Mer Scott
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PHCY310 Quiz on L13 Asthma, created by Mer Scott on 09/04/2019.

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Mer Scott
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L13 Asthma

Question 1 of 10

1

Asthma is an dysfunction, an response to a non-pathogenic antigen, therefore an atopic or allergic immune response.
• Type hypersensitivity
• Antibody –
– T cells, B cells, mast cells, eosinophils
• 2 phases – & inflammation

Drag and drop to complete the text.

    immune
    inflammatory
    I & IV
    IgE
    Cells
    sensitisation

Explanation

Question 2 of 10

1

The is the relationship between ashtma, atopic dermatitis(AD) and allergic rhinitis(AR) in children. Children with one condition often will also have .
Food also occurs frequently in children with AD or AD.

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    Atopic March
    another
    atopic
    allergy
    precedes

Explanation

Question 3 of 10

1

The first stage of asthma pathology is the . A cell in the lungs encounters an allergen and becomes activated, then travels to a node. T cell activation and occurs, which releases , and activates B cells. B cells proliferate and release antibodies.
The second stage is inflammation. IgE coated/sensitised cells and eosinophils in the lungs encounter the allergen and , releasing histamines, proteases, leukotrienes, and prostaglandins which inflame the airways.

Drag and drop to complete the text.

    sensitisation
    dendritic
    lymph
    proliferation
    interleukins
    IgE
    mast
    degranulate

Explanation

Question 4 of 10

1

Choose the correct statement.

Select one of the following:

  • Th2 cells produce cytokines that drive IgE production by B cells

  • Eosinophils release bronchoconstrictors & cytokines

  • Mast cells release mediators that damage cells, and contribute to remodeling

Explanation

Question 5 of 10

1

Non-atopic asthma, also known as asthma, is asthma atopy. A skin test will be . Commonly in women, and usually in adults.
There are some differences (debated); the presence of lymphoid cells (ILCs), and IgE, for example.
Neutrophilic asthma is another type. It is usually onset and severe, and less reversible. There are some differences; rather than Th2, rather than eosinophils. It is corticosteroid .
Occupational asthma is another type.

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    intrinsic
    without
    negative
    innate
    less
    late
    more
    Th17
    neutrophils
    insensitive

Explanation

Question 6 of 10

1

The pathophysiology of asthma includes inflammation, hyperresponsiveness/bronchoconstriction, oedema, and remodelling. Inflammation is quite complex and impacts decision. Hyperresponsiveness is early on and can be measured. Oedema is due to hypersecretion. Airway remodelling is associated with a progressive, loss of lung function. It includes the thickening of the membrane, fibrosis, airway smooth muscle and hyperplasia, angiogenesis, and mucus gland hyperplasia.

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    treatment
    reversible
    mucus
    irreversible
    basement
    hypertrophy

Explanation

Question 7 of 10

1

There is a small but significant dose related association with antibiotics in pediatrics and the development of asthma.

Select one of the following:

  • True
  • False

Explanation

Question 8 of 10

1

There is a dose dependent association between paracetamol use in first
year of life and asthma, i.e. paracetamol increases the risk of asthma.

Select one of the following:

  • True
  • False

Explanation

Question 9 of 10

1

NZ's rate of asthma in the population is:

Select one of the following:

  • low and stable

  • low and fluctuating

  • high and stable

  • high and fluctuating

Explanation

Question 10 of 10

1

In conventional asthma treatment and management, we:
- Abolish symptoms - (relievers)
- Restore best possible airway function - anti-inflammatory drugs ()
- Practice allergen

Drag and drop to complete the text.

    Beta agonists
    preventers
    avoidance

Explanation