Matthew Coulson
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Honours Degree Medicine (Transition Block) Quiz on Transition Block - Pharmacology, created by Matthew Coulson on 13/04/2019.

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Matthew Coulson
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Transition Block - Pharmacology

Question 1 of 17

1

Which of the following drugs is not used as secondary prevention for myocardial infarction?

Select one of the following:

  • Aspirin

  • Furosemide

  • Simvastatin

  • Ramipril

  • Bisoprolol

Explanation

Question 2 of 17

1

Which of the following drugs is most likely to cause hyperkalaemia?

Select one of the following:

  • Allopurinol

  • Furosemide

  • Simvastatin

  • Ramipril

  • Metformin

Explanation

Question 3 of 17

1

Fill the blank spaces to complete the text.

For Acute treatment of an MI, consider MONA + T:
M =
O =
N =
A =
T =

Explanation

Question 4 of 17

1

Omeprazole should be used with caution in patients with renal failure

Select one of the following:

  • True
  • False

Explanation

Question 5 of 17

1

Select from the dropdown list to complete the text.

Km is the concentration at which a drug works at ( 25%, 50%, 75%, 90% ) of its Vmax

Explanation

Question 6 of 17

1

Which of the following drugs will not interact pharmacodynamically with the others listed to cause hypotension?

Select one of the following:

  • Simvastatin

  • Furosemide

  • Bisoprolol

  • Ramipril

  • Isosorbide Mononitrate

Explanation

Question 7 of 17

1

For a drug that exhibits 1st order kinetics administered by IV infusion, a steady state plasma concentration is achieved when the rate of administration equals the half of the rate of elimination

Select one of the following:

  • True
  • False

Explanation

Question 8 of 17

1

A patient recently started on a new medication has been experiencing constant pains in her muscles. She is an avid grapefruit juice fan. What medication is she taking?

Select one of the following:

  • Simvastatin

  • Bisoprolol

  • Ramipril

  • Furosemide

  • Isosorbide Mononitrate

Explanation

Question 9 of 17

1

Select from the dropdown list to complete the text.

Furosemide is mainly excreted via the ( kidneys, liver )

Explanation

Question 10 of 17

1

Before surgery, for how many days should warfarin therapy be stopped?

Select one of the following:

  • 14

  • 10

  • 7

  • 5

Explanation

Question 11 of 17

1

Treatment of paracetamol overdose:

Select one of the following:

  • n-acetylcysteine

  • n-acetylglucosamine

  • n-acetylmuramic acid

  • n-acetylcysteamine

  • n-acetylcarnosine

Explanation

Question 12 of 17

1

Both Viagra and isosorbide mononitrate are vasodilators so given in conjunction this would cause syncope

Select one of the following:

  • True
  • False

Explanation

Question 13 of 17

1

Which of the following pain relief options is suitable for a patient taking Warfarin?

Select one of the following:

  • Paracetamol

  • Aspirin

  • Naproxen

  • Diclofenac

  • Ibuprofen

Explanation

Question 14 of 17

1

Select from the dropdown list to complete the text.

The in vivo effects of paracetamol are similar to those of the ( selective cyclooxygenase-2 (COX-2), selective cyclooxygenase-1 (COX-1) ) inhibitors.

Explanation

Question 15 of 17

1

Select from the dropdown list to complete the text.

In a drug which shows first order elimination kinetics, how many half lives does it take for the drug to be fully excreted from the body?
( 5, 2, 3, 4 ) half lives

Explanation

Question 16 of 17

1

Select from the dropdown list to complete the text.

Cyclizine is a histamine ( type 1, type 2 ) antagonist used as an antiemetic (first line in pregnancy morning sickness)

Explanation

Question 17 of 17

1

Select from the dropdown list to complete the text.

Allopurinol should not be given in a dose higher than ( 100, 1, 10 )mg per day

Explanation

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