Berfin Miiau
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Quiz on Pharmacology , created by Berfin Miiau on 24/12/2018.

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Berfin Miiau
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Pharmacology

Question 1 of 35

1

the main routes of enteral administration of drugs are

Select one or more of the following:

  • oral

  • by injection

  • rectal

  • per mucosa

Explanation

Question 2 of 35

1

Advantages of the oral route of drug administration are

Select one or more of the following:

  • easily self-administered

  • toxicity and overdose may be overcome with antidotes

  • drugs avoid first-pass metabolism

  • drugs go directly into the systemic circulation

Explanation

Question 3 of 35

1

Advantages of the rectal route of drug administration are

Select one or more of the following:

  • suitable for vomiting patients

  • suitable for children

  • suitable for unconscious patients

  • a way to avoid first-pass metabolism

Explanation

Question 4 of 35

1

Disadvantages of iv drug administration are

Select one or more of the following:

  • a trained staff is required

  • risk of bacterial contamination at the site of injection

  • it is painful and stressful for the patient

  • drugs undergo first-pass metabolism in the liver

Explanation

Question 5 of 35

1

Point out the correct statements for iv drug administration

Select one or more of the following:

  • aqueous solutions can be administered iv

  • oil solutions can be administered iv

  • has the highest bioavailability

  • used for treatment of life-threatening conditions

Explanation

Question 6 of 35

1

The subject of pharmacokinetics is

Select one or more of the following:

  • drug absorption and distribution

  • drug biotransformation

  • drug elimination

  • drug biological activity

Explanation

Question 7 of 35

1

Point out the correct statements for passive diffusion

Select one or more of the following:

  • does not require energy

  • requires energy

  • involves a carrier

  • drugs move from high to lower concentration

Explanation

Question 8 of 35

1

The diffusion of lipid soluble drugs

Select one or more of the following:

  • depends on the charge of the drug molecule

  • does not depend on the charge of the drug molecule

  • is penetration through aqueous channels or pores

  • is penetration through the biological membranes

Explanation

Question 9 of 35

1

A drug-weak acid will be absorbed

Select one or more of the following:

  • in a medium with low pH

  • in a medium with high pH

  • in the stomach

  • in the intestine

Explanation

Question 10 of 35

1

A drug-weak base will be absorbed

Select one or more of the following:

  • in a medium with low pH

  • in a medium with high pH

  • in the stomach

  • in the intestine

Explanation

Question 11 of 35

1

Point out the correct statements for active drug transport

Select one or more of the following:

  • it is energy- dependent

  • it is not energy- dependent

  • requires carriers

  • does not require carriers

Explanation

Question 12 of 35

1

Point out the correct statement for drugs bound to plasma proteins

Select one or more of the following:

  • bound drugs are pharmacologically active

  • only the unbound drugs can act on target sites in the tissues

  • only the bound drugs are available to the process of elimination

  • drugs may displace each other from the binding proteins

Explanation

Question 13 of 35

1

Drug metabolism may

Select one or more of the following:

  • increase a drug's pharmacological activity

  • decrease a drug's pharmacological activity

  • change the pharmacological effects of a drug

  • change the toxicity of a drug

Explanation

Question 14 of 35

1

first phase liver metabolism reactions include

Select one or more of the following:

  • acetylation

  • conjugation

  • reduction

  • oxidation

Explanation

Question 15 of 35

1

Second phase liver metabolism reactions include

Select one or more of the following:

  • acetylation

  • conjugation

  • reduction

  • oxidation

Explanation

Question 16 of 35

1

Phase I of drug metabolism

Select one or more of the following:

  • may or may not involve cytochrome P450 system

  • phase I reactions convert lipophilic molecules to more polar molcecules

  • includes alcohol dehydrogenation, amine oxidation, hydrolysis

  • consists of conjugation reactions

Explanation

Question 17 of 35

1

Renal excretion of a drug will be reduced if

Select one or more of the following:

