MC Cancer in Women

MCC of cancer related death in women

MC Cancer in Men

MC cancer related death in men

Most important prognostic indicator for Lung CA and Breast CA devoid of systemic metastasis

Most important prognostic indicator for sarcoma devoid systemic mets

What is a PET scan?

Causes of False Positives on PET Scan

Causes of False Negatives with PET Scan

Hyperplasia

Metaplasia
give an example

Dysplasia

Core Needle Biopsy
vs Fine Needle Biopsy

CEA

AFP

CA 19-9

CA 125

Tumor Marker
beta-HCG

PSA

Tumor Marker NSE

BRCA I and II

Tumor Marker Chromogranin A

Ret Oncogene

half life of CEA

half life of PSA

half life of AFP

Cancer Transformation

Latency Period

What are Proto-oncogenes?

Human Papillomavirus is associated with which Malignancy?

Helicobacter Pylori is associated with what malignancy?

Hepatitis B and C viruses are associated with which malignancy?

EBV is associated with which malignancies?

What is the most vulnerable stage of cell cycle for XRT?

Higher-energy Radiation

Fractionate XRT doses

Very Radiosensitive Tumors

Very Radioresistant Tumors

Brachytherapy

Gamma Knife

Cell Cycle-specific Agents

Cell Cycle-Nonspecific Agents

Tamoxifen

Taxol
MoA and Side Effect

Side Effect of Bleomycin and Busulfan

Cisplatin
& side effects

Carboplatin
& side effects

Vincristine
& side effects

Vinblastine
& side effects

Cyclophosphamide
& side effects

Medication to use with Cyclophosphamide to prevent hemorrhagic cystitis

Levamisole

Methotrexate
& side effects

Leucovorin

5-Fluorouracil

Doxorubicin
& side effects

MoA of Etoposide

GCSF
& side effects

Sweet's Syndrome

When would you resect a normal breast to prevent cancer?

When would you resect a normal thyroid to prevent cancer?

List Tumor Suppressor Genes

List of proto-oncogenes

Retinoblastoma gene

p53

APC

DCC

bcl

BRCA

ras

src

sis

erb B

myc

Li-Fraumeni Syndrome

Genes involved in colon CA

Cancers associated with Coal tar

Cancers associated with Beta-naphthylamine

Cancers associated with Benzene

Cancers Associated with Asbestos

Troisier sign

Cancers associated with suspicious supraclavicular nodes

Cancers associated with
suspicious axillary node

Sister Mary Joseph Node

Metastases to the ovaries, what are the 2 MC primary cancers from?

MC primary sites of bone mets

MC primary cancer with skin mets

MC primary cancer with small bowel metastases

Question that is answered in phase 1 clinical trial

Question that is answered in phase 2 clinical trial

Question that is answered in phase 3 clinical trial

what is phase 4 clinical trial

What is induction therapy?

What is primary (Neoadjuvant) chemotherapy?

What is adjuvant therapy?

What is salvage therapy?

En bloc multiorgan resection

Sentinel LN Biopsy

Most successfully cured metastasis with surgery

a tumor that surgical debulking can improve chemotherapy

curable solid tumors with chemotherapy onlly

Name 2 T-cell Lymphomas

HIV related malignancies