Rochelle T
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Lec 19, October 30th Gene regulation in Eukaryotes.

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Rochelle T
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Genetics Final Exam-LEC 19

Genetics Final Exam-LEC 19

Question 1 of 10

1

What is the function of lac Y?

Select one of the following:

  • B-Galactosidase activity

  • Permease activity

  • transacetylase activity

  • methyltransferase activity

Explanation

Question 2 of 10

1

Allolactose binds to the promoter

Select one of the following:

  • True

  • False

Explanation

Question 3 of 10

1

In bacteria with genotype I+P+O+Z+Y+A+, in the presense of lactose and presense of glucose, which of the following is/are true?

Select one of the following:

  • Transcription in on

  • Transcription is off

  • The CAP site is not occupied

  • Two of the above

  • none of the above

Explanation

Question 4 of 10

1

Allolactose and lactose differ in the formation/type of the glycosidic bond.

Select one of the following:

  • True
  • False

Explanation

Question 5 of 10

1

In bacteria with genotype I+P+ O^C Z+Y+A+, in the presence of lactose and absence of glucose, which of the following is/are false?

Select one of the following:

  • Transcription is off

  • The repressor does not bind to the operator

  • The CAP site is unoccupied

  • The inducer is present

  • Two of the above

Explanation

Question 6 of 10

1

Chromatin remodeling complexes alter nucleosomes, this occurs when:

Select one of the following:

  • Compleses of ATP dependent protein degrade histones and release the DNA from nucleosomes

  • complexes of ATP dependent proteins may reposition, evict or change nucleosome composition

  • remodeling proteins bind to TFIID to promote or inhibit nucleosome formation

  • remodeling proteins increase the supercoiling of the DNA, which can inhibit nucleosome formation

Explanation

Question 7 of 10

1

: (Gene)Regulatory transcription factors activate or inhinit transcription. The arrangements and composition of nucleosomes influence transcription. DNA methylation (usually) inhibits transcription.
: (pre-RNA)Alternative splicing alters exon choices. RNA editing alters the base sequence of mRNAs
: (mRNA) Small RNAs, called miRNAs and siRNAs, silence the translation of mRNA. Proteins that bind to the 5' end of mRNA regulate translation. mRNA stability may be influenced by RNA binding proteins
: (Protein) Feedback inhibition and covalent modifications regulate protein function.
Finally a Functional protein

Drag and drop to complete the text.

    Transcription
    RNA processing
    Translation
    Posttranslation modification

Explanation

Question 8 of 10

1

What are some types of the molecular changes that undelie epigenetic gene regulation?

Select one of the following:

  • DNA methylation and depurination of cytosine residues

  • depurination and chromatin remodeling

  • DNA methylation and chromatin remodeling

  • depurination of cytosine and thymidine residues

Explanation

Question 9 of 10

1

DNA that contains actively transcribed genes would most likely contain chromatin in the closed configuration.

Select one of the following:

  • True
  • False

Explanation

Question 10 of 10

1

Which of the following mRNAs would be degraded the most rapidly?

Select one of the following:

  • an mRNA with 200 adenine residues at its 3' end

  • an mRNA with multiple AAUUU sequences in its 3' untranslated region and with 10 adenine residues at the 3' end

  • an mRNA with 100 adenine residues at its 3' end

  • an mRNA with multiple AAUUU sequences in its 3' untranslated region and with 200 adenine residues at the 3' end

Explanation

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