Jennifer Keough
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Jennifer Keough
Created by Jennifer Keough almost 6 years ago
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Neurologic and Neuromuscular Drugs

Neurologic and Neuromuscular Drugs

Question 1 of 38

1

Centrally-acting skeletal muscle relaxants are basically Central Nervous System depressants.

Select one of the following:

  • True
  • False

Explanation

Question 2 of 38

1

Direct-acting skeletal muscle relaxants affect:

Select one of the following:

  • a. skeletal muscle

  • b. cardiac muscle

  • c. smooth muscle

  • d. all the above are true

Explanation

Question 3 of 38

1

Neuromuscular blocking drugs work by:

Select one of the following:

  • a. disrupting nerve impulses at motor end plates

  • b. disrupting nerve impulses at post-synaptic neurons

  • c. both the above are true

Explanation

Question 4 of 38

1

Depolarizing neuromuscular blocking drugs are derived from curare alkaloids.

Select one of the following:

  • True
  • False

Explanation

Question 5 of 38

1

The ________________ is that area where a terminal nerve ending innervates a muscle.

Select one of the following:

  • a. motor end plate

  • b. synaptic cleft

  • c. both the above are true

Explanation

Question 6 of 38

1

Curare alkaloids:

Select one of the following:

  • Paralyze the diaphragm preventing breathing

  • cross the blood-brain-barrier

  • make one go unconscious immediately

  • compete with phosphorus involved in muscle contractions

Explanation

Question 7 of 38

1

The antidote for curare alkaloids are ____________ drugs.

Select one of the following:

  • anti-cholinesterase

  • cholinesterase

Explanation

Question 8 of 38

1

Depolarizing neuromuscular blocking drugs cannot be inactivated by cholinesterase.

Select one of the following:

  • True
  • False

Explanation

Question 9 of 38

1

Succinylcholine is metabolized slower than acetylcholine, resulting in:

Select one of the following:

  • Longer muscle paralysis

  • Shorter muscle paralysis

  • Succinylcholine has nothing to do with muscle paralysis

Explanation

Question 10 of 38

1

What are the movement disorders associated with Parkinson's disease?

Select one of the following:

  • a. Muscle rigidity

  • b. Akinesia

  • c. Tremors at rest

  • d. Posture/balance disturbances

  • e. a and d are correct

  • f. c and d are correct

  • g. All the above are correct

Explanation

Question 11 of 38

1

Akinesia is the absence of:

Select one of the following:

  • the power of voluntary movement

  • the ability to think

  • diaphragmatic movement

  • the ability of speech

Explanation

Question 12 of 38

1

The 2 types of therapy for Parkinson's disease are _____________ and ______________ drugs.

Select one of the following:

  • anti-cholinergic; dopaminergic

  • anti-cholinergic; anti-cholinesterase

  • cholinergic; dopaminergic

  • cholinergic; anti-cholinersterase

Explanation

Question 13 of 38

1

Anti-cholinergic drugs inhibit acetylcholine action at parasympathetic receptors.

Select one of the following:

  • True
  • False

Explanation

Question 14 of 38

1

Too much acetylcholine will excite the CNS causing parkinsonian tremor.

Select one of the following:

  • True
  • False

Explanation

Question 15 of 38

1

Dopaminergic drugs act on the brain to improve motor function.

Select one of the following:

  • True
  • False

Explanation

Question 16 of 38

1

Dopaminergic drugs act on the brain to improve motor function.

Select one of the following:

  • True
  • False

Explanation

Question 17 of 38

1

Lavodopa can convert to dopamine:

Select one of the following:

  • a. before crossing the blood-brain-barrier

  • b. after crossing the blood-brain-barrier

  • c. both the above are true

Explanation

Question 18 of 38

1

COMT stands for:

Select one of the following:

  • a. Catechol-O-methyltransferase

  • b. Catechol-OH-methyltransacetylase

  • c. Catecholamine-O-methyltransacetylase

  • d. none of the above are correct

Explanation

Question 19 of 38

1

Another name of 5-HT1-receptor agonists is triptans.

