Biochemistry Year 1

Question 1 of 40

1

Which set-up forms the strongest hydrogen bonds?

Select one of the following:

When atoms are at a 90 degree angle from the hydrogen atom.
When the atoms are all in a straight line.
When atoms are at less than 60 degrees from the hydrogen atom.
When atoms are more than 60 degrees from the hydrogen atom.

Explanation

Question 2 of 40

1

At which distance are van der Waals interactions the strongest?

Select one of the following:

At the van der Waals contact distance.
At less than the van der Waals contact distance.
At more than the van der Waals contact distance.
When the nuclei of the two atoms are 0.5 angstrom away from each other.

Explanation

Question 3 of 40

1

Why does the formation of the DNA double helix release heat?

Select one of the following:

It doesn't release heat, it absorbs it.
Because the formation of the double helix is a decrease in entropy, thus heat must be released to increase it and make the reaction favourable.
The overall net formation of hydrogen bonds releases energy as heat.
Because the enzymes that do it couple the reaction with another one that releases heat.

Explanation

Question 4 of 40

1

What does pKa represent?

Select one of the following:

The susceptibility of a proton to be removed by a reaction with a base.
The susceptibility of a proton to be removed by a reaction with an acid.
The pH at which the concentration of protons is equal to the concentration of OH- for a substance.
The pH at which the concentration of the protonated form of a substance is equal to the concentration of OH-.

Explanation

Question 5 of 40

1

What is the Pauli exclusion principle?

Select one of the following:

Only two electrons may be placed in each orbital, and these must have opposite spins.
Only two electrons may be placed in each orbital.
If two or more orbitals of equal energy are available, then one electron must be placed in each orbital until they are half full.
The combining of atomic orbitals within an atom to form new orbitals.

Explanation

Question 6 of 40

1

Which is not a polar amino acid?

Select one of the following:

Leucine
Methionine
Tryptophan
Serine

Explanation

Question 7 of 40

1

Which is not a force that notably stabilises protein structure?

Select one of the following:

Hydrogen bonds
Ionic interactions
van der Waals interactions
Steric clashes

Explanation

Question 8 of 40

1

What is the dielectric constant of a solvent?

Select one of the following:

A measure of the solvent's ability to keep opposite charges apart.
A measure of the solvent's ability to keep opposite charges together.
A measure of the solvent's ability to keep like charges together.
A measure of the solvent's ability to keep like charges apart.

Explanation

Question 9 of 40

1

What did the Anfinsen experiment determine?

Select one of the following:

The sequence of amino acids is sufficient and necessary for protein folding.
Which codon represents which amino acid.
DNA is the molecule which stores genetic information.
Correct protein folding sometimes requires chaperone proteins.

Explanation

Question 10 of 40

1

Which is the macro positive end in a amino acid alpha helix?

Select one of the following:

N terminus
C terminus
Tryptophan end
The end which is central to the protein

Explanation

Question 11 of 40

1

What is the difference between the equilibrium constant and the mass action ratio?

Select one of the following:

The mass action ratio depends on actual concentrations, while the equilibrium constant depends on the concentrations at equilibrium.
The mass action ratio depends on theoretical concentrations, while the equilibrium constant depends on the concentrations at equilibrium.
The mass action ratio depends on concentrations at equilibrium, while the equilibrium constant depends on the actual concentrations.
The mass action ratio depends on theoretical concentrations, while the equilibrium constant depends on the actual concentrations.

Explanation

Question 12 of 40

1

What is the standard state?

Select one of the following:

The concentrations of all reactants and products at equilibrium.
When all reactants have a concentration of 1M.
When all products and reactants have a concentration of 1M.
When there are equal concentrations of products and reactants at any concentration.

Explanation

Question 13 of 40

1

Which is a microfilament?

Select one of the following:

Actin
Tubulin
Actin and tubulin
Myosin

Explanation

Question 14 of 40

1

Which is the monomeric form of actin?

