
3 Examples
IITNF
What's their function
Growth factors are
What type of signalling do they employ?
What's their function?
Agonist
Antagonists
Degrees of agonist action
Factors of drug action (2)
What is affinity?
What is their intrinsic action?
What does a value of 1 mean?