ON3 Aseptics/Chemo Hazards

Question 1 of 11

1

Select from the dropdown lists to complete the text.

( Sterile, Aseptic ) means free from all microbiological contaminants i.e. living organisms, particles, and pyrogens.
( Aseptic, Sterile ) means produced from sterile components in a sterile environment – however it does NOT guarantee sterility.
Pharmacists generally work in ( aseptic, sterile ) conditions with ( sterile, aseptic ) starting materials to prepare aseptic products.

Explanation

Question 2 of 11

1

Contamination/L
• Viable (❌): Bacteria, fungi, and viruses.
Administration of viable material could result in fever; infection; septicemia; multi-organ failure; death.
• Non-viable: ❌ particulate matter e.g. plastic or rubber material, glass shards, and chemical precipitates.
Non-viable material may ❌ vessels e.g. if >12 μm they may become trapped in the lungs leading to respiratory failure and death.

Drag and drop to complete the text.

live

Undissolved

occlude

Explanation

Question 3 of 11

1

What is laminar flow air?

Select one of the following:

Smooth, steady, constant flow.
Turbulent, rapid flow.

Explanation

Question 4 of 11

1

Clean air eg a ❌-free working environment, is made by drawing laminar air into the ❌, through the ❌ system.
• HEPA-filtered air (❌ filter)
• High airflow, ❌ filtered and replenished

Drag and drop to complete the text.

particle

cabinet

filtration

high-efficiency particulate air

constantly

Explanation

Question 5 of 11

1

In horizontal air flow the product is protected but the operator is not. Vertical air flow protects both the product and operator.

Select one of the following:

True
False

Explanation

Question 6 of 11

1

Choose the incorrect statement.

Select one of the following:

Critical points on equipment should never be exposed to clean air
Starting materials are removed from their outer wrapping before entering the clean room – minimises the generation of particulate matter in the clean room.
Needles are mostly used for one manipulation only, either withdrawing from a container or transferring into a container.
After spraying with 70% ethanol, allow time for the ethanol to evaporate.

Explanation

Question 7 of 11

1

Critical Points on a Syringe:
Any ‘connection’ point:
• Tip of ❌
• Hub of needle & tip of filter
• Hub of filter & tip of syringe
• Syringe ❌

Drag and drop to complete the text.

needle

plunger

Explanation

Question 8 of 11

1

Pharmacist involvement:
• ❌ of cytotoxics
– Preserve safety of self and product
• ❌ of cytotoxics
– Calculations
– Precise and accurate ❌ must be given
• Advising nursing staff how to administer cytotoxic products
• Providing medicines information and advice

Drag and drop to complete the text.

Preparation

Dispensing

instructions

Explanation

Question 9 of 11

1

Administration of any IV medicine carries a risk of extravasation (❌ from vein into tissue). This is NOT a side effect. Regarding extravasation:
• Common term is “tissued”
• Can result in pain, swelling, and ❌ at the injection site
• If the drug is a ❌ (causes blistering) it can cause severe tissue damage and necrosis (and can continue for months after injury)
• Oncology nurses take ❌ care to ensure extravasation does not occur
• Patients must be educated to report any discomfort and/or pain ❌ administration

Drag and drop to complete the text.

leakage

damage

vesicant

extreme

during

Explanation

Question 10 of 11

1

Central lines (catheters for administration)
• Via jugular or subclavian ❌ with tip at superior vena cava (e.g. Hickman port, double/single lumen).
• PICC (peripherally-inserted central catheter), starts at the ❌ and is placed centrally

Drag and drop to complete the text.

vein

arm

Explanation

Question 11 of 11

1

Cytotoxic drugs are potentially lethal especially if delivered via the ❌ route.
• Dose varies ❌ between intramuscular (IM), intravenous (IV), and intrathecal (IT – the space that holds the ❌) routes
• The formulation may vary between routes
eg ❌ is often given intrathecally, but ❌ is fatal by this route

Drag and drop to complete the text.

wrong

greatly

CSF

vincristine

Methotrexate

	Created by Mer Scott almost 5 years ago

PHCY320 (Oncology) Quiz on ON3 Aseptics/Chemo Hazards, created by Mer Scott on 05/10/2019.

ON3 Aseptics/Chemo Hazards

Question 1 of 11

Select from the dropdown lists to complete the text.

Explanation

Question 2 of 11

Drag and drop to complete the text.

Explanation

Question 3 of 11

What is laminar flow air?

Select one of the following:

Explanation

Question 4 of 11

Clean air eg a ❌-free working environment, is made by drawing laminar air into the ❌, through the ❌ system. • HEPA-filtered air (❌ filter) • High airflow, ❌ filtered and replenished

Drag and drop to complete the text.

Explanation

Question 5 of 11

In horizontal air flow the product is protected but the operator is not. Vertical air flow protects both the product and operator.

Select one of the following:

Explanation

Question 6 of 11

Choose the incorrect statement.

Select one of the following:

Explanation

Question 7 of 11

Critical Points on a Syringe: Any ‘connection’ point: • Tip of ❌ • Hub of needle & tip of filter • Hub of filter & tip of syringe • Syringe ❌

Drag and drop to complete the text.

Explanation

Question 8 of 11

Pharmacist involvement: • ❌ of cytotoxics – Preserve safety of self and product • ❌ of cytotoxics – Calculations – Precise and accurate ❌ must be given • Advising nursing staff how to administer cytotoxic products • Providing medicines information and advice

Drag and drop to complete the text.

Explanation

Question 9 of 11

Drag and drop to complete the text.

Explanation

Question 10 of 11

Central lines (catheters for administration) • Via jugular or subclavian ❌ with tip at superior vena cava (e.g. Hickman port, double/single lumen). • PICC (peripherally-inserted central catheter), starts at the ❌ and is placed centrally

Drag and drop to complete the text.

Explanation

Question 11 of 11

Drag and drop to complete the text.

Explanation

Clean air eg a ❌-free working environment, is made by drawing laminar air into the ❌, through the ❌ system.
• HEPA-filtered air (❌ filter)
• High airflow, ❌ filtered and replenished

Critical Points on a Syringe:
Any ‘connection’ point:
• Tip of ❌
• Hub of needle & tip of filter
• Hub of filter & tip of syringe
• Syringe ❌

Pharmacist involvement:
• ❌ of cytotoxics
– Preserve safety of self and product
• ❌ of cytotoxics
– Calculations
– Precise and accurate ❌ must be given
• Advising nursing staff how to administer cytotoxic products
• Providing medicines information and advice

Central lines (catheters for administration)
• Via jugular or subclavian ❌ with tip at superior vena cava (e.g. Hickman port, double/single lumen).
• PICC (peripherally-inserted central catheter), starts at the ❌ and is placed centrally