Select one of the following:

G-actin
F-actin
M-actin
T-actin

Explanation

Question 15 of 40

1

Why are the initial stages of actin polymerisation slow?

Select one of the following:

It is energetically unfavourable.
It's energetically favourable
The associated Mg2+ cations slow the process down
There is never enough actin monomers accumulated in one area

Explanation

Question 16 of 40

1

What anchors actin to the cell membrane?

Select one of the following:

Dystrophin
CAPZ
Fimbrin
Tubulin

Explanation

Question 17 of 40

1

What is the function of filamin?

Select one of the following:

Creating networks of F-actin as a gelation protein.
Severing actin filaments which leads to dissociation of the filament.
Prevents the formation of actin clots.
Generation of higher order structures.

Explanation

Question 18 of 40

1

Which myosin is found in sarcomeres?

Select one of the following:

Myosin II
Myosin I
Myosin IV
Myosin V

Explanation

Question 19 of 40

1

Which is NOT an example of the function of stable microtubules?

Select one of the following:

Reorganisation of chromosomes during division
Intracellular transport
Form an integral part of the neuronal axon
Form the backbone of cilia

Explanation

Question 20 of 40

1

Which tubulin subunit(s) binds GTP irreversibly?

Select one of the following:

Alpha subunit
Beta subunit
Both alpha and beta subunits
Neither alpha nor beta subunits

Explanation

Question 21 of 40

1

Why is axonal transport the model system for microtubules?

Select one of the following:

It is stable.
The beta tubulin ringed side has a faster rate of growth than the alpha tubulin side.
The dissociation of GDP-tubulin once the cap is lost is slower than in other systems.
It only has kinesin motors, making it simple to observe.

Explanation

Question 22 of 40

1

Which is true?

Select one of the following:

Actin can be highly branched, while microtubules cannot.
Microtubules can be highly branched, while actin cannot.
Myosin can be highly branched, while actin cannot.
Myosin can be highly branched, while microtubules cannot.

Explanation

Question 23 of 40

1

Which is NOT a basic type of reaction?

Select one of the following:

Group transfer
Addition/removal of functional groups
Hydrolysis
Fermentation

Explanation

Question 24 of 40

1

Which is a benefit of compartmentalisation?

Select one of the following:

Substrate channeling
Formation of proteinaceous compartments
Futile cycling
Metabolic flux

Explanation

Question 25 of 40

1

Which is the group carried in a high energy linkage in NADH?

Select one of the following:

Hydrogen
Electrons and hydrogen
Carboxyl group
Methyl group

Explanation

Question 26 of 40

1

Why does ATP have the potential to do work as an energy store?

Select one of the following:

The reaction ATP<=>ADP+Pi is maintained favouring the formation of ATP
The reaction ATP<=>ADP+Pi is displaced from the equilibrium ratio
The reaction ATP<=>ADP+Pi favours ADP+Pi
The The reaction ATP<=>ADP+Pi is maintained within the cell favouring ADP+Pi

Explanation

Question 27 of 40

1

Which is NOT a method of studying metabolic pathways?

Select one of the following:

Inhibitors
Cell fragmentation
Radiolabelling
Mutants

Explanation

Question 28 of 40

1

Which enzyme catalyses the conversion of glucose to glucose-6-phosphate?

Select one of the following:

Hexokinase
Aldolase
Glyceraldehyde-3-phosphate dehydrogenase
Enolase

Explanation

Question 29 of 40

1

At which point of glycolysis is there allosteric inhibition to control the entry of sugars into glycolysis?

Select one of the following:

Phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate by phosphofructokinase
Cleavage of fructose-1,6-bisphosphate to dihydroxyacetone phosphate and glyceraldehyde phosphate by aldolase
Oxidation of glyceraldehyde-3-phosphate using glyceraldehyde-3-phosphate dehydrogenase
Conversion of glucose to glucose-6-phosphate by hexokinase

Explanation

Question 30 of 40

1

Which is an example of a kinetically perfect enzyme in glycolysis?

