Matthew Coulson
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Honours Degree Medicine (Transition Block) Quiz on Transition Block - Biochemistry, created by Matthew Coulson on 13/04/2019.

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Matthew Coulson
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Transition Block - Biochemistry

Question 1 of 14

1

Fill the blank space to complete the text.

Which ADP analogue is used to differentiate between central and nephrogenic diabetes insipidus?

Explanation

Question 2 of 14

1

Non-osmotic stimuli and osmotic stimuli (hypernatraemia) cause similar increases in ADH

Select one of the following:

  • True
  • False

Explanation

Question 3 of 14

1

Select from the dropdown list to complete the text.

In patients with suppression of the HPA axis by long-term prescription of prednisolone, ( 7.5 mg, 5.0 mg, 2.5 mg, 1.0 mg ) daily reliably provides adequate steroid replacement, i.e. the patient is getting enough exogenous steroid to cover any insufficiency of endogenous steroid production.

Explanation

Question 4 of 14

1

Patients with adrenal insufficiency are less able to retain infused saline (sodium) than normal subjects due to low levels of Aldosterone meaning they simply just pass the infused Sodium in the urine.

Select one of the following:

  • True
  • False

Explanation

Question 5 of 14

1

Select from the dropdown list to complete the text.

Cortisol levels are typically at their daily peak in the ( morning, evening )

Explanation

Question 6 of 14

1

A significant increase in which of the following hormones would cause an individual to appear sufficiently more tanned?

Select one of the following:

  • ACTH

  • GnRH

  • FSH

  • LH

  • Prolactin

  • TSH

Explanation

Question 7 of 14

1

indicates a secondary adrenal insufficiency (problem with pituitary)
indicates a primary adrenal insufficiency (problem with adrenal gland)

Drag and drop to complete the text.

    High ACTH levels
    Low ACTH levels

Explanation

Question 8 of 14

1

Select from the dropdown list to complete the text.

Addison's Disease typically results in ( increased, decreased ) levels of ACTH

Explanation

Question 9 of 14

1

Which 2 of the following are specific cations that are exchanged for sodium as part of the mineralocorticoid activity?

Select one or more of the following:

  • K+

  • H+

  • Ca+

  • Cl-

  • Zn+

Explanation

Question 10 of 14

1

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After being taken in rural GP settings, blood samples are sometimes kept in a fridge overnight due to long transit times between themselves and the hospital. During this time, there is leakage of ( potassium, calcium, sodium, chloride ) from the ICF into the ECF. Therefore, when the sample is eventually analysed in the hospital they find a raised level of this mineral. This is called ( Pseudohyperkalaemia, Pseudohypernatraemia, Pseudohypercalcaemia, Pseudohyperchloride )

Explanation

Question 11 of 14

1

After haemolysis and renal failure, which two of the following are the most common causes of Hyperkalaemia in patients?

Select one or more of the following:

  • ACE Inhibitors

  • Spironolactone

  • Thiazide Diuretics

  • Beta Blockers

  • Calcium Channel Blockers

Explanation

Question 12 of 14

1

Fill the blank space to complete the text.

On ECG, tented T waves and a shortened QT interval is indicative of

Explanation

Question 13 of 14

1

Potassium treatment should always be given in DKA even if Potassium levels are normal

Select one of the following:

  • True
  • False

Explanation

Question 14 of 14

1

What is the key mechanism by which the kidneys regulate blood volume?

Select one of the following:

  • Excretion of Sodium

  • Excretion of Calcium

  • Excretion of Potassium

  • Excretion of Zinc

  • Excretion of Iron

Explanation

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