  • the drug is a weak acid and the urine is alkaline

  • the drug is a weak acid and the urine is acidic

  • the drug is a weak base and the urine is alkaline

  • the drug is a barbiturate and the urine is alkaline

Explanation

Question 18 of 35

1

Drug pharmacodynamics includes

Select one or more of the following:

  • drug effects

  • mechanisms of drug action

  • drug elimination

  • how the organism changes drugs

Explanation

Question 19 of 35

1

The changes that occur due to the interaction between drug molecules and organism structures are called

Select one or more of the following:

  • drug effect

  • drug action

  • adverse drug reaction

  • placebo effect

Explanation

Question 20 of 35

1

The organism response as a result of the changes that have occured due to its interaction with the drug is called

Select one or more of the following:

  • drug action

  • drug effect

  • adverse drug reaction

  • placebo effect

Explanation

Question 21 of 35

1

What is characteristic for a drug receptor

Select one or more of the following:

  • induces (generates) a change in organism functions

  • has selectivity

  • has sensitivity

  • has specifity

Explanation

Question 22 of 35

1

Agonists are ligands which

Select one or more of the following:

  • have affinity

  • block receptors

  • have intrinsic activity

  • bind to the receptor

Explanation

Question 23 of 35

1

Antagonists are ligands which

Select one or more of the following:

  • have strong affinity

  • have intrinsic activity

  • block the receptor

  • do not have intrinsic activity

Explanation

Question 24 of 35

1

Therapeutic margin is the

Select one or more of the following:

  • difference between maximal toxic and minimal therapeutic doses

  • ratio between minimal toxic and minimal therapeutic doses

  • difference between mean lethal and mean effective doses

  • ratio between lethal and mean effective doses

Explanation

Question 25 of 35

1

Drugs' therapeutic index is the

Select one or more of the following:

  • difference between minimal toxic and minimal therapeutic doses

  • ratio between minimal toxic and minimal therapeutic doses

  • difference between mean lethal and mean effective doses

  • ratio between mean lethal and mean effective doses

Explanation

Question 26 of 35

1

Types of drug interaction are

Select one or more of the following:

  • synergy

  • antagonism

  • synergy/ antagonism

  • chemical antagonism (formation of complexes)

Explanation

Question 27 of 35

1

Potentiation can be observed during the concomitant use of

Select one or more of the following:

  • Fentanyl and Droperidol

  • Heparin and Protamine

  • Amoxicillin and Clavulonic acid

  • Diazepam and Flumazenil

Explanation

Question 28 of 35

1

Full competitive antagonist of opioid receptors, administered in acute opioid intoxication is

Select one or more of the following:

  • Allylnormorphine

  • Methadone

  • Naloxone

  • Flumazenil

Explanation

Question 29 of 35

1

Chemical antagonism or complex formation can be observed in

Select one or more of the following:

  • Morphine and Naloxone

  • Diazepam and Flumazenil

  • Epinephrine and Histamine

  • Iron preparation and Deferroxamine

Explanation

Question 30 of 35

1

Which of the following are enzyme inducers

Select one or more of the following:

  • Phenytoin

  • Phenobarbital

  • Metamizol

  • Metronidazole

Explanation

Question 31 of 35

1

Multiple drug administration could lead to

Select one or more of the following:

  • drug tolerance

  • drug dependence

  • drug accumulation

  • allergic reactions

Explanation

Question 32 of 35

1

Drug addicition/ dependence involves

Select one or more of the following:

  • drug tolerance

  • physical dependence

  • psychological dependence

  • allergy

Explanation

Question 33 of 35

1

Antiseptics are used for

Select one or more of the following:

  • decontamination of laundry and sanitary facilities

  • decontamination of skin and mucous membranes

  • internal administration

  • treatment of fever

Explanation

Question 34 of 35

1

Disinfectants are used for decontamination of

Select one or more of the following:

  • urine, faeces and other

  • mouth

  • instruments

  • clothing and underwear

Explanation

Question 35 of 35

1

Antiseptics and disinfectants are

Select one or more of the following:

  • detergents

  • barbiturates

  • oxidizing agents and halogen derivatives

  • phenols

Explanation

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