Select one of the following:

Triose phosphate isomerase
Hexokinase
Phosphofructokinase
Aldolase

Explanation

Question 31 of 40

1

Where are the enzymes pyruvate decarboxylase, dihydrolipoyl transacetylase, and dihydrolipoyl dehydrogenase located in the cell?

Select one of the following:

Mitochondrial matrix
Mitochondrial intermembrane space
Cytoplasm
Cell membrane

Explanation

Question 32 of 40

1

Coenzyme A is an activated carrier molecule. By what kind of a linkage does it carry its acetyl group?

Select one of the following:

Thioester linkage
Ester linkage
Esther linkage
Phosphodiester linkage

Explanation

Question 33 of 40

1

Malonate closely resembled which molecule?

Select one of the following:

Succinate
Fumarate
Malate
Citrate

Explanation

Question 34 of 40

1

What is the function of aconitase?

Select one of the following:

Citrate isomerisation
Phosphate group transfer from 1,3-bisphosphoglycerate to ADP
Removal of water from 2-phosphoglycerate
Decarboxylation of isocitrate

Explanation

Question 35 of 40

1

Which complex serves as succinate dehydrogenase?

Select one of the following:

Complex I
Complex II
Complex III
Complex IV

Explanation

Question 36 of 40

1

How many protons are required to form a single ATP molecule?

Select one of the following:

4
2.5
1.5
6

Explanation

Question 37 of 40

1

Which complex does not directly pump any protons into the intermembrane space in mitochondria?

Select one of the following:

Complex I
Complex II
Complex III
Complex IV

Explanation

Question 38 of 40

1

What does respiratory control refer to?

Select one of the following:

The inhibition of complex II by malonate
Proton 'back pressure' restricting electron flow
The breaking down of ATP to ADP+Pi by the cell to keep the ATP concentration low
The inhibition of the electron transport chain by the lack of oxygen

	Created by Nicole Rogowski over 5 years ago

All of Biochemistry subject knowledge from textbook and lectures.

Biochemistry Year 1

Question 1 of 40

Which set-up forms the strongest hydrogen bonds?

Select one of the following:

Explanation

Question 2 of 40

At which distance are van der Waals interactions the strongest?

Select one of the following:

Explanation

Question 3 of 40

Why does the formation of the DNA double helix release heat?

Select one of the following:

Explanation

Question 4 of 40

What does pKa represent?

Select one of the following:

Explanation

Question 5 of 40

What is the Pauli exclusion principle?

Select one of the following:

Explanation

Question 6 of 40

Which is not a polar amino acid?

Select one of the following:

Explanation

Question 7 of 40

Which is not a force that notably stabilises protein structure?

Select one of the following:

Explanation

Question 8 of 40

What is the dielectric constant of a solvent?

Select one of the following:

Explanation

Question 9 of 40

What did the Anfinsen experiment determine?

Select one of the following:

Explanation

Question 10 of 40

Which is the macro positive end in a amino acid alpha helix?

Select one of the following:

Explanation

Question 11 of 40

What is the difference between the equilibrium constant and the mass action ratio?

Select one of the following:

Explanation

Question 12 of 40

What is the standard state?

Select one of the following:

Explanation

Question 13 of 40

Which is a microfilament?

Select one of the following:

Explanation

Question 14 of 40

Which is the monomeric form of actin?

Select one of the following:

Explanation

Question 15 of 40

Why are the initial stages of actin polymerisation slow?

Select one of the following:

Explanation

Question 16 of 40

What anchors actin to the cell membrane?

Select one of the following:

Explanation

Question 17 of 40

What is the function of filamin?

Select one of the following:

Explanation

Question 18 of 40

Which myosin is found in sarcomeres?

Select one of the following:

Explanation

Question 19 of 40

Which is NOT an example of the function of stable microtubules?

Select one of the following:

Explanation

Question 20 of 40

Which tubulin subunit(s) binds GTP irreversibly?