Catriona Wilds
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Quiz on Psychopharmacology, created by Catriona Wilds on 27/02/2019.

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Catriona Wilds
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Psychopharmacology

Question 1 of 15

1

The primary excitatory neurotransmitter is ______, and ______ is the primary inhibitory neurotransmitter.

Select one of the following:

  • GABA, Glutamate

  • Glutamate, GABA

  • Dopamine, Serotonin

  • Adrenaline, Opiate

Explanation

Question 2 of 15

1

An agonist is a drug that...

Select one of the following:

  • Is always less potent than an antagonist

  • Elicits a similar physiological response to that of a neurotransmitter

  • Will usually have depressant effects

  • All of the above

Explanation

Question 3 of 15

1

The anti-depression drug Fluoxetine (also known as Prozac) increases level of serotonin. It does this by...

Select one of the following:

  • increasing serotonin production

  • inhibiting serotonin deterioration

  • indirect stimulation of serotonic cells

  • blocking the reuptake of synaptic serotonin

Explanation

Question 4 of 15

1

An increase in _____ for a drug would cause that drug to more rapidly reach the brain.

Select one of the following:

  • Metabolism of the drug via the liver

  • Lipid solubility

  • Water solubility

  • Kidney excretion

Explanation

Question 5 of 15

1

One mechanism for the tolerance produced by repeated drug administration is...

Select one of the following:

  • A decreased metabolism of the drug

  • An increased plasma level of the drug

  • An increased number of receptors for the drug

  • A reduced number of receptors for the drug

Explanation

Question 6 of 15

1

Caffeine acts to...

Select one of the following:

  • Block adenosine receptors

  • Stimulate adenosine receptors

  • Block noradrenaline receptors

  • Block acetylcholine receptors

Explanation

Question 7 of 15

1

The psychoactive constituent of the drug cannabis (THC) probably acts on the same receptors as...

Select one of the following:

  • Adenosine

  • Anandamide

  • Adenylate cyclase

  • Arachidonic cannabinol

Explanation

Question 8 of 15

1

Naloxone would be effective at reversing the effects of...

Select one of the following:

  • Dextro-amphetamine

  • LSD

  • Morphine

  • Both LSD and Morphine

Explanation

Question 9 of 15

1

Repeated administration of barbiturates/opiates may cause no increase in level of sedation/pain relief but an increasing effect on respiratory depression. Why might this be?

Select one of the following:

  • The drug begins to act as a placebo

  • The drug has an increased margin of safety over time

  • The drug has more than one site of action

  • The drug binds with an ionotropic receptor

Explanation

Question 10 of 15

1

Drugs that are postsynaptic receptor antagonists...

Select one of the following:

  • Increase neural inhibition only

  • Reduce neural inhibition only

  • Increase or reduce neural inhibition depending on the typical action of the neurotransmitter

  • Increase neural inhibition only when bound to a metabotropic receptor

Explanation

Question 11 of 15

1

A drug which prevents the storage of a neurotransmitter within synaptic vesicles would be...

Select one of the following:

  • An agonist

  • An antagonist

  • Either an agonist or an antagonist

  • An agonist only when calcium channels are open

Explanation

Question 12 of 15

1

If a drug blocks pre-synaptic transporter reuptake molecules, then it is...

Select one of the following:

  • An agonist

  • An antagonist

  • Either an agonist or an antagonist

  • An agonist only when sodium channels are open

Explanation

Question 13 of 15

1

Repeated stimulation of the mesolimbic system can lead to drug abuse. This is because...

Select one of the following:

  • This system projects to the prefrontal cortex

  • This system is important for reinforcement

  • This is an important part of the basal ganglia

  • This system is important in the control of the mood

Explanation

Question 14 of 15

1

GABA receptors are complex, but it is known that alcohol will act as...

Select one of the following:

  • An agonist to these receptors

  • An antagonist to these receptors

  • Either an agonist or an antagonist to these receptors

  • An agonist but only if steroid molecules are also bound to the receptor

Explanation

Question 15 of 15

1

Why might terahydrocannabinol (THC), the active ingredient in marijuana) be used by people taking certain drugs for cancer?

Select one of the following:

  • It reduces anxiety produced by cancer drugs

  • It acts as an antagonist for the neurotransmitter anandamide

  • It reduces nausea produced by cancer drugs

  • All of the above

Explanation

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