Rebecca  Kaspers
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Ahea 100 Pharmacology

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Rebecca  Kaspers
Created by Rebecca Kaspers over 6 years ago
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Neurologic and Neuromuscular Drugs

Question 1 of 20

1

Physical and psychological dependence are major adverse effects of direct-acting skeletal muscle relaxants.

Select one of the following:

  • True
  • False

Explanation

Question 2 of 20

1

Direct-acting skeletal muscle relaxants interfere with __________ ions involved in skeletal muscle contraction.

Select one of the following:

  • calcium

  • phosphorus

  • sodium

  • magnesium

Explanation

Question 3 of 20

1

Neuromuscular blocking drugs work by:

Select one of the following:

  • a. disrupting nerve impulses at motor end plates

  • b. disrupting nerve impulses at post-synaptic neurons

  • c. both the above are true

Explanation

Question 4 of 20

1

Depolarizing neuromuscular blocking drugs are derived from curare alkaloids.

Select one of the following:

  • True
  • False

Explanation

Question 5 of 20

1

The __________ is that area where a terminal nerve ending innervates a muscle.

Select one of the following:

  • a. motor end plate

  • b. synaptic cleft

  • c. both the above are true

Explanation

Question 6 of 20

1

Curare alkaloids:

Select one of the following:

  • Paralyze the diaphragm preventing breathing

  • Cross the blood-brain-barrier

  • Make one go unconscious immediately

  • Compete with phosphorus involved in muscle contraction

Explanation

Question 7 of 20

1

The antidote for curare alkaloids are __________ drugs.

Select one of the following:

  • anti-cholinesterase

  • cholinesterase

Explanation

Question 8 of 20

1

Depolarizing neuromuscular blocking drugs cannot be inactivated by cholinesterase.

Select one of the following:

  • True
  • False

Explanation

Question 9 of 20

1

Succinylcholine is metabolized slower than acetylcholine, resulting in:

Select one of the following:

  • Longer muscle paralysis

  • Shorter muscle paralysis

  • Succinylcholine has nothing to do with muscle paralysis

Explanation

Question 10 of 20

1

Parkinson’s disease:

Select one of the following:

  • a. has a deficiency of dopamine

  • b. has an excess of acetylcholine

  • c. is a movement disorder

  • d. all the above are true

Explanation

Question 11 of 20

1

Akinesia is the absence of:

Select one of the following:

  • the power of voluntary movement

  • the ability to think

  • diaphragmatic movement

  • the ability of speech

Explanation

Question 12 of 20

1

The 2 types of therapy for Parkinson’s disease are __________ and __________ drugs.

Select one of the following:

  • anti-cholinergic; dopaminergic

  • anti-cholinergic; anti-cholinesterase

  • cholinergic; dopaminergic

  • cholinergic; anti-cholinesterase

Explanation

Question 13 of 20

1

Another name for anti-cholinergic drugs is __________ drugs.

Select one of the following:

  • parasympatholytic

  • sympatholytic

Explanation

Question 14 of 20

1

Too much acetylcholine will excite the CNS causing parkinsonian tremor.

Select one of the following:

  • True
  • False

Explanation

Question 15 of 20

1

Dopaminergic drugs act on the brain to improve motor function.

Select one of the following:

  • True
  • False

Explanation

Question 16 of 20

1

Levodopa can convert to dopamine:

Select one of the following:

  • before crossing the blood-brain-barrier

  • after crossing the blood-brain-barrier

  • both the above are true

Explanation

Question 17 of 20

1

COMT inhibitors are reversible.

Select one of the following:

  • True
  • False

Explanation

Question 18 of 20

1

Triptans are used to treat:

Select one of the following:

  • musculoskeletal issues

  • migraines

  • seizures

  • Parkinson’s disease

Explanation

Question 19 of 20

1

5-HT1-receptor agonists and ergotamine preparations are both used in the treatment of:

Select one of the following:

  • migraines

  • musculoskeletal issues

  • seizures

  • Parkinson’s disease

Explanation

Question 20 of 20

1

Abortive anti-migraine drugs are designed to stop a migraine:

Select one of the following:

  • a. after it starts

  • b. before it starts

  • c. both the above are correct

  • d. neither of the above are correct

Explanation