Uterine Cancer

Question 1 of 22

1

Select from the dropdown list to complete the text.

Endometrial polyps are a common cause of dysfunctional uterine bleeding and typically occur in ( post-menopausal, pre-pubertal, pre-menopausal ) women.

Explanation

Question 2 of 22

1

Select from the dropdown lists to complete the text.

The peak incidence of endometrial carcinoma is ( 50-60 years, 30-40 years, 70-80 years ).
It is uncommon for endometrial carcinoma to present in those ( under 40, over 65 )

Explanation

Question 3 of 22

1

Fill the blank space to complete the text.

Hereditary Non-Polyposis Colorectal Cancer (HNPCC) is a hereditary malignant syndrome which leaves the individual highly susceptible to other forms of cancer.
HNPCC is also known as Syndrome

Explanation

Question 4 of 22

1

Lynch Syndrome, as well as predisposing the individual to colorectal cancer (HNPCC), also leaves the individual at high risk of which three of the following cancers?

Select one or more of the following:

Endometrial cancer
Breast cancer
Ovarian cancer
Vulval cancer
Lung cancer
Oesophageal cancer

Explanation

Question 5 of 22

1

Which two of the following are Type I Endometrial Carcinomas?

Select one or more of the following:

Endometrioid
Serous
Clear Cell
Mucinous

Explanation

Question 6 of 22

1

Which two of the following are Type II Endometrial Carcinomas?

Select one or more of the following:

Endometrioid
Mucinous
Serous
Clear Cell

Explanation

Question 7 of 22

1

❌ Endometrial Carcinomas are associated with unopposed Oestrogen and atypical hyperplasia
❌ Endometrial Carcinomas are associated with TP53 mutation

Drag and drop to complete the text.

Type II

Type I

Explanation

Question 8 of 22

1

A serous endometrial carcinoma is associated with unopposed oestrogen

Select one of the following:

True
False

Explanation

Question 9 of 22

1

Atypical hyperplasia is a precursor to clear cell endometrial carcinoma

Select one of the following:

True
False

Explanation

Question 10 of 22

1

The precursor to endometrioid carcinoma is atypical hyperplasia.

Select one of the following:

True
False

Explanation

Question 11 of 22

1

Mucinous Endometrial Carcinomas are associated with TP53 mutation

Select one of the following:

True
False

Explanation

Question 12 of 22

1

Mucinous Endometrial Carcinomas are associated with unopposed oestrogen.

Select one of the following:

True
False

Explanation

Question 13 of 22

1

Which of the following are associated with Microsatellite Instability?

Select one or more of the following:

Endometrioid Endometrial Carcinoma
Mucinous Endometrial Carcinoma
Serous Endometrial Carcinoma
Clear Cell Endometrial Carcinoma

Explanation

Question 14 of 22

1

Fill the blank space to complete the text.

Which condition is defined as the following?

"Germline mutation of DNA mismatch repair genes"

Explanation

Question 15 of 22

1

Obesity is a highly substantial risk factor for endometrial carcinoma

Select one of the following:

True
False

Explanation

Question 16 of 22

1

Fill the blank space to complete the text.

Obesity is a risk factor for endometrial carcinoma as fat cells called adipocytes express an enzyme called which converts ovarian androgens into oestrogens, thus promoting endometrial proliferation.

Explanation

Question 17 of 22

1

Fill the blank space to complete the text.

Lynch Syndrome has an autosomal inheritance pattern

Explanation

Question 18 of 22

1

One of the characteristic traits of Lynch Syndrome is a lack of Microsatellite Instability

Select one of the following:

True
False

Explanation

Question 19 of 22

1

Type II Endometrial Carcinomas (Serous and Clear Cell) are more aggressive than Type I cancers as they spread along the fallopian tube mucosa allowing extrauterine presentation.

Select one of the following:

True
False

Explanation

Question 20 of 22

1

Which of the following Type II Endometrial Carcinomas is known to spread to the peritoneum early in the disease process?

Select one or more of the following:

Serous Endometrial Carcinoma
Clear Cell Endometrial Carcinoma

Explanation

Question 21 of 22

1

	Created by Matthew Coulson over 5 years ago

Endometrial carcinomas

Uterine Cancer

Question 1 of 22

Select from the dropdown list to complete the text.

