L31 Type 2 DM

Question 1 of 7

1

Select from the dropdown lists to complete the text.

Diabetes Mellitus is a metabolic disorder resulting from high concentrations of blood glucose.
Glucose remains in the
blood, therefore:
• ( Increased, Decreased ) urination
• Thirsty
• Weight ( loss, gain )
• Tired
• ( Poor, Good ) circulation

Explanation

Question 2 of 7

1

T2DM is due to insulin deficiency (Beta islet cell dysfunction & cell loss up to 50% at diagnosis), and insulin resistance.

Select one of the following:

True
False

Explanation

Question 3 of 7

1

Metabolic syndrome is associated with excess nutrition, insufficient ❌ and a genetic predisposition. It is characterised by chronic ❌ in the adipose tissue, liver, pancreas, and vasculature.
• Doubles the risk of ❌ heart disease
• Doubles risk of stroke
• Five times the risk of ❌
• Increased risk of venous thrombosis

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exercise

inflammation

diabetes

atherosclerotic

Explanation

Question 4 of 7

1

HbA1c is glycosylated haemoglobin. It can be used to determine plasma ❌ over the previous 8-12 ❌ and so ❌ diabetic control or ❌ diabetes. The more glucose in the blood, the more haemoglobin is ❌.

Drag and drop to complete the text.

glucose

weeks

monitor

diagnose

glycosylated

Explanation

Question 5 of 7

1

The lifetime risk of a child with 1 parent with T2D is 40%, and increases to 70% if both parents have/had T2D.

Select one of the following:

True
False

Explanation

Question 6 of 7

1

Type 2 Diabetes - Pathogenesis:
• Insulin resistance begins many ❌ before onset of T2D
• When insulin ❌ can not overcome ❌: hyperglycaemia and T2D
• Typically ❌ of B islet cells left at diagnosis
• Abnormalities in other hormones (increased ❌) & impaired responses to others (egg GLP-1)
• Changes in gut ❌
• Inflammation

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years

secretion

resistance

half

glucagon

microbiota

Explanation

Question 7 of 7

1

Pathophysiology of T2DM:
- Macrovascular (50% of patients): ❌, develops earlier and is more severe
- Microvascular (~27% patients): ❌
- Co-morbidities: non-alcoholic ❌ disease, obstructive sleep ❌ and depression

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cardiovascular disease

kidney, retina and the nervous system

fatty liver

apnoea

	Created by Mer Scott over 5 years ago

PHCY310 Quiz on L31 Type 2 DM, created by Mer Scott on 16/04/2019.

L31 Type 2 DM

Question 1 of 7

Select from the dropdown lists to complete the text.

Diabetes Mellitus is a metabolic disorder resulting from high concentrations of blood glucose. Glucose remains in the blood, therefore: • Increased Decreased( Increased, Decreased ) urination • Thirsty • Weight loss gain( loss, gain ) • Tired • Poor Good( Poor, Good ) circulation

Explanation

Question 2 of 7

T2DM is due to insulin deficiency (Beta islet cell dysfunction & cell loss up to 50% at diagnosis), and insulin resistance.

Select one of the following:

Explanation

Question 3 of 7

Drag and drop to complete the text.

Explanation

Question 4 of 7

HbA1c is glycosylated haemoglobin. It can be used to determine plasma ❌ over the previous 8-12 ❌ and so ❌ diabetic control or ❌ diabetes. The more glucose in the blood, the more haemoglobin is ❌.

Drag and drop to complete the text.

Explanation

Question 5 of 7

The lifetime risk of a child with 1 parent with T2D is 40%, and increases to 70% if both parents have/had T2D.

Select one of the following:

Explanation

Question 6 of 7

Drag and drop to complete the text.

Explanation

Question 7 of 7

Pathophysiology of T2DM: - Macrovascular (50% of patients): ❌, develops earlier and is more severe - Microvascular (~27% patients): ❌ - Co-morbidities: non-alcoholic ❌ disease, obstructive sleep ❌ and depression

Drag and drop to complete the text.

Explanation

Diabetes Mellitus is a metabolic disorder resulting from high concentrations of blood glucose.
Glucose remains in the
blood, therefore:
• ( Increased, Decreased ) urination
• Thirsty
• Weight ( loss, gain )
• Tired
• ( Poor, Good ) circulation

Pathophysiology of T2DM:
- Macrovascular (50% of patients): ❌, develops earlier and is more severe
- Microvascular (~27% patients): ❌
- Co-morbidities: non-alcoholic ❌ disease, obstructive sleep ❌ and depression