Select one of the following:

  • True
  • False

Explanation

Question 20 of 38

1

5-HT1-receptor agonists and ergotamine preparations are both used in the treatment of:

Select one of the following:

  • migraines

  • musculoskeletal issues

  • seizures

  • Parkinson's disease

Explanation

Question 21 of 38

1

Depolarizing neuromuscular blocking drugs act like ____________.

Select one of the following:

  • acetylcholine

  • norepinephrine

  • epinephrine

  • dopamine

Explanation

Question 22 of 38

1

Physical and psychological dependence are major adverse effects of direct-acting skeletal muscle relaxants.

Select one of the following:

  • True
  • False

Explanation

Question 23 of 38

1

Direct-acting skeletal muscle relaxants interfere with ___________ ions involved in skeletal muscle contraction:

Select one of the following:

  • sodium

  • calcium

  • magnesium

  • phosphorus

Explanation

Question 24 of 38

1

Parkinson's disease:

Select one of the following:

  • a. has a deficiency of dopamine

  • b. has an excess of acetylcholine

  • c. is a movement disorder

  • d. all the above are true

Explanation

Question 25 of 38

1

Another name for anti-cholinergic drugs is ____________ drugs.

Select one of the following:

  • parasympatholytic

  • sympatholytic

Explanation

Question 26 of 38

1

COMT inhibitors are reversible.

Select one of the following:

  • True
  • False

Explanation

Question 27 of 38

1

Triptans are used to treat:

Select one of the following:

  • seizures

  • musculoskeletal issues

  • Parkinson's disease

  • migraines

Explanation

Question 28 of 38

1

Abortive anti-migraine drugs are designed to stop a migraine:

Select one of the following:

  • a. after it starts

  • b. before it starts

  • c. both the above are correct

  • d. neither of the above are correct

Explanation

Question 29 of 38

1

Levodopa needs passage through the blood-brain-barrier to become effective.

Select one of the following:

  • True
  • False

Explanation

Question 30 of 38

1

Carbidopa enhances the effectiveness of Levodopa by preventing its peripheral conversion to dopamine.

Select one of the following:

  • True
  • False

Explanation

Question 31 of 38

1

COMT inhibitors are used in Parkinson patients when the initial therapy begins to wear off.

Select one of the following:

  • True
  • False

Explanation

Question 32 of 38

1

Contraindication for taking triptans includes:

Select one of the following:

  • a. Ischemic

  • b. Cerebrovascular

  • c. Coronary artery disease

  • d. All the above are correct

Explanation

Question 33 of 38

1

Anti-cholinergic drugs inhibit acetylcholine action at sympathetic receptors.

Select one of the following:

  • True
  • False

Explanation

Question 34 of 38

1

For epilepsy and seizures a(an) ______________ drug is usually recommended.

Select one of the following:

  • a. anti-migraine

  • b. COMT inhibitor

  • c. dopaminergic

  • d. anti-convulsant

Explanation

Question 35 of 38

1

To have a higher conversion to dopamine after passing through the blood-brain-barrier, one needs to take ______________.

Select one of the following:

  • a. Levodopa

  • b. Carbidopa

  • c. Levodopa and Carbidopa

  • d. None of the above drugs have anything to do with dopamine

Explanation

Question 36 of 38

1

Anti-convulsant drugs:

Select one of the following:

  • a. Stabilize nerve cells from over excitement

  • b. Elevate seizure thresholds

  • c. Inhibit neuromuscular transmission

  • d. Increase GABA

  • e. All the above are correct

Explanation

Question 37 of 38

1

The neurotransmitter released at motor end plates is:

Select one of the following:

  • a. Norepinephrine

  • b. Dopamine

  • c. Acetylcholine

  • d. Epinephrine

Explanation

Question 38 of 38

1

The effectiveness of ergotamine preparations is increased by drinking coffee.

Select one of the following:

  • True
  • False

Explanation

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