Endometrial polyps are a common cause of dysfunctional uterine bleeding and typically occur in post-menopausal pre-pubertal pre-menopausal( post-menopausal, pre-pubertal, pre-menopausal ) women.

Explanation

Question 2 of 22

Select from the dropdown lists to complete the text.

The peak incidence of endometrial carcinoma is 50-60 years 30-40 years 70-80 years( 50-60 years, 30-40 years, 70-80 years ). It is uncommon for endometrial carcinoma to present in those under 40 over 65( under 40, over 65 )

Explanation

Question 3 of 22

Fill the blank space to complete the text.

Hereditary Non-Polyposis Colorectal Cancer (HNPCC) is a hereditary malignant syndrome which leaves the individual highly susceptible to other forms of cancer. HNPCC is also known as Syndrome

Explanation

Question 4 of 22

Lynch Syndrome, as well as predisposing the individual to colorectal cancer (HNPCC), also leaves the individual at high risk of which three of the following cancers?

Select one or more of the following:

Explanation

Question 5 of 22

Which two of the following are Type I Endometrial Carcinomas?

Select one or more of the following:

Explanation

Question 6 of 22

Which two of the following are Type II Endometrial Carcinomas?

Select one or more of the following:

Explanation

Question 7 of 22

❌ Endometrial Carcinomas are associated with unopposed Oestrogen and atypical hyperplasia ❌ Endometrial Carcinomas are associated with TP53 mutation

Drag and drop to complete the text.

Explanation

Question 8 of 22

A serous endometrial carcinoma is associated with unopposed oestrogen

Select one of the following:

Explanation

Question 9 of 22

Atypical hyperplasia is a precursor to clear cell endometrial carcinoma

Select one of the following:

Explanation

Question 10 of 22

The precursor to endometrioid carcinoma is atypical hyperplasia.

Select one of the following:

Explanation

Question 11 of 22

Mucinous Endometrial Carcinomas are associated with TP53 mutation

Select one of the following:

Explanation

Question 12 of 22

Mucinous Endometrial Carcinomas are associated with unopposed oestrogen.

Select one of the following:

Explanation

Question 13 of 22

Which of the following are associated with Microsatellite Instability?

Select one or more of the following:

Explanation

Question 14 of 22

Fill the blank space to complete the text.

Which condition is defined as the following? "Germline mutation of DNA mismatch repair genes"

Explanation

Question 15 of 22

Obesity is a highly substantial risk factor for endometrial carcinoma

Select one of the following:

Explanation

Question 16 of 22

Fill the blank space to complete the text.

Obesity is a risk factor for endometrial carcinoma as fat cells called adipocytes express an enzyme called which converts ovarian androgens into oestrogens, thus promoting endometrial proliferation.

Explanation

Question 17 of 22

Fill the blank space to complete the text.

Lynch Syndrome has an autosomal inheritance pattern

Explanation

Question 18 of 22

One of the characteristic traits of Lynch Syndrome is a lack of Microsatellite Instability

Select one of the following:

Explanation

Question 19 of 22

Type II Endometrial Carcinomas (Serous and Clear Cell) are more aggressive than Type I cancers as they spread along the fallopian tube mucosa allowing extrauterine presentation.

Select one of the following:

Explanation

Question 20 of 22

Which of the following Type II Endometrial Carcinomas is known to spread to the peritoneum early in the disease process?

Endometrial polyps are a common cause of dysfunctional uterine bleeding and typically occur in ( post-menopausal, pre-pubertal, pre-menopausal ) women.

The peak incidence of endometrial carcinoma is ( 50-60 years, 30-40 years, 70-80 years ).
It is uncommon for endometrial carcinoma to present in those ( under 40, over 65 )

Hereditary Non-Polyposis Colorectal Cancer (HNPCC) is a hereditary malignant syndrome which leaves the individual highly susceptible to other forms of cancer.
HNPCC is also known as Syndrome

❌ Endometrial Carcinomas are associated with unopposed Oestrogen and atypical hyperplasia
❌ Endometrial Carcinomas are associated with TP53 mutation

Which condition is defined as the following?

"Germline mutation of DNA mismatch